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Xuezhikang Capsuke in CV DIseases

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Hi All, & Jimmy,

 

Re:

>>Zhonghua Nei Ke Za Zhi. 2006 Jan;45(1):21-4. [China coronary

secondary prevention study: analysis of patients with different myocardial

infarction history] [Article in Chinese] Du BM, Lu ZL, Chen Z, Wu YF, Zhao

WD, Huang TG; Collaborative Group of China Coronary Secondary

Prevention Study. Cardiovascular Institute and Fuwai Hospital, Chinese

Academy of Medical Scinence, Peking Union Medical College, Beijing

100037, China. OBJECTIVE: To assess whether Xuezhikang was effective

in the secondary prevention of coronary heart disease (CHD) for patients

with different length of myocardial infarction (MI) history. METHODS: 2135

patients with MI history of 28 days to 3 months and 2735 patients with MI

history of 3 months to 60 months were recruited separately to receive

treatment with Xuezhikang capsule or placebo. The primary end-points

were nonfatal myocardial infarction and death from CHD. RESULTS: The

occurrence of coronary events were found to be not statistically significantly

different for the two groups of patients. For patients with MI history of 28

days to 3 months, Xuezhikang significantly reduced the risk of CHD events

by 56.7% (P < 0.0001) and resulted in a 48.6% (P = 0.0002) risk reduction

in all-cause mortality as compared with placebo. For patients with MI history

of 3 months to 60 months, Xuezhikang significantly decreased the risk of

CHD events by 35.3% (P = 0.0008) and led to a 20.0% (P = 0.1181) risk

reduction in the all-cause mortality as compared with placebo. Adverse

effects and abnormal laboratory parameters did not differ significantly in the

two groups of patients. CONCLUSIONS: Xuezhikang is more effective for

patients with MI history of 28 days to 3 months as compared with patients

with MI history of 3 months to 60 months. Patients with MI history should be

treated with Xuezhikang early in order to achieve better prevention of CHD.

Publication Types: Multicenter Study Randomized Controlled Trial PMID:

16624082 [PubMed - indexed for MEDLINE]

 

See: Red Yeast Rice and Cholesterol - A Critical Review by Dennis Lee MD

at

http://www.medicinenet.com/script/main/art.asp?articlekey=14999 & page=1

and

http://www.medicinenet.com/script/main/art.asp?articlekey=14999 & page=2

 

Best regards,

 

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