Guest guest Posted November 13, 2006 Report Share Posted November 13, 2006 Hi All, & Jimmy, Re: >>Zhonghua Nei Ke Za Zhi. 2006 Jan;45(1):21-4. [China coronary secondary prevention study: analysis of patients with different myocardial infarction history] [Article in Chinese] Du BM, Lu ZL, Chen Z, Wu YF, Zhao WD, Huang TG; Collaborative Group of China Coronary Secondary Prevention Study. Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Scinence, Peking Union Medical College, Beijing 100037, China. OBJECTIVE: To assess whether Xuezhikang was effective in the secondary prevention of coronary heart disease (CHD) for patients with different length of myocardial infarction (MI) history. METHODS: 2135 patients with MI history of 28 days to 3 months and 2735 patients with MI history of 3 months to 60 months were recruited separately to receive treatment with Xuezhikang capsule or placebo. The primary end-points were nonfatal myocardial infarction and death from CHD. RESULTS: The occurrence of coronary events were found to be not statistically significantly different for the two groups of patients. For patients with MI history of 28 days to 3 months, Xuezhikang significantly reduced the risk of CHD events by 56.7% (P < 0.0001) and resulted in a 48.6% (P = 0.0002) risk reduction in all-cause mortality as compared with placebo. For patients with MI history of 3 months to 60 months, Xuezhikang significantly decreased the risk of CHD events by 35.3% (P = 0.0008) and led to a 20.0% (P = 0.1181) risk reduction in the all-cause mortality as compared with placebo. Adverse effects and abnormal laboratory parameters did not differ significantly in the two groups of patients. CONCLUSIONS: Xuezhikang is more effective for patients with MI history of 28 days to 3 months as compared with patients with MI history of 3 months to 60 months. Patients with MI history should be treated with Xuezhikang early in order to achieve better prevention of CHD. Publication Types: Multicenter Study Randomized Controlled Trial PMID: 16624082 [PubMed - indexed for MEDLINE] See: Red Yeast Rice and Cholesterol - A Critical Review by Dennis Lee MD at http://www.medicinenet.com/script/main/art.asp?articlekey=14999 & page=1 and http://www.medicinenet.com/script/main/art.asp?articlekey=14999 & page=2 Best regards, Quote Link to comment Share on other sites More sharing options...
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