Phytoestrogens as substitutes for HRT in osteoporosis & menopausal pathology

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Hi All,

 

I did a medline search today to summarse HM & Phytoestrogens as

substitutes for HRT in osteoporosis & menopausal pathology. For abstracts

of the Medline search, see the FILES AREA of the Discussion List

 

AP, herbal medicine & Tai Ji exercise can help to prevent & treat

osteoporosis & maintain women's health during menopause but well-

designed large studies are still needed.

 

SINGLE HERBS & HERBAL EXTRACTS that may help osteoporosis /

menopausal pathology include:

Berberine;

Buguzi (Boh-Gol-Zhee, Psoralea corylifolia Fr) & extracts & corylin &

bavachin, but massive doses may cause hepatotoxicity;

Bushen Yao (KI-tonifying drugs);

Danshen (Salviae miltiorhizae Rx) tanshinones;

Duzhong (Eucommiae Cx);

Essential oils & monoterpenes;

Gegen (Puerariae lobatae / mirificae Rx); Puerariae Rx had total isoflavone

content circa 30 times more than soybean; other plants from Leguminosae

family, can be a good source of phytoestrogens;

Gouji (Cibotium Barometz Rz, Chain Fern Rz);

Gusuibu (Drynaria fortunei Rz) extract - propelargonidin dimers & trimers

(phytoestrogens);

Heishengma (Cimicifuga racemosa Rz (Black cohosh)) extract (safe for at

least 1 year);

Heiyu (Ulmus davidiana);

Honghuazi / Honghwain;

Huaijiao (Sophora japonica)-extracted genistein (4.5 or 9mg/kg);

Huangqi-Astragali membranacei Rx extract;

Huangshukui (Abelmoschus manihot Rx);

Isoflavones, as from soy;

isoflavonoids richest in Leguminosae family;

Jiegumu (Yuanbianzhong; Sambucus williamsii Rml);

Mianbixie (Dioscorea spongiosa Rz) compounds - spongioside A (5),

hypoglaucin G (7), methylprotodioscin (8), & ®-oct-1-en-3-yl O-alpha-l-

arabinopyranosyl-(1-->6)-alpha-d-glucopyranoside (9);

Nourish / Replenish / Supplement KI & Strengthen Bone Herbs may be

optimal to treat osteoporosis;

Nourish Yin & Purge Fire Hbs;

Nuzhenzi (Ligustri Lucidi Fr);

Osteopractic total flavone;

Pengqiju (Wedelia calendulacea Hb) isoflavones & wedelolactone, known

phytoestrogens;

Phytoestrogens, like soy isoflavones,, DHEA, & vitamin K2 are relatively

safe at normal doses; fashionable but need more evidence of benefit;

Shechuangzi (Cnidii monnieri Fr) & its coumarins;

Suoyang (Cynomorium Hb);

Vegetables, salads & herbs;

Vitamin D supplement useful in old people;

Yanjiaocao (Salicornia herbacea);

Yansheng-Roucongrong (Cistanche salsa);

Yinyanghuo (Epimedii sagittati / brevicorni Hb) extract - Icariin 225mg/kg/d;

other flavonoids; most commonly used CHM for sexual / menopausal

problems;

 

HERBAL FORMULAS that may help osteoporosis / menopausal pathology i

include:

Bawei Wan / Hachimi-jio-gan was as effective as 17beta-estradiol in

preventing bone loss;

Benefit Bone Capsule;

Boron & Boronated compounds (act independently of vitamin D3, enhance

indices of growth cartilage maturation);

Bugu Mixture (Grow Bone Fluid);

Bugu Shengsui Capsule;

Bushen Huoxue Liquid;

Bushen Jiangu Capsule;

Bushen Migu Ye;

Bushen Ningxin Tang;

Bushen Qianggu Capsule;

Bushen Yijing Capsule;

Bushen Zhuanggu Tang;

Chailing Tang / Sairei-to is safe & effective to treat retroperitoneal fibrosis

as an alternative to corticosteroid therapy;

Cheng Zai Wan treats aseptic necrosis of the femoral head;

CWJ [i cannot find any data on its composition];

Dabu? / ?Dabao Yuan Jian / Dae-Bo-Won-Chun;

Danggui Dihuang Yin;

Erxian Tang;

Gengniankang Compound Recipe;

Gubao;

Guchi San;

Gushukang Granule;

Gusongbao;

Gusong-II;

Invigorate KI & Strengthen Bone Capsule;

Jiangu Granule;

Jiawei Guipi Tang / Kami-kihi-to;

Kanggu Song;

Liu'an Qiwei Tang;

Liuwei Dihuang Tang;

Modified Bawei Wan / Hachimi-jio-gan may activate bone metabolism &

prevent / treat bone loss; it has a different target site from vitamin D3;

Modified Bawei Wan / Hachimi-jio-gan was more effective than Bawei Wan

alone for bone loss;

Modified Buzhong Yiqi Tang / Hochu-ekki-to + Bawei Wan / Hachimi-jio-

gan) had no effect in one trial but helped bone structure in other rat trials;

Nourish KI & Strengthen Bone Mixture;

OST-6 (Osteocare);

Qianggu Electuary;

Qianggu Kangwei;

Replenish KI & Activate Blood Circulation Recipe;

Shenxu Gutong Capsule;

Shiquan Dabu Tang / Juzen-taiho-to was as effective as 17beta-estradiol in

preventing bone loss;

Shudi Shanzha (?Rehmannia Prep & Hawthorn) Formula helps menopausal

syndrome;

Supplement Qi, Activate Blood Circulation & Tone KI Formula;

Tone KI & Replenish Qi Formulas improved heart, brain, bone & endocrine

system functions in aged persons;

Tone KI Prescription;

Tone KI Recipe;

Tsu-kan-gan;

Wenbu Shenyang (Warm & Recuperate KI Yang);

Wenjing Tang / Unkei-to can only improve ovary function;

Wenjing Tang / Unkei-to was as effective as 17beta-estradiol in preventing

bone loss;

Xianling Gubao;

Xianzhen Gubao Capsules prevent bone loss induced by corticosteroid;

Yanghuo Sanzi Tang;

Yanhuo Gubao;

Yifuning soft Capsule / Yifuning Soft Gelatin Capsule;

Yigu Capsule;

Zenggu-I, -II, -III sequential therapy could effectively prevent & treat

osteoporosis;

Zhongjiang Tang / Chujo-to;

Zhuanggu Shengbao;

 

Best regards,