Shehuang Paste on navel + Chinese herbal colon dialysis in refractory cirrhotic ascites

[Guest guest]

Hi All,

 

Colleagues, do YOU know (or can you find out) the ingredients and other

professional data

on Shehuang Gao ( she4-huang2-gao1, Shehuang Paste), as used over the navel in

cirrhotic ascites? Phil was unable to find the ingredients on WWW, including

Chinese sites.

 

Tong GD, Zhou DQ, He JS, Zhang L, Chen ZF, Xiao CL, Peng LS. Clinical research

on

navel application of Shehuang Paste combined with Chinese herbal colon dialysis

in

treatment of refractory cirrhotic ascites complicated with azotemia. World J

Gastroenterol.

2006 Dec 28;12(48):7798-804. Department of Hepatology, Shenzhen Hospital of

Traditional

, Guangzhou University of TCM, Shenzhen 518033, Guangdong

Province,

China. tgd755 AIM: To explore the efficacy and mechanism of a novel

therapeutic method of traditional Chinese medicine in patients with refractory

cirrhotic

ascites complicated with azotemia. METHODS: Seventy-five cases of refractory

cirrhotic

ascites complicated with azotemia were randomly divided into 3 groups:

comprehensive

treatment (n = 29), simple treatment (n = 24), and control (n = 22). The basic

treatment

methods were the same in all groups, including liver protecting medicines,

diuretics and

supportive drugs. The control group underwent only the basic treatment. Shehuang

Paste

(SHP) was applied to the navels of the two treatment groups once a day for 30 d.

Colon

dialysis with Chinese herbs was administered to the comprehensive treatment

group once

every two days. Before and after treatment, we measured abdominal circumference,

BUN,

Cr, serum Na(+), urine Na(+)/K(+), liver function, endotoxin content, NO, and

ET-1. Color

Doppler ultrasonography was conducted to measure the portal vein blood flow.

RESULTS:

The total effective rate for ascites was 72.4% in the comprehensive treatment

group, 45.8%

in the simple treatment, contrasting with 18.2% in the controls. Between the two

treatment

groups and the controls, there were significant differences in the effective

rates (P < 0.01,

and P < 0.05). There was also a significant difference (P < 0.05) between the

two treatment

groups. Measurements of Cr and BUN showed higher values for the treatment

groups, with

the comprehensive better than the simple group (P < 0.05). Sera Na, urine Na/K

were

different, P < 0.01 between pre- and post-treatment in the comprehensive group,

and P <

0.05 in the simple group. The treatment groups' endotoxin content was also

significantly

reduced (P < 0.01, and P < 0.05), with the comprehensive group better than the

simple

group (P < 0.05). Portal vein blood flow and NO content significantly reduced (P

< 0.05), as

did ET-1 content (P < 0.01). There were no significant changes in the control

group (P >

0.05). The comprehensive treatment group's pre- and post-treatment portal vein

and splenic

vein blood flows showed a positive correlation to NO, ET-1 and endotoxin

contents.

CONCLUSION: When treating refractory cirrhotic ascites complicated with

azotemia,

Shehuang Paste combined with Chinese herbal dialysis is better than Shehuang

Paste

alone for ascites resolution, azotemia, and endotoxin elimination. However, both

methods

on their own were also effective for reducing portal and splenic vein blood

flow, and lowering

the contents of NO, ET-1 in the two treatment groups. PMID: 17203523 [PubMed -

in

process]

 

See also: http://scholar.ilib.cn/abstract.aspx?A=zgzyykj200305002 and

http://tinyurl.com/ynbj8m or http://tinyurl.com/yhckr7

 

Best regards,

<

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