Serenoa repens as good as Tamsulosin in BPH (benign prostatic hyperplasia)

[Guest guest]

Hi All,

 

Hizli F, Uygur MC. A prospective study of the efficacy of Serenoa repens,

Tamsulosin, and Serenoa repens plus Tamsulosin treatment for patients

with benign prostate hyperplasia.Int Urol Nephrol. 2007 Jan 4; [Epub ahead

of print]. Department of Urology, Oncology Education and Research

Hospital, Ankara, Turkey. INTRODUCTION: Increasing attention has been

focused on the use of phytotherapeutic agents to alleviate the symptoms of

benign prostatic hyperplasia (BPH) in recent times. The best described and

studied phytotherapeutic agent is Serenoa repens (SR). MATERIALS AND

METHODS: This prospective study was designed to have 3 arms including

SR 320 mg per day (N = 20), Tamsulosin (TAM) 0.4 mg per day (N = 20)

and SR + TAM (N = 20) to reveal the superiority or equivalence between

these treatment regimens in BPH. RESULTS: The groups were not

statistically different with regard to increase in maximal urinary flow rate (Q

(max)) and decrease in International Prostate Symptom Score (I-PSS) (P >

0.05). No adverse effect was detected in SR therapy group. CONCLUSION:

Treatment of BPH by both SR and TAM seems to be effective alone. None

of them had superiority to another and additionally, combined therapy (SR +

TAM) does not provide extra benefits. Furthermore SR is a well-tolerated

agent that can be used alternatively in the treatment of LUTS due to BPH.

PMID: 17203353 [PubMed - as supplied by publisher]

 

Best regards,