Guest guest Posted March 3, 2007 Report Share Posted March 3, 2007 Hi All, See acupuncture abstracts from Medline: Burklein M, Banzer W. | Noninvasive Blood Flow Measurement over Acupuncture Points (GB21): A Pilot Study. | J Altern Complement Med. 2007 Jan;13(1):33-8. | Institute of Sports Sciences, Dept of Sports Medicine, Johann Wolfgang Goethe-Univ, Frankfurt/Main, Germany. | Objective: Noninvasive evaluation of the cutaneous (cBF) and subcutaneous (sBF) blood flow over the AP point (AP) GB21 to assess a characteristically increased microcirculation at AP. Background: AP show several anatomic, histologic and physiologic peculiarities that indicate a specifically elevated microcirculation. Nevertheless cBF and sBF over AP have not yet been established by noninvasive measurements. The laser Doppler spectroscope O2C(©) allows a direct and real-time detection of the local cBF (depth: 1 mm) and sBF (depth: 8 mm) in vivo. Methods: In 28 subjects (41.1+/-9.8 years) the glass fiber probes of the O2C were placed over GB21 and an adjacent asymptomatic reference point (RP) at the Trapezius Muscle. The relative blood flow was measured over a period of 3 minutes in each case. Microcirculation comparisons over AP and RP were made using multivariate analysis of variance. Results: The results showed significantly higher sBF compared to cBF over GB21 (F = 89.95, p< 0.01) and RP (F = 88.47, p< 0.01). A significantly higher microcirculation was evaluated for all subjects over GB21 compared to RP (cBF: F = 7.35, p< 0.05; sBF: F = 8.56, p< 0.01). Conclusion: The employment of the O2C permitted for the first time noninvasive evidence of a significantly increased cBF and sBF over AP (GB21). This evaluation of an initial microcirculatory state of AP should be determined for several AP and larger sampling sizes. The results could be the basis for following controlled AP trials. Regarding a close correlation of AP with myofascial trigger points (TP), further studies in patients with myoskeletal pain could quantify noninvasively a decreased perfusion in the area of TP that might indicate a pathologic condition. The findings of this study encourage the implementation of the laser Doppler spectroscope O2C as a reliable diagnostic tool for various pain syndromes in prevention, therapy, and rehabilitation. | PMID: 17309375 [PubMed - in process] Chen W, Gu HW, Ma WP, Li QS, Yu Q, Liu XQ, Liu SH, Li WH, Liu HL, Dai MT. | [Multicentral randomized controlled study on effects of acupuncture at Zusanli (ST36) and Xuanzhong (GB39) on cerebrovascular function in the patient of ischemic stroke] [Article in Chinese] | Zhongguo Zhen Jiu. 2006 Dec;26(12):851-3. | Hubei Higher Training School of TCM, Jingzhou 434020, China. wenxiao111 | OBJECTIVE: To explore effect of AP at Zusanli (ST36) and Xuanzhong (GB39) on cerebrovascular function in the patient of ischemic stroke. METHODS: Three central, single blind, randomized controlled trial method was adopted, and 160 cases were randomly divided into an AP group and a control group, 80 cases in each group. The two groups were treated by routine treatment for ischemic stroke with AP at Zusanli (ST36) and Xuanzhong (GB39) added in the AP group. Changes of TCD cerebrovascular blood flow indexes before and after treatment were evaluated. RESULTS: After treatment, TCD indexes significantly improved in the AP group (P < 0.05, P < 0.01) with a significant difference as compared with that in the control group (P < 0.05). CONCLUSION: AP at Zusanli (ST36) and Xuanzhong (GB39) can significantly improve cerebral vasomotoricity, cerebral blood flow auto- regulative function, cerebral hemisphere collateral circulation comprehental function in the patient of ischemic stroke. | Publication Types: English Abstract PMID: 17313004 [PubMed - in process] Everke H. | [Preliminary summarization of a new method, extrinsic shock wave acupuncture and moxibustion] [Article in Chinese] | Zhongguo Zhen Jiu. 2006 Dec;26(12):893-5. | Ph. D Heinrich Everke Ambulatorium, Germany. Dr.H.Everke | In medical field, extrinsic shock wave is only used to crush KI stone to pieces. In recent years, a new instrument has been produced, which outputs a more gentle extrinsic shock wave that also can be used for treatment of pain excitation region in the muscular system. This shock wave is called rectilinear ballistic extrinsic shock wave. In 2002, the author designed an instrument, which could generate the rectilinear ballistic extrinsic shock wave and was used at acupoints. The author used the instrument for treatment of over 500 patients and proved that the method had a better effect than that of simple AP and moxibustion for many kinds of diseases. Extrinsic shock wave AP and moxibustion is another method for stimulating acupoints, besides AP, moxibustion, massage of acupoints, Electro-AP and Laser-AP. | Publication Types: English Abstract PMID: 17313015 [PubMed - in process] Fu ZH, Wang JH, Sun JH, Chen XY, Xu JG. | Fu's Subcutaneous Needling: Possible Clinical Evidence of The Subcutaneous Connective Tissue in Acupuncture. | J Altern Complement Med. 2007 Jan;13(1):47-52. | Dept of Anesthesiology, Jinling Hospital, Nanjing Univ, Nanjing, China. | Objectives: Recently it was reported that the loose connective tissue in the subcutaneous layer responded rapidly to mechanical forces evoked by AP, massage, and normal physical movements. However, there were no clinical studies to substantiate these findings so far. Fu's Subcutaneous Needling (FSN) is the innovative needling strategy acting specifically in the subcutaneous layer. A single-blinded and randomized trial was designed to compare the immediate effects of FSN with different needling directions on myofascial trigger points (MTrP) in the neck. Design: For simplicity, we chose two mutually perpendicular needle directions in this study. In one group, the needle was along the local muscle fibers and pointed to the MTrP (Along Group). In the other group, the needle was across the local muscle fibers and also pointed to the MTrP (Across Group). Subjects: Forty- seven (47) patients were randomly divided into two groups: the Along Group (n = 22) and the Across Group (n = 25). There were no significant differences with respect to age, duration of pain, and gender between the two groups. Interventions: FSN needles were inserted and swayed in the subcutaneous layer 200 times in 2 minutes. Results: Before and after FSN treatment, patients were subjected to the assessment of the following three parameters: motion-related pain, pain under pressure, and the range of cervical movement. All three parameters were reduced after the FSN intervention. There were no significant differences in variation of the three parameters between the two groups. Conclusion: Immediate effects of FSN on alleviating MTrP in the neck were not relevant to the needling directions. | PMID: 17309377 [PubMed - in process] Gao J, Fu W, Jin Z, Yu X. | Acupuncture pretreatment protects heart from injury in rats with myocardial ischemia and reperfusion via inhibition of the beta(1)-adrenoceptor signaling pathway. | Life Sci. 2007 Jan 20; [Epub ahead of print] | Dept of Physiology, Institute of Acupuncture, China Academy of Chinese Medical Sciences, PR China. | Our previous study showed that pretreatment with Electro-AP (EA) at bilateral Neiguan acupoints (PC06) had a cardioprotective effect and propranolol diminished the effect of EA; propranolol is a nonspecific antagonist of beta- adrenoceptors (beta-ARs) which are the most powerful cardiac receptors, indicating an involvement of beta-ARs. The present study explored further the signalling mechanism underlying the cardioprotective effect of AP pretreatment in rats subjected to myocardial ischemia and reperfusion (MIR). Myocardial ischemia was achieved by ligating the left anterior descending coronary artery and reperfusion by releasing the ligation. Adult rats were divided into three groups, namely, a normal control (NC) group, a group subjected to ischemia and reperfusion (IR) only, and a group given EA before IR. For EA, bilateral Neiguan points (PC06) of the rats were stimulated for 30 min once/day for 3 consecutive days. The ST segment of ECG, the ratio of infarct size over risk zone, and the contents of beta(1)- adrenoceptor (beta(1)-AR), Gsalpha protein and cAMP in ischemic myocardium were compared among the three groups. IR increased the elevation of ECG ST segment, myocardial infarct size, contents of beta(1)- AR, Gsalpha protein and cAMP. EA pretreatment at bilateral Neiguan acupoints attenuated these effects. The present results indicate that EA has a cardioprotective effect against IR that may be mediated via the beta(1)- AR-Gs-protein-cAMP pathway. | PMID: 17303176 [PubMed - as supplied by publisher] Gibson D, Bruton A, Lewith GT, Mullee M. | Effects of acupuncture as a treatment for hyperventilation syndrome: a pilot, randomized crossover trial. | J Altern Complement Med. 2007 Jan;13(1):39-46. | Physiotherapy Dept, Southampton Univ Hospitals National Health Service Trust, Southampton, Southampton, UK., School of Health Professions and Rehabilitation Sciences, Univ of Southampton, Southampton, UK. | Background: Sustained and subtle hyperventilation can result in a wide variety of symptoms, leading to a chronic condition that has been termed hyperventilation syndrome (HVS). Treatment options include physiotherapy, in the form of breathing retraining (BR), but additional approaches aim to reduce the anxiety that is recognized as being a frequent component of this condition. Objectives: The aim of this study was to evaluate whether AP is an appropriate treatment for HVS to reduce anxiety, and whether a crossover trial is an appropriate study design to evaluate AP in this condition. Design: A single-blind crossover trial was carried out comparing the effects of 4 weeks (30 minutes twice weekly) AP and BR on patients with HVS. Subjects: Ten (10) patients diagnosed with HVS were recruited to the trial and randomized into two groups. Both groups received AP and BR with a washout period of 1 week. Outcome measures: The primary outcome measure used was the Hospital Anxiety and Depression (HAD) Scale. Other outcome measures used were the Nijmegen questionnaire and Medical Research Council Dyspnea scale. Results: The results showed statistically significant treatment differences between AP and breathing retraining, in favor of AP. Reductions were found in the HAD A (anxiety) (p = 0.02) and Nijmegen (symptoms) (p = 0.03) scores. There was no statistical evidence of any carryover effects. However, when graphically examining individual anxiety scores, in those who received AP first, there was a reduction in anxiety levels which persisted through the washout period, suggesting that there may have been some carryover effect from this treatment. Conclusions: This study suggests that AP may be beneficial in the management of HVS in terms of reducing anxiety levels and symptom severity. However, there may be some carryover effect, after AP treatment, which went undetected because the small sample size. This preliminary study provides the basis for a larger, sufficiently powered and methodologically sound trial. | PMID: 17309376 [PubMed - in process] He QY, Zhang J. | [Professor ZHANG Ji's clinical experience] [Article in Chinese] | Zhongguo Zhen Jiu. 2006 Dec;26(12):890-2. | College of Acupuncture and Moxibustion, Beijing Univ of TCM, Beijing 100029, China. heqingyong | Professor ZHANG Ji has unique experience on therapeutic methods for rheumatoid arthritis, ankylosing spondylitis and obstinate facial palsy. (1) In AP and moxibustion, he adopts the Dumai (GV) and etiological analysis and differentiation, local AP three step acupoint selection for treatment of rheumatoid arthritis; and supplementing LV & KI and strengthening the GV and tonifying Yang for ankylosing spondylitis; and dispelling Wind and removing Damp, dredging Channels and activating Collaterals for obstinate facial palsy. (2) In Chinese drugs, on the basis of 50 year's clinical practice, he summarizes recipes Guanjie No. I and No. II. Modified Guanjie No. I is mainly used for treatment of rheumatoid arthritis, and modified Guanjie No. II mainly for ankylosing spondylitis, and Qianzheng Powder combined with drugs for clearing away heat and toxic substances are used for treatment of obstinate facial palsy. | Publication Types: English Abstract PMID: 17313014 [PubMed - in process] Hou LQ, Xiong KR. | [Effect of different needle-retained time of electroacupuncture on expression of nitric oxide synthase in the septum of the rat] [Article in Chinese] | Zhongguo Zhen Jiu. 2006 Dec;26(12):879-82. | Dept of Anatomy, Wannan Medical College, Wuhu, Anhui 241001, China. | OBJECTIVE: To probe into the relationship of different needle-retained time with therapeutic effects. METHODS: 40 rats were randomized evenly into 5 groups, Electro-AP (EA) at " Zusanli " (ST36) for 5 min, 15 min, 30 min and 60 min groups, who received EA for 5, 15, 30 and 60 min respectively, and a control group who did not receive EA. Nicotinamide adenosine dinucleotide phosphate diaphorase (NADPH-d) method and computer image analysis system were used to detect the meangray of nitric oxide synthase (NOS) positive neurons in the septum. RESULTS: NOS positive neurons in the septum did not change as the EA for 5 min group compared with the control group (P > 0.05); the number of heavily staining NOS positive neurons increased significantly (P < 0.05) and the meangray of the NOS positive neurons significantly decreased (P < 0.01) in some septal subnuclei (lateral septum, and medial septum, vertical diagnonal band) after EA for 15, 30, 60 min as compared with the control group, and the numbers and the meangray of the NOS positive neurons in the septum were not significantly difference among the 3 EA groups. CONCLUSION: NOS expression in the septum increases and keeps a same level from EA for 15 min to 60 min. | Publication Types: English Abstract PMID: 17313012 [PubMed - in process] Huang CL, Tsai PS, Wang TY, Yan LP, Xu HZ, Huang CJ. | Acupuncture stimulation of ST36 (Zusanli) attenuates acute renal but not hepatic injury in lipopolysaccharide-stimulated rats. | Anesth Analg. 2007 Mar;104(3):646- 54. | Acupuncture and Moxibustion Institute, Nanjing Univ of Traditional , Nanjing, China. | BACKGROUND: We sought to determine the effects of ST36 AP on sepsis-induced KI and LV injuries. METHODS: A total of 120 rats were randomized into 10 groups: 1) lipopolysaccharide (LPS), 2) normal saline (N/S), 3) LPS + ST36, 4) ST36, 5) LPS + P-ST36, 6) P-ST36, 7) LPS + Sham, 8) Sham, 9) LPS + P-Sham, and 10) P-Sham groups. Rats in the LPS + ST36, ST36, LPS +Sham, and Sham groups received ST36 (designated as " ST36 " ) or a nonacupoint (designated as " Sham " ) AP for 30 min followed by LPS or N/S injection. Rats in the LPS + P-ST36, P-ST36, LPS + P-Sham, and P-Sham groups received LPS or N/S injection for 3 h followed by a 30 min of ST36 or a " nonacupoint " AP. Rats were killed at 6 h after LPS injection. RESULTS: LPS caused prominent KI and LV injuries. The renal and hepatic nitric oxide (NO) concentrations and inducible NO synthase (iNOS) expression were also increased by LPS. ST36 AP pretreatment significantly attenuated the LPS-induced KI injury and the increases in renal NO concentration and iNOS expression. However, ST36 AP pretreatment did not affect the LPS- induced LV injury and increases in hepatic NO concentration or iNOS expression. Furthermore, ST36 AP performed after LPS did not affect the LPS-induced organ injuries or increases in NO concentration and iNOS expression. CONCLUSIONS: ST36 AP pretreatment significantly attenuated sepsis-induced KI, but not LV, injury in rats, whereas ST36 AP performed after sepsis induction had no protective effects against sepsis-induced organ injuries. | Publication Types: Research Support, Non-U.S. Gov't PMID: 17312224 [PubMed - in process] Huang DE, Wu Q, Lin ZR, Lin D, Shen FF, Liu JZ. | [Effects of different interference orders of acupuncture and exercise therapy on the amplitude of somatosensory evoked potential (SEP) in the patient of hemiplegia after stroke] [Article in Chinese] | Zhongguo Zhen Jiu. 2006 Dec;26(12):869-72. | Dept of TCM, Fuzhou General Hospital, Nanjing Military Area, Fujian 350025, China. | OBJECTIVE: To observe effects of different interference orders of AP and exercise therapy on the therapeutic effect. METHODS: The patients of hemiplegia after stroke in the stage of recovery were randomly divided into two groups: raising handclasp of Bobath after Electro- AP at Quchi (LI11) and Hegu (LI04) on the affected side or Electro-AP at Quchi (LI11) and Hegu (LI04) on the affected side after raising handclasp of Bobath. The changes of SEP on the affected side were recorded and compared. RESULTS: SEP on the affected side significantly increased in the patients after treatment of simple Electro-AP or exercise therapy (P < 0.01), with no significant difference between the two groups (P > 0.05). There was a very significant difference in SEP on the affected side between the group of exercise treatment after Electro-AP and the group of Electro- AP after exercise therapy (P < 0.01). CONCLUSION: Both Electro-AP and exercise therapy can immediately improve SEP of the patient in the recovery stage, and the groups of the different interference orders of Electro-AP and exercise have different effects on SEP, and raising handclasp of Bobath after Electro-AP is better for improvement in cerebral function of the patient. | Publication Types: English Abstract PMID: 17313010 [PubMed - in process] Kawakita K, Okada K. | Mechanisms of action of acupuncture for chronic pain relief - polymodal receptors are the key candidates. | Acupunct Med. 2006 Dec;24 Suppl:S58-66. | | Therapeutic benefits of AP for chronic pain patients have been clearly identified in recent clinical trials. Underlying mechanisms of AP action mediated by endogenous opioids have been well demonstrated. The existence of pain inhibitory systems in the central nervous system has also been clarified and AP seems to be a potent stimulus for activating the analgesic systems, although the pain mechanisms in acute and chronic states are essentially different. On the other hand, the exact nature of the AP point still remains unclear. Here, we propose a key role of polymodal receptors (PMR) in AP and moxibustion and offer a rational explanation of the AP point as a sensitised PMR. Moxibustion (burning of moxa) therapy has been shown by medical historians to predate the use of AP, and the meridian theory developed in association with moxibustion treatment. A variety of sensory receptors are activated by AP and/or moxibustion, but there are very few that can be excited by both stimuli. PMRs are one of the most promising candidates. The functional characteristics of PMRs correspond with those of AP action in the periphery; and tender or trigger points, one of the primitive features of AP points, are assumed to be the sites of sensitised PMRs. Diffuse noxious inhibitory control (DNIC) is proposed as a possible mechanism of immediate action of AP, and inputs for the development of DNIC seem to be the PMRs. In our experimental model, repeated eccentric contractions of muscle produced local tenderness at the palpable band and induced a typical referred pain pattern on application of pressure. Repeated indomethacin injections inhibited the production of the experimental trigger point. These lines of evidence suggest that the AP points are the sites where the PMRs are sensitised and that such conditions might be repeatedly produced by various biomechanical stressors, insufficient blood supply and metabolic products. | PMID: 17308511 [PubMed - in process] Li SL, Bai Y, Li H, Zhang YW. | [Preliminary evaluation of acupuncture and continuous multi-point pulse stimulation for treatment of subjective tinnitus] [Article in Chinese] | Zhongguo Zhen Jiu. 2006 Dec;26(12):859-62. | Dept of Acupuncture and Moxibustion, China-Japan Friendship Hospital, Beijing 100029, China. zrlishiliang | OBJECTIVE: To put forward a method for assessing therapeutic effect on tinnitus and to observe the therapeutic effects of AP and continuous multi-point pulse stimulation on subjective tinnitus. METHODS: Continuous multi-point pulse stimulation was given at Ermen (SJ21)/ Tinggong (SI 19)/ Tinghui (GB02), Yifeng (SJ17), Shenting (GV24), Baihui (GV20), Cong'er No 1-3, etc., once every other day, thrice each week. The therapeutic effects were evaluated with a selfstipulated " tinnitus questionaire " . RESULTS: Of the 98 cases, 11 cases were cured, 36 cases were markedly effective, 28 cases were effective and 23 cases were ineffective with a cured rate of 11.2% and a total effective rate of 76.5%. CONCLUSION: Combined AP and continuous multi-point pulse stimulation has a better therapeutic effect on subjective tinnitus. | Publication Types: English Abstract PMID: 17313007 [PubMed - in process] Linde K, Streng A, Hoppe A, Jurgens S, Weidenhammer W, Melchart D. | The programme for the evaluation of patient care with acupuncture (PEP- Ac) - a project sponsored by ten German social health insurance funds. | Acupunct Med. 2006 Dec;24 Suppl:S25-32. | | OBJECTIVE: The aim of the Programme for the Evaluation of Patient care with AP (PEP-Ac) was to investigate the efficacy, effectiveness and safety of AP in patients with the following three indications: chronic headache, chronic low back pain and chronic osteoarthritic pain. This article provides an overview of the results of the whole programme. METHODS: The programme included five randomised trials, a large observational study, a survey of physicians providing AP, and three systematic reviews. RESULTS: The results show that, for all three indications, AP, when compared to no treatment, produces a clear benefit that lasts for at least several months. However the effects of point-specific AP only offered a significant advantage over minimal AP in the treatment of OA knee. CONCLUSIONS: The evidence from these trials - on the one hand, a clear overall effect of AP and on the other hand, the lack of evidence supporting its superiority over sham AP for all indications except osteoarthritis of the knee - leaves a considerable amount of room for interpretation. | PMID: 17308506 [PubMed - in process] Liou JT, Liu FC, Hsin ST, Sum DC, Lui PW. | Broken needle in the cervical spine: a previously unreported complication of xiaozendao acupuncture therapy. | J Altern Complement Med. 2007 Jan;13(1):129-32. | Dept of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan., Chang Gung Univ, Taoyuan, Taiwan. | Xiaozendao (meaning " small-needle-knife, " in Chinese) is a form of alternative medical instrument shaped like an AP needle with a flat edge on the needle tip. It is widely used for the treatment of many different disorders in Asian countries, especially in the People's Republic of China. Its use has gained increasing popularity. To our knowledge, there are no reports of practitioners' experiences or adverse events related to " small-needle-knifed " therapy until now. We reported the first case of spinal-cord injury with delayed onset of neurologic symptoms from a broken small-needle-knife insertion into the spinal cord. | PMID: 17309387 [PubMed - in process] Lu W, Hu D, Dean-Clower E, Doherty-Gilman A, Legedza AT, Lee H, Matulonis U, Rosenthal DS. | Acupuncture for chemotherapy-induced leukopenia: exploratory meta-analysis of randomized controlled trials. | J Soc Integr Oncol. 2007 Winter;5(1):1-10. | | Chemotherapy-induced leukopenia and neutropenia are common side effects during cancer treatment. AP has been reported as an adjunct therapy for this complication. The current study reviewed published randomized controlled trials of AP's effect and explored the AP parameters used in these trials. We searched biomedical databases in English and Chinese from 1979 to 2004. The study populations were cancer patients who were undergoing or had just completed chemotherapy or chemoradiotherapy, randomized to either AP therapy or usual care. The methodologic quality of trials was assessed. From 33 reviewed articles, 682 patients from 11 eligible trials were included in analyses. All trials were published in non-PubMed journals from China. The methodologic quality of these trials was considerably poor. The median sample size of each comparison group was 45, and the median trial duration was 21 days. The frequency of AP treatment was once a day, with a median of 16 sessions in each trial. In the seven trials in which white blood cell (WBC) counts were available, AP use was associated with an increase in leukocytes in patients during chemotherapy or chemoradiotherapy, with a weighted mean difference of 1,221 WBC/muL on average (95% confidence interval 636-1,807; p < .0001). AP for chemotherapy-induced leukopenia is an intriguing clinical question. However, the inferior quality and publication bias present in these studies may lead to a false-positive estimation. Meta-analysis based on these published trials should be treated in an exploratory nature only. | PMID: 17309808 [PubMed - in process] Lundeberg T. | Some of the effects of acupuncture in knee pain may be due to activation of the reward system. | Acupunct Med. 2006 Dec;24 Suppl:S67-70. | | AP is an ancient therapy with a variety of different explanatory models. A cascade of physiologic effects has been reported, both in the peripheral and the central nervous system, following the insertion of a needle. Clinical trials testing the specific claims of AP have generally tried to focus on testing the efficacy of applying specific techniques and/or specified points. However, different conditions may respond differently to different modes of stimulation. Also, insertion of needles into the body can stimulate effects not dependent on the locations of stimulation. Recently, it was demonstrated that both superficial and deep needling (with de qi/Hibiki) resulted in amelioration of patellofemoral pain and an increased feeling of wellbeing. One area in the brain that is affected by AP stimulation is the limbic system. The limbic system consists of a group of brain structures, including the hippocampus, amygdala, and their interconnections, and connections with the hypothalamus, septal area, and portions of the tegmentum. It contains many of the centres related to emotion and reward. The pleasurable aspect of the AP experience has largely been ignored as it has been considered to be part of its antinociceptive effects. It has previously been reported that physical exercise and Electro-AP in animals result in modulation of the peptidergic content in limbic structures. These results are supported by recent animal studies in Japan that have clearly demonstrated that AP results in the activation of the reward system. These findings are supported by positron emission tomography studies in patients, which showed that the insula ipsilateral to the site of needling was activated, as well as the dorsolateral prefrontal cortex, the anterior cingulate and the midbrain. Taken together, these results suggest that AP, as well as the patient's expectation and belief regarding a potentially beneficial treatment, modulate activity in the reward system. | PMID: 17308512 [PubMed - in process] Manheimer E, Lim B, Lao L, Berman B. | Acupuncture for knee osteoarthritis - a randomised trial using a novel sham. | Acupunct Med. 2006 Dec;24 Suppl:S7-14. | | BACKGROUND: Evidence on the efficacy of AP for reducing the pain and dysfunction of osteoarthritis is equivocal. OBJECTIVE: To determine whether AP provides greater pain relief and improved function compared with sham AP or education in patients with osteoarthritis of the knee. DESIGN: Randomised, controlled trial. SETTING: Two outpatient clinics (an integrative medicine facility and a rheumatology facility) located in academic teaching hospitals and one clinical trials facility. PATIENTS: 570 patients with osteoarthritis of the knee (mean age [+/-SD], 65.5 +/- 8.4 years). INTERVENTION: 23 true AP sessions over 26 weeks. Controls received 6 two-hour sessions over 12 weeks or 23 sham AP sessions over 26 weeks. MEASUREMENTS: Primary outcomes were changes in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain and function scores at 8 and 26 weeks. Secondary outcomes were patient global assessment, 6-minute walk distance, and physical health scores of the 36-Item Short-Form Health Survey (SF-36). RESULTS: Participants in the true AP group experienced greater improvement in WOMAC function scores than the sham AP group at 8 weeks (mean difference, -2.9 [95% CI, -5.0 to -0.8]; P=0.01) but not in WOMAC pain score (mean difference, -0.5 [CI, -1.2 to 0.2]; P=0.18) or the patient global assessment (mean difference, 0.16 [CI, -0.02 to 0.34]; P> 0.2). At 26 weeks, the true AP group experienced significantly greater improvement than the sham group in the WOMAC function score (mean difference, -2.5 [CI, -4.7 to -0.4]; P=0.01), WOMAC pain score (mean difference, -0.87 [CI, -1.58 to -0.16]; P=0.003), and patient global assessment (mean difference, 0.26 [CI, 0.07 to 0.45]; P=0.02). LIMITATIONS: At 26 weeks, 43% of the participants in the education group and 25% in each of the true and sham AP groups were not available for analysis. CONCLUSIONS: AP seems to provide improvement in function and pain relief as an adjunctive therapy for osteoarthritis of the knee when compared with credible sham AP and education control groups. | PMID: 17308513 [PubMed - in process] Michalek-Sauberer A, Heinzl H, Sator-Katzenschlager SM, Monov G, Knolle E, Kress HG. | Perioperative auricular electroacupuncture has no effect on pain and analgesic consumption after third molar tooth extraction. | Anesth Analg. 2007 Mar;104(3):542-7. | Dept of Anesthesiology and General Intensive Care Medicine (B), Medical Univ of Vienna, Vienna General Hospital, Vienna, Austria. andrea.michalek-sauberer | BACKGROUND: Auricular AP (AA) has been shown to alleviate acute and chronic pain. We investigated the effects of auricular Electro-AP (AE) on pain and analgesic drug consumption in the first 48 h after unilateral mandibular third molar tooth extraction under local anesthesia in a prospective, randomized, double-blind, placebo-controlled study in 149 patients. METHODS: Patients received either AA with electrical stimulation (AE, n = 76) or without (AA, n = 37) electrical stimulation at an alternating frequency of 2/100 Hz or a sham AE with metal plates instead of needles and no electrical stimulation, no-needle (NN, n = 36) at the AA points 1 (tooth), 55 (Shen men) and 84 (mouth) during the entire study period. Regularly rated pain intensity (five-point verbal rating scale), consumption of acetaminophen 500 mg tablets and additional rescue medication with mefenamic acid 500 mg were assessed. RESULTS: The median fraction of time when pain was rated as moderate or worse (upper and lower quartile): AE: 33% (12%, 64%), AA: 22% (6%, 56%), NN: 30% (7%, 53%) did not differ significantly among the treatment groups. There were no significant differences in mean number of acetaminophen 500 mg tablets (range): AE: 5.2 (0-12), AA: 4.6 (0-11), NN: 5.4 (0-10) or percentage of patients requiring additional mefenamic acid: AE: 19%, AA: 18%, NN: 19%. CONCLUSION: We conclude that neither AE nor AA alone reduce either pain intensity or analgesic consumption in a molar tooth extraction model of acute pain. | PMID: 17312205 [PubMed - in process] Sun YZ, Chen HL. | [Controlled study on Shu-Mu point combination for treatment of endometriosis] [Article in Chinese] | Zhongguo Zhen Jiu. 2006 Dec;26(12):863-5. | The 4th Internal Medicine Ward, The Second Affiliated Hospital, Heilongjiang Traditional Univ, Harbin 150001, China. sunyuanzheng | OBJECTIVE: To compare therapeutic effects of Shu-Mu point combination, routine needling method and western medicine treatment on endometriosis (EM). METHODS: Ninety cases were randomly divided into a Shu-Mu point combination group (n = 30) treated with AP at Ganshu (BL18), Pishu (BL20), Shenshu (BL23), Qimen (LV14), Zhangmen (LV13), Jingmen (GB25); a routine needling group (n = 30) treated with AP at Hegu (LI04), Zhongji (CV03), Guanyuan (CV04), Sanyinjiao (SP06) and a western medicine group treated with oral administration of Danazol. Clinical symptoms and signs, tumor marker serum CA125 values and adverse effects in the three groups were investigated before and after treatment. RESULTS: The total effective rate was similar in the three groups. The Shu-Mu point combination group was superior to other two groups in improvement of dysmenorrhea, irregular menstuation, lumbago and sacrodynia, anus engorgemant, etc. (P < 0.01). After treatment, serum CA125 decreased significantly (P < 0.01) in the Shu- Mu point combination group. CONCLUSION: Shu-Mu point combination needling method has an obvious therapeutic effect on endometriosis, with lower adverse effect than that of the western medicine group. | Publication Types: English Abstract PMID: 17313008 [PubMed - in process] Vas J, Mendez C, Perea-Milla E. | Acupuncture vs Streitberger needle in knee osteoarthritis - an RCT. | Acupunct Med. 2006 Dec;24 Suppl:S15-24. | | AIMS: To determine the effectiveness of AP as a therapy complementary to the pharmacological treatment of osteoarthritis of the knee. METHODS: Randomised, single blind, placebo controlled trial. Patients with osteoarthritis of the knee were randomly assigned to either 12 sessions of true AP or 12 sessions of placebo AP (Streitberger needle), these sessions taking place once a week. A baseline measurement was carried out, followed by further observations at 4, 8, 12 and 16 weeks. The clinical variables were the WOMAC (Western Ontario and McMaster Universities Osteoarthritis) index, knee pain measured by a visual analogue scale (pain VAS), the weekly consumption of diclofenac and the Profile of the Quality of Life of the Chronically Ill (PQLC). The two groups were compared for each of the clinical variables per protocol and by intention to treat. A multiple linear regression model for the dependent variables was constructed. RESULTS: Ninety seven outpatients were selected, with 88 remaining for the per protocol analysis; the analysis of homogeneity concluded that the lost subjects were not significantly different from those that completed the study. The multivariate per protocol model for the relative pain VAS variable showed a difference in improvement of 43.7% (95% CI 29.4% to 58.0%) for AP, compared with the control group. In an intention to treat analysis, the relative improvement was 32.4% (20.3% to 44.4%). In a per protocol analysis, the total WOMAC showed a relative decrease of 52.0% (34.3% to 69.6%) in favour of the AP group, or 37.6% (22.4% to 52.8%) in an intention to treat analysis. CONCLUSIONS: The group treated with AP showed significantly better effects, both clinically and statistically, in the reduction of pain intensity as measured by pain VAS, on the WOMAC index and in decreased consumption of diclofenac. | PMID: 17308505 [PubMed - in process] Wang B, Liu JY, Han Y, Zhang N, Ren XQ, Zhai GR, Pan JF, Wang Y, Zhou Y. | [study on effect of electroacupuncture at Hegu (LI04) on the uterotonic time in parturients of uterus inertia] [Article in Chinese] | Zhongguo Zhen Jiu. 2006 Dec;26(12):843-6. | Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China. | OBJECTIVE: To evaluate the therapeutic effect and applying value of Hegu (LI04) for uterus inertia. METHODS: In three centers, 276 cases enrolled were randomly assigned to a western medicine group and an AP and western medicine group. The western medicine group were treated with intravenous drip of oxytocin, and the AP and western medicine group were treated with Electro-AP at Hegu (LI04) and intravenous drip of oxytocin. Changes of inertia of uterus and duration and interval of uterine contraction were investigated in the two groups. RESULTS: The total effective rate was 97.1% in the AP group, and 70.3% in the western medicine group with a very significant difference between the two groups (P < 0. 01). There was a significant difference in the duration and the interval of uterine contraction between the two groups (P < 0.1, P < 0.05). CONCLUSION: Electro-AP at Hego (LI04) can be adopted for treatment of dystocia due to abnormality of force of labor. | Publication Types: English Abstract PMID: 17313002 [PubMed - in process] Wang XY. | [Effects of different stimulation intensities on hemotachogram of the limbs of pain arthralgia] [Article in Chinese] | Zhongguo Zhen Jiu. 2006 Dec;26(12):866-8. | The Second Hospital of Jilin Univ, Changchun 130041, China. wangxiaoyan410 | OBJECTIVE: To study on the relationship between AP stimulating amount and hemotachogram in the limbs of pain arthralgia. METHODS: Forty-one cases of pain arthralgia of the lower limbs with cold pathogen as main were selected. After AP and arrival of qi, twirling manipulation with a strong and a weak stimulating intensities respectively given to a same person. Then hemotachogram of the affected limb was investigated and the amplitudes were calculated and compared. RESULTS: After strong stimulation of AP, the amplitude decreased and after weak stimulation, the amplitude increased. CONCLUSION: Different stimulating amount of AP can induce different responses of vasomotorial functions of the affected limbs. | Publication Types: English Abstract PMID: 17313009 [PubMed - in process] White A, Foster N, Cummings M, Barlas P. | The effectiveness of acupuncture for osteoarthritis of the knee - a systematic review. | Acupunct Med. 2006 Dec;24 Suppl:S40-48. | | OBJECTIVE: To determine the effectiveness of AP treatment for pain and function of patients with osteoarthritis of the knee. METHODS: A systematic review of randomised controlled trials was performed, including a meta-analysis which combined the results of trials that used adequate AP treatment and used WOMAC scores to measure the effect. The internal validity (quality) and heterogeneity of studies were taken into account. RESULTS: Thirteen studies were available, of which eight, involving 2362 patients, could be combined. For both reduction of pain and improvement of function, AP was significantly superior to sham AP (P<0.05 for all comparisons) in both the short term and the long term. Compared with no additional intervention (usual care), AP was again significantly superior for pain and function. The treatment effects were maintained after taking account of quality and heterogeneity in sensitivity analyses. CONCLUSION: AP is an effective treatment for osteoarthritis of the knee. Its overall effect size is 0.8, and it can be considered instead of non-steroidal anti-inflammatory drugs for patients whose symptoms are not controlled by education, exercise, weight loss if appropriate and simple analgesics. Further research is necessary into the most efficient way of delivering AP, and its longer term benefits. | PMID: 17308508 [PubMed - in process] White A, Kawakita K. | The evidence on acupuncture for knee osteoarthritis - editorial summary on the implications for health policy. | Acupunct Med. 2006 Dec;24 Suppl:S71-76. | | Decisions on whether a health service should provide a particular treatment are based on the evidence on three questions: 1) whether the treatment can work, ie it is biologically active; 2) whether the treatment is safe and effective in daily practice; and 3) whether it is economically worthwhile. Evidence presented at the Kyoto conference shows that AP for osteoarthritis of the knee has a biological effect, has a large clinical effect in practice, has negligible risk, and has a cost effectiveness which is well within the usual acceptable limit. On the present evidence, AP is likely to offer an alternative to treatment with non-steroidal anti-inflammatory drugs (NSAIDs). | PMID: 17308514 [PubMed - in process] White A. | The safety of acupuncture - evidence from the UK. | Acupunct Med. 2006 Dec;24 Suppl:S53-57. | | BACKGROUND: Patients are attracted to AP partly by its reputation for having low risks. The safety of AP should be established by positive evidence. METHODS: Two prospective surveys were conducted among different groups of professionals in the UK, including doctors, physiotherapists and practitioners primarily trained in AP. Participants monitored adverse events over a defined period of time, and reported minor and significant events on purpose designed forms. RESULTS: A total of 652 acupuncturists reported 6733 adverse reactions including tiredness in 66 229 patients, an adverse event rate of 10.2%. The most common events were tiredness (3%) bleeding or bruising (3%), aggravation of symptoms (2%) and pain at the needling site (1%). There were no serious adverse events. A total of 86 (0.1%) of the treatments was associated with an event that the practitioner judged to be significant though without persistent consequences for the patient's health. CONCLUSION: The risks associated with AP can be classified as negligible, and AP is a very safe treatment in the hands of competent practitioners. | PMID: 17308510 [PubMed - in process] White A. | Osteoarthritis of the knee - an introduction. | Acupunct Med. 2006 Dec;24 Suppl:S1-6. | | Osteoarthritis of the knee is common, and a major cause of disability in older people that is likely to increase over time. Some patients progress rapidly to needing surgery, whereas others will have persistent pain for many years. The aims of conservative treatment are to reduce pain and disability. There is evidence that several non- pharmacological therapies such as exercise, education and weight loss can have an effect in patients with knee pain, though the effect is usually only modest. Ultrasound and short wave diathermy are widely available, but not supported by evidence. Particular preparations of topical treatments are effective, as too is oral paracetamol (acetaminophen). Glucosamine is popular but not all trials have found it to have any effect. Non-steroidal anti- inflammatory drugs (NSAIDs) are effective, though their effect is modest and their longterm value is not established. They are associated with significant adverse events, particularly gastrointestinal haemorrhage, which has a substantial mortality. They are particularly dangerous in the elderly. Cyclooxygenase-2 (COX-2) inhibitors cause fewer gastrointestinal problems but increase the risk of vascular events including myocardial infarction and stroke. Herbal therapies have only sparse evidence in support. Intra- articular injections of steroids may be effective, at least for a short period, but hyaluronan has a longer duration of action. Patients prefer treatments that are safe, and are willing to forgo some effectiveness in favour of safety. In this context, AP is a potentially valuable treatment for OA knee, and the evidence on effectiveness, safety and cost should be considered carefully. | PMID: 17308504 [PubMed - in process] Wick F, Wick N, Wick MC. | Morphological analysis of human acupuncture points through immunohistochemistry. | Am J Phys Med Rehabil. 2007 Jan;86(1):7-11. | Clinical Depts of Physical Medicine and Rehabilitation, Univ of Vienna, Vienna, Austria. | OBJECTIVE: At present, the functional mechanism of AP is not yet fully understood. Analysis of the subanatomic morphology of AP points (APs) could help compensate for this shortcoming. In immunohistochemistry, the use of specific antibodies enables in situ characterization of the molecular profile of tissue microenvironments. Thus, as proof in principle for the utility of immunohistochemistry, we determined whether the nerve density in biopsies of autopsied skin of a selected standard AP differed from that of a control point (CP). DESIGN: We analyzed pairs of skin samples from nine autopsy cases and studied the presence and density of soluble protein 100 (S-100), neuron-specific enolase (NSE), and neurofilament (NF) as markers of peripheral nerve structures. Cross-sections of nerves were counted by conventional microscopy and normalized to millimeters squared of subcutaneous fat, followed by statistical analyses for formal comparisons. RESULTS: Immunohistochemistry could clearly identify myelinated peripheral nerves. The number of nerve structures expressing S-100 protein was significantly reduced in APs compared with CPs (0.020 1 0.005 vs. 0.061 +/- 0.014; P < 0.006). The same pattern was seen in staining of NSE (AP: 0.011 +/- 0.003 vs. CP: 0.045 +/- 0.011) and NF (AP: 0.011 +/- 0.004 vs. CP: 0.054 +/- 0.015; both P < 0.007). CONCLUSIONS: In this study, we introduce immunohistochemistry as a suitable technology for AP research. In addition, our findings demonstrate that a human AP is not necessarily associated with an increased but, rather, a significantly decreased number and density of subcutaneous nerve structures compared with skin biopsies from locations not recognized as effective for AP. This pilot study, executed on a limited number of individuals and skin samples, justifies the application of immunohistochemistry on a larger collection of biopsy material. | Publication Types: Research Support, Non-U.S. Gov't PMID: 17304683 [PubMed - in process] Witt CM, Brinkhaus B, Reinhold T, Willich SN. | Efficacy, effectiveness, safety and costs of acupuncture for chronic pain - results of a large research initiative. | Acupunct Med. 2006 Dec;24 Suppl:S33-39. | | BACKGROUND: The aim of the 'AP Model Project of the Techniker Krankenkasse' was to determine efficacy, effectiveness, safety and cost effectiveness of AP treatment in standard medical care. METHODS: We evaluated a total of 304 674 patients (34.5% men, aged 53.1+/-13.8 and 65.5% women, aged 49.5+/-14.2) who were in the care of over 10 000 physicians and received on average 10+/-3 AP treatments for chronic pain (osteoarthritis of the hip or knee, low back pain, neck pain, headache) during a period of three months. RESULTS AND CONCLUSIONS: Our findings demonstrate that for the diagnoses examined, AP in addition to usual care was an effective and safe treatment. Whether the effects of AP can be attributed primarily to specific or nonspecific mechanisms appeared to depend on the diagnosis, and should be investigated in further studies. Using AP as an adjunctive treatment was more expensive than usual care alone, but was cost-effective according to internationally accepted threshold values. | PMID: 17308507 [PubMed - in process] Wu RD, Lin LF. | [Clinical observation on wrist-ankle acupuncture for treatment of paroxysmal supraventricular tachycardia] [Article in Chinese] | Zhongguo Zhen Jiu. 2006 Dec;26(12):854-6. | Dept of TCM, Yongchun Hospital of Quanzhou City, Fujian 362600, China. qylicb | OBJECTIVE: To observe the therapeutic effect and prognosis of wrist-ankle AP for treatment of paroxysmal supraventricular tachycardia. METHODS: Ninety-five cases of paroxysmal supraventricular tachycardia were randomly divided into a wrist-ankle AP group (n = 55) and a control group (n = 40). The treatment group were treated with AP at the points, Wanshang No. 1 and 2, and the control group with oral administration of diltiazem. After being treated for 3 courses, their therapeutic effects were evaluated. RESULTS: The total effective rate was 81.8% in the treatment group and 54.0% in the control group with a significant difference between the two groups (P < 0. 05); the long-term therapeutic effect in the treatment group was better than that in the control group. CONCLUSION: Wrist-Ankle AP has obvious therapeutic effect on paroxysmal supraventricular tachycardia. | Publication Types: English Abstract PMID: 17313005 [PubMed - in process] Yamashita H, Masuyama S, Otsuki K, Tsukayama H. | Safety of acupuncture for osteoarthritis of the knee - a review of randomised controlled trials, focusing on specific reactions to acupuncture. | Acupunct Med. 2006 Dec;24 Suppl:S49-52. | | In order to assess how many reported adverse reactions to AP are truly associated with the physiological mechanisms of AP, we performed a literature review of published RCTs of AP for osteoarthritis of the knee. We searched for reports of RCTs using two data sources: PubMed and Japana Centra Revuo Medicina (Igaku Chuo Zasshi). Of the twelve RCTs located, seven included information on adverse events. No serious adverse events were reported. Joint swelling, local inflammation, haematoma and back pain occurred more frequently in the dummy Electro-AP or minimal AP group. We confirmed the possibility that many adverse reactions to AP treatment reported in RCTs, at least for the knee OA, are non-specific, and that not all reported events should be attributed to the mechanism of action of AP. It is likely this is also true for RCTs of AP in other conditions, and for prospective surveys on adverse events of AP. | PMID: 17308509 [PubMed - in process] Yang J, Li F, Zhang QP, Wang KM, Hong W, Wu SB, Zhou YP. | [Effect of electroacupuncture combined with medication on vascular endothelial cells in the compound hypertension and hyperlipemia rat] [Article in Chinese] | Zhongguo Zhen Jiu. 2006 Dec;26(12):875-8. | Acupuncture Hospital Affiliated to Anhui College of TCM, Hefei 230061, China. yangzyun | OBJECTIVE: To explore the mechanism of Electro-AP combined with medication for treatment of compound model of hypertension and hyperlipemia (CMHH). METHODS: CMHH rat model was made by the way of " 2K1C " combined with intragastric perfusion of high fat diet, and a normal group and a pseudosurgery group were set up. After modeling for 4 weeks, the successful model rats who had synchronously increase of blood pressure (BP) and blood lipids were randomly divided into a model group, a medication group , an Electro-AP group and an AP plus medication group. After interference of 4 weeks, changes of BP, total cholesterol (TC) and thiglyceride (TG) and contents of serum vWF, tissue plasminogen activator (t-PA ) and plasminogen activator inhibitor-1 (PAl-1) were observed. RESULTS: After interference, the levels of BP, TC, TG, vWF, t-PA and PAl-1 significantly changed in all the treatment groups as compared with those in the model group (P < 0.05 or P < 0.01) with most significantly changed in the Electro-AP plus medication group. CONCLUSION: Both Electro-AP and Electro-AP + medication can down- regulate levels of BP, TC, TG, and decrease plasma vWF and PAl-1 levels, increase t-PA content, so as to effectively prevent and treat CMHH and possibly induced cerebral diseases. | Publication Types: English Abstract PMID: 17313011 [PubMed - in process] Zhang ZL, Ji XQ, Zhang YH, Yu SH, Xue L. | [Controlled study on the needling method for regulating the spleen and stomach for treatment of diabetic retinopathy] [Article in Chinese] | Zhongguo Zhen Jiu. 2006 Dec;26(12):839-42. | Section of Acupuncture and Moxibustion, Tianjin Hospital of TCM, Tianjin 300140, China. zhangzilongtj | OBJECTIVE: To probe clinical therapeutic effect of AP on diabetic retinopathy and the mechanism. METHODS: One hundred and twenty cases of diabetic retinopathy were randomly divided into an observed group and a control group, 60 cases in each group. On the basis of routine diabetic treatment, the observation group were treated with the acupoints for regulating the SP and ST, and the control group with the acupoints around eye mainly. Clinical therapeutic effect was evaluated by eye fundus condition, blood glucose, blood lipids, nitric oxide (NO) and endothelin (ET) levels. RESULTS: The needling method for regulating the SP and ST not only can improve the eye fundus condition, but also has benign regulative action on metabolism of blood glucose and blood lipids, and NO and ET levels, with significant differences as compared with those in the control group (P < 0.05, P < 0.01). CONCLUSION: The needling method for regulating the SP and ST is an effective therapy for diabetic retinopathy, and the mechanism is possibly related with the regulation of levels of vascular active substances, NO and ET. | Publication Types: English Abstract PMID: 17313001 [PubMed - in process] Zhou W, Wang LP, Zhang SY. | [Clinical application of acupoint sticking therapy] [Article in Chinese] | Zhongguo Zhen Jiu. 2006 Dec;26(12):899- 903. | Section of Acupuncture and Moxibustion, Huguosi Hospital Affiliated to Beijing Univ of TCM, Beijing 100035, China. dzhouwei | OBJECTIVE: To summarize clinical application of acupoint sticking therapy in various fields of Chinese medicine. METHODS: Review acupoint selection, drug selection and problems of clinical studies in acupoint sticking therapy. CONCLUSION: Acupoint sticking therapy has a good therapeutic effect with no adverse effect, safety and convenient manipulation. | Publication Types: English Abstract PMID: 17313017 [PubMed - in process] Zhou YL, Zhang SQ, Sun GS, Chen JH, Liu P, Liu YJ, Lin GP, Hu B. | [Clinical observation on ankle-three-needle for treatment of nerve root pain of prolapse of lumbar intervertebral disc] [Article in Chinese] | Zhongguo Zhen Jiu. 2006 Dec;26(12):847-50. | Section of Prolapse of Intervertebral Disc, The Third Affiliated Hospital of Henan College of Traditional Chinese Medicine, Zhengzhou 450008, China. youlong666 | OBJECTIVE: To observe the analgesic effect of ankle-three-needle on nerve root pain of prolapse of lumbar intervertebral disc. METHODS: Three hundred and eighty cases were randomly divided into an ankle-three-needle group, a routine AP group and a medication group. The ankle-three-needle group were treated with ankle-three-needle therapy, i. e. according to different prolapse segments, points Gentong No. 1, 2 and 3 were selected with lifting-kneading needle insertion method used and the needle was inserted along the skin; the routine AP group were treated with AP at Shenshu (BL23), Qihaishu (BL24) and Jiaji (EX-B 2) of the prolapse corresponding segment, and Ciliao (BL32), etc. with uniform reinforcing- reducing manipulation; the medication group were treated with routine buttock intramuscular injection of aspirin-DL-lysine plus saline. RESULTS: The time inducing analgesia was 6 min in the ankle-three-needle group, 27 min in the routine AP group and 18 min in the medication group. The effect- lasting time was 24.48 h in the ankle-three-needle group, 8.93 h in the routine AP group and 6.36 h in the medication group, with a significant difference as the ankle-three-needle group compared with both the routine AP group and the medication group, but with no significant difference between the routine AP group and the medication group. After treatment, there were very significant differences in change tendency of the analgesic score among the three groups at all the time points (P < 0.01). And there was very significant differences in the changing tendency of straight-leg raising test among the three groups at 0.5 h, 1 h, 24 h and 48 h (P < 0.001). CONCLUSION: Ankle-three-needle has obvious therapeutic effect on nerve root pain induced by prolapse of lumbar intervertebral disc. | Publication Types: English Abstract PMID: 17313003 [PubMed - in process] Best regards, Quote Link to comment Share on other sites More sharing options...
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