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Hep C and Interferon

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Hi Folks:

I just want to remind you all that HBV and HCV are very different animals.

The only thing in common is that they both cause hepatitis.

HBV cannot be cured or cleared with any medications or herbs--once in a while

seroconversion happens. Serocoversion may or may not be associated with viral

clearance.

HCV can be cleared (not always of course) with interferon treatment--especially

helped by

concomitant Chinese medicine therapy to help both with adherence and liver

health

HCV is a systemic disease that includes liver damage. HBV is primarily a liver

disease and

is much more quickly progressing to cirrhosis in people with elevated viral

load.

This is very different from HCV in which viral load makes no difference to

progression but

does make a difference in viral clearance.

Also, 95% people infected with HBV as adults become antibody positive but do not

develop

chronic liver disease. Very different from HCV where close to 80% become

chronic.

A very quick response as I am in the middle of writing a grant today--just want

wanted to

put my two cents in.

For those of you interested, we will be sponsoring another HCV Professional

Certification

Course in September.

Thanks,

Misha

, " "

wrote:

>

> I've uploaded the full Pine Street article to the Files Section folder

Hepatitis.

>

> It is about HBV, a slightly different animal. I have forgotten if I purchased

this document

> or was available free. Support Pine Street if it is a for-pay article.

> doug

>

>

>

>

> http://www.positivehealth.com/permit/Updates/rudherb3.htm

>

> Issue 85

> MCCULLOCH and colleagues, Pine Street Clinic, San Anselmo, CA, USA, analyze

> Chinese

> herbal medicine and interferon in the treatment of chronic hepatitis B.

> Background: This meta-analysis was performed in order to evaluate the

> effectiveness of

> Chinese herbal medicine alone or in combination with interferon-alpha in

> treating chronic

> hepatitis B.

>

> Methods: TCMLARS, AMED, CISCOM, EMBASE, MEDLINE,and Cochrane Collaboration

> databases were searched and the articles? bibliographies were handsearched.

>

> Results: Chinese herbal medicine significantly reduced sero-reversion of HbsAg

> and was

> equivalent to interferon-alpha in sero-reversion of HbeAg and Hepatitis B

virus

> DNA.

> Chinese herbal medicine combined with interferon-alpha significantly increased

> seor-

> reversion of HBsAg, HBeAg, and viral DNA.

>

> The Chinese herb active component bufotoxin combined with Interferon-alpha

> significantly increased HbeAg and viral DNA sero-reversion. The Chinese herb

> active

> component kurorinone was equivalent to interferon-alpha in sero-reversion of

> HbeAg and

> viral DNA.

>

> Conclusions: Although the quality of existing studies is poor, the data

> nevertheless

> suggest that further studies of Chinese herbal medicine and interferon in

> chronic hepatitis

> B infection are justified.

> McCulloch M, Broffman M, Gao J, Colford JMJr. Chinese herbal medicine and

> interferon in

> the treatment of chronic hepatitis B: a meta-analysis of randomized.

controlled

> trials.

> American Journal of Public Health 91 (10): 1619-1628, Oct 2002.

>

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Guest guest

Blue Poppy Herbs' Clear Heat Ointment

 

 

, " Sean Doherty " <sean

wrote:

>

> Does anyone have a good treatment for the swelling, itching, pain and

> redness that develops at the interferon injection sites?

>

>

>

> Thanks,

>

> Sean

>

>

>

>

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Guest guest

I have a new patient who told me he used to have HBV, and he got rid of it using

oxygen therapies. He claims to be free of all markers and traces for the

disease now.

 

 

 

Misha Cohen <TCMPaths wrote: Hi Folks:

I just want to remind you all that HBV and HCV are very different animals.

The only thing in common is that they both cause hepatitis.

HBV cannot be cured or cleared with any medications or herbs--once in a while

seroconversion happens. Serocoversion may or may not be associated with viral

clearance.

HCV can be cleared (not always of course) with interferon treatment--especially

helped by

concomitant Chinese medicine therapy to help both with adherence and liver

health

HCV is a systemic disease that includes liver damage. HBV is primarily a liver

disease and

is much more quickly progressing to cirrhosis in people with elevated viral

load.

This is very different from HCV in which viral load makes no difference to

progression but

does make a difference in viral clearance.

Also, 95% people infected with HBV as adults become antibody positive but do

not develop

chronic liver disease. Very different from HCV where close to 80% become

chronic.

A very quick response as I am in the middle of writing a grant today--just want

wanted to

put my two cents in.

For those of you interested, we will be sponsoring another HCV Professional

Certification

Course in September.

Thanks,

Misha

, " "

wrote:

>

> I've uploaded the full Pine Street article to the Files Section folder

Hepatitis.

>

> It is about HBV, a slightly different animal. I have forgotten if I

purchased this document

> or was available free. Support Pine Street if it is a for-pay article.

> doug

>

>

>

>

> http://www.positivehealth.com/permit/Updates/rudherb3.htm

>

> Issue 85

> MCCULLOCH and colleagues, Pine Street Clinic, San Anselmo, CA, USA, analyze

> Chinese

> herbal medicine and interferon in the treatment of chronic hepatitis B.

> Background: This meta-analysis was performed in order to evaluate the

> effectiveness of

> Chinese herbal medicine alone or in combination with interferon-alpha in

> treating chronic

> hepatitis B.

>

> Methods: TCMLARS, AMED, CISCOM, EMBASE, MEDLINE,and Cochrane Collaboration

> databases were searched and the articles? bibliographies were handsearched.

>

> Results: Chinese herbal medicine significantly reduced sero-reversion of

HbsAg

> and was

> equivalent to interferon-alpha in sero-reversion of HbeAg and Hepatitis B

virus

> DNA.

> Chinese herbal medicine combined with interferon-alpha significantly

increased

> seor-

> reversion of HBsAg, HBeAg, and viral DNA.

>

> The Chinese herb active component bufotoxin combined with Interferon-alpha

> significantly increased HbeAg and viral DNA sero-reversion. The Chinese herb

> active

> component kurorinone was equivalent to interferon-alpha in sero-reversion of

> HbeAg and

> viral DNA.

>

> Conclusions: Although the quality of existing studies is poor, the data

> nevertheless

> suggest that further studies of Chinese herbal medicine and interferon in

> chronic hepatitis

> B infection are justified.

> McCulloch M, Broffman M, Gao J, Colford JMJr. Chinese herbal medicine and

> interferon in

> the treatment of chronic hepatitis B: a meta-analysis of randomized.

controlled

> trials.

> American Journal of Public Health 91 (10): 1619-1628, Oct 2002.

>

 

 

 

 

 

 

 

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Guest guest

> , " G Hudson " <crudo20@> wrote:

> >

> > I don't want to hijack the thread here... but would this interaction

> > with interferon also apply to MS patients getting interferon?

> >

> > Geoff

 

I can see MS and interferon having the exact same issues.

 

To pick up on some of Misha's comments, the hospital I observed in didn't use

Chai Hu as

they thought it was too damaging to the liver. If I can say that they had a

subsititute I

would say they were big on Mei Gui Hua, and I've learned to appreciate it as

well.

The one thing I can say about Chai Hu, is if it does increase interferon levels

then why not use it when safe to help fight the virus? After all, one of my

patients may be

going on a super low dose of interferon. Still I haven't put Chai Hu in my

" patent " formula

that I had made up in

bulk.

 

doug

> >

>

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