Guest guest Posted June 4, 2007 Report Share Posted June 4, 2007 Hi All, Koo ST, Lim KS, Chung K, Ju H, Chung JM. Electroacupuncture-induced analgesia in a rat model of ankle sprain pain is mediated by spinal alpha- adrenoceptors. Pain. 2007 May 28; [Epub ahead of print]. Department of Medical Research, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea. In a previous study, we showed that electroacupuncture (EA) applied to acupoint SI06 on the contralateral forelimb produces long-lasting and powerful analgesia in pain caused by ankle sprain in a rat model. To investigate the underlying mechanism of EA analgesia, the present study tested the effects of various antagonists on known endogenous analgesic systems in this model. Ankle sprain was induced in anesthetized rats by overextending their right ankle with repeated forceful plantar flexion and inversion of the foot. When rats developed pain behaviors (a reduction in weight-bearing of the affected hind limb), EA was applied to acupoint SI06 on the contralateral forelimb for 30min under halothane anesthesia. EA significantly improved the weight-bearing capacity of the affected hind limb for 2h, suggesting an analgesic effect. The alpha-adrenoceptor antagonist phentolamine (2mg/kg, i.p. or 30mug, i.t.) completely blocked the EA- induced analgesia, whereas naloxone (1mg/kg, i.p.) failed to block the effect. These results suggest that EA-induced analgesia is mediated by alpha-adrenoceptor mechanisms. Further experiments showed that intrathecal administration of yohimbine, an alpha(2)-adrenergic antagonist, reduced the EA-induced analgesia in a dose-dependent manner, whereas terazosin, an alpha(1)-adrenergic antagonist, did not produce any effect. These data suggest that the analgesic effect of EA in ankle sprain pain is, at least in part, mediated by spinal alpha(2)-adrenoceptor mechanisms. PMID: 17537577 [PubMed - as supplied by publisher] Pearson S, Colbert AP, McNames J, Baumgartner M, Hammerschlag R. Electrical skin impedance at acupuncture points. J Altern Complement Med. 2007 May;13(4):409-18. Biomedical Signal Processing Laboratory, Portland State University, Portland, OR. Objectives: To test whether electrical skin impedance at each of three acupuncture points (APs) is significantly lower than at nearby sites on the meridian (MP) and off the meridian (NP). Design: Two instruments-Prognos (MedPrevent GmbH, Waldershof, Germany), a constant-current (DC) device, and PT Probe (designed for this study), a 100- Hz sinusoidal-current (AC) device-were used to record electrical impedance at three APs (right Gallbladder 14, right Pericardium 8, and left Triple Energizer 1), and two control sites for each AP. Each AP, MP, and NP was measured four times in random order with each device. Setting: The study was conducted over a period of 4 days at the Oregon College of Oriental Medicine (OCOM). Subjects: Twenty (20) healthy adults (14 women and 6 men), all recruited from the OCOM student body and faculty, participated in the study. Results: The Prognos measurements had an intraclass correlation (ICC) = 0.84 and coefficient of variation (CV) = 0.43. The PT Probe had ICC = 0.81 and CV = 0.31. Impedance values at APs were not significantly less than at MPs or NPs. Impedance values at MPs were also not significantly less than NPs, although their individual p values were <0.05 in 4 of 6 cases. There was a significant trend of increasing impedance with repeated measurements with both the Prognos (p =0.003) and the PT Probe (p= 0.003). Conclusions: Within the reliability limits of our study methods, none of the three APs tested has lower skin impedance than at either of the nearby control points. These results are not consistent with previous studies that detected lower skin impedance at APs than nearby sites. Further study is necessary to determine whether MPs have lower skin impedance than nearby NPs. Our study suggests caution is warranted when developing, using, and interpreting results from electrodermal screening devices. Further studies are needed to clarify the clinically important and controversial hypothesis that APs are sites of lower impedance. PMID: 17532733 [PubMed - in process] Sch¨¹ller BK, Neugebauer EA. [Evidence for laser acupuncture in cases of orthopedic diseases : A systematic review.][Article in German]. Schmerz. 2007 May 26; [Epub ahead of print]. Institut f¨¹r Forschung in der operativen Medizin (IFOM), Fakult0S0t f¨¹r Medizin der Universit0S0t Witten/Herdecke, Ostmerheimer Str. 200, 51109, K0<1ln, Deutschland, sekretariat-neugebauer BACKGROUND AND OBJECTIVES: The aim of this review is to evaluate the evidence for laser acupuncture in selected orthopaedic diseases. MATERIAL AND METHODS: Randomized controlled studies, meta-analyses and systematic reviews were identified by a systematic search strategy in Medline and the Cochrane library. The studies were evaluated using the quality criteria of the Oxford Centre of Evidence Based Medicine. RESULTS: For the selected orthopedic diseases (medial and lateral epicondylitis, myofascial pain syndrome of the neck, back and shoulder and osteoarthritis), meta-analyses, systematic reviews and eight randomized controlled studies were found. All other published studies used laser therapy without consideration of classical acupuncture points. All studies had significant drawbacks in methodological quality and the number of patients included. In more recent trials, improvement towards higher methodological quality was obvious. Although current evidence is equivocal, positive effects can be assumed in myofascial pain syndromes of the neck, back and shoulder. Laser acupuncture is advantageous in terms of side effects compared to classical acupuncture techniques. CONCLUSION: Better, well designed randomized studies with higher power are mandatory in orthopedic diseases. PMID: 17530300 [PubMed - as supplied by publisher] Shi HF, Zheng XH. [Effect of scalp acupuncture drawing method on motor function in hemiplegic patients following cerebral thrombosis at convalescent period][Article in Chinese]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007 Apr;27(4):361-3. Dept of Rehabilitation, The First Affiliated Hospital of Medical College of Zheijiang University, Hangzhou. OBJECTIVE: To observe the effect of scalp-acupuncture drawing method (SADM) on recovering motor function in hemiplegic patients following cerebral thrombosis at convalescent period. METHODS: Adopting randomized, single-blinded, controlled method, 93 hemiplegic patients following cerebral thrombosis were randomly assigned to 3 groups, 31 in each group. All patients received routine neurological therapy but those in the treated group (SADM) and the control group I (SATM) also received SADM and scalp- acupuncture twirling method (SATM), respectively; those in control group II received no additional treatment. The treatment course for all was 4 weeks. RESULTS: Before treatment, there were insignificant difference among 3 groups in the score of neural motor function deficits (NFDS) of limbs and activity of daily life (ADL) score (P>.05). After being treated for 4 weeks, the NFDS was significantly lower in control group II (P<.01, P<.05) and the change of the scores in the treated group was more than that in the control group I (P < 0.05). CONCLUSION: SADM was superior to SATM to improve the ADL score and motor function of hemiplegia patients following cerebral thrombosis in the convalescent stage. PMID: 17526181 [PubMed - in process] Xie S, Liang J, Yan CY. [Therapeutic effects of acupoint drug-finger pressing on gastroesophageal reflux][Article in Chinese]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007 Apr;27(4):355-8. Dept of Gastroenterology, Liuzhou Hospital of Traditional , Guangxi. xsh6566 OBJECTIVE: To observe the clinical effects and possible mechanism of acupoint drug-finger pressing (ADFP) on gastroesophageal reflux (GER). METHODS: 80 patients were randomly assigned to the treatment group and the control group, 40 in each group. The treatment group was treated by ADFP on Ganshu (BL18), Danshu (BL19), Weishu (BL21) and Pishu (BL20) acupoint bilaterally with pressing and kneading maneuver for 15 min each time, twice per day; the control group was treated with acid-inhibitory and gastrokinetic drugs as omeprazole enteric-coated tablets (20mg at a 12-h interval) and cisapride tablets (10 mg, thrice daily, taken 15 min before meals). The treatment course for both was 3 weeks. RESULTS: The symptom score and esophageal pressure obviously decreased (P<.05), esophageal pressure was relieved remarkably (P<.05) in both groups after treatment with insignificant difference between the groups (P>.05). The ratio of 24-h esophageal reflux times and total reflux time, the times of reflux lasting for more than 5 min and the maximum reflux time were all lowered obviously in all patients after treatment, and the improvements was significantly different between the two groups (P<.05). Upper gastrointestinal endoscopy suggested obvious amelioration in esophagitis. The total effective rate was 97.5% in the treatment group, significantly higher than that in the control group (80.0%) (P<.05). No obvious adverse reaction was found. CONCLUSION: Based on TCM, ADFP therapy is a new approach to treat GER with prominent effects and less adverse reaction, and is easily be accepted by patients. ADFP therapy deserves general use in payients with GER. PMID: 17526179 [PubMed - in process] Zhao HL, Gao X, Gao YB. [Clinical observation on effect of acupuncture in treating diabetic peripheral neuropathy][Article in Chinese]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007 Apr;27(4):312-4. Acupuncture and Massage College of Beijing University of , Beijing. dfyynfm OBJECTIVE: To observe the effect of acupuncture in treating diabetic peripheral neuropathy (DPN). METHODS: 60 patients with DPN were randomly assigned to an acupuncture treated group and a control group, 30 in each group. Besides basic treatment, patients were treated additionally with acupuncture and oral administration of Methycobal (Mecolbalamin) for 8 weeks respectively. Changes of symptoms, blood glucose, HbA1c, whole blood and plasma viscosity, the nerve conduction velocity (NCV) of sensory and motor nerves before and after treatment were observed. RESULTS: Acupuncture ameliorated nervous system symptoms and signs, decreased whole blood and plasma viscosity, and improved the NCV of sensory and motor nerves in patients with DPN. CONCLUSION: Acupuncture had a definite effect of in treating DPN. PMID: 17526168 [PubMed - in process] Liu JP, Xia Y. [Quality appraisal of systematic reviews or meta-analysis on traditional Chinese medicine published in Chinese journals][Article in Chinese]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007 Apr;27(4):306-11. Beijing University of , Beijing. jianping-l OBJECTIVE: To critically assess the quality of literature about systematic review or meta-analysis on traditional Chinese medicine (TCM) published in Chinese journals. METHODS: Electronic searches in CNKI, VIP and Wanfang data-base were conducted to retrieve the systematic reviews or meta-analysis reports on TCM, including herbal medicine, needling, acupuncture and moxibustion, as well as integrative medicine, they were identified and extracted according to the 18 items of QUOROM (quality of reporting of meta-analyses) Statement and relative information. The appraisal was made taking the indexes mainly including objectives, source of data, methods of data extraction, quality assessment of the included studies, measurement data synthesis, etc. RESULTS: Eighty-two systematic reviews were identified, except 6 reviews were excluded for repeatedly published or didn't comply with the enrolled criterion, 76 reviews concerning 51 kinds of diseases were enrolled for appraisal. Among them, 70 reviews evaluated the efficacy of TCM, mainly on Chinese herbs and 9 on acupuncture and moxibustion. In majority of the reviews, randomised controlled trials were included and the data resources were described, but in 26 reviews only the Chinese databases were searched and the description about data extraction and analysis method were too simple; and 70% of reviews assessed the quality of the included studies; none used flow chart to express the process of selection, inclusion and exclusion of studies. CONCLUSIONS: Few reviews or Meta-analysis reports reached the international standard and there is insufficient description of methodology for conducting systematic reviews, so it is hardly to be repeated. The authors suggested that advanced methodological training is necessary for reviewers. PMID: 17526167 [PubMed - in process] Best regards, Quote Link to comment Share on other sites More sharing options...
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