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I'm looking for recommendations on an encapsulation machine. I'm

familiar with the ones that sell for around 20 - 50 dollars, but they

take as long as 15 - 20 minutes to make 100 capsules. I'd like to find

something more efficient, but not a large industrial-scale machine.

Any ideas?

 

- Bill Schoenbart

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On 9/28/07, bill_schoenbart <plantmed2 wrote:

>

> I'm looking for recommendations on an encapsulation machine. I'm

> familiar with the ones that sell for around 20 - 50 dollars, but they

> take as long as 15 - 20 minutes to make 100 capsules. I'd like to find

> something more efficient, but not a large industrial-scale machine.

> Any ideas?

>

> - Bill Schoenbart

>

 

 

 

 

 

 

 

 

 

The next level up from the plastic 20-50 dollar jobs is the $350-400 job.

 

It makes 100 capsules in 5-7 minutes. Still requires you to stand there, but

if you make a lot of capsules, this will pay for itself really quick. I

wouldn't trade mine in for all the tea in... well, you know. ;)

 

-al.

 

 

--

, DAOM

Pain is inevitable, suffering is optional.

 

 

 

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Hi Al, any brand names or url to visit?

 

Thanks,

 

Fernando

 

 

, " Al Stone " <al wrote:

>

> On 9/28/07, bill_schoenbart <plantmed2 wrote:

> >

> > I'm looking for recommendations on an encapsulation machine. I'm

> > familiar with the ones that sell for around 20 - 50 dollars, but they

> > take as long as 15 - 20 minutes to make 100 capsules. I'd like to find

> > something more efficient, but not a large industrial-scale machine.

> > Any ideas?

> >

> > - Bill Schoenbart

> >

>

>

>

The next level up from the plastic 20-50 dollar jobs is the $350-400

job.

>

> It makes 100 capsules in 5-7 minutes. Still requires you to stand

there, but

> if you make a lot of capsules, this will pay for itself really quick. I

> wouldn't trade mine in for all the tea in... well, you know. ;)

>

> -al.

>

>

> --

> , DAOM

> Pain is inevitable, suffering is optional.

>

>

>

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I don't see any brand name on my unit. All those that I've seen in the OM

medical suppliers is the same unit, made predominately out of high-impact

plastic. I might add too that I chipped off a corner of the unit once and

superglued it back on. It hasn't caused any problems.

 

This is the unit that I have. I might have purchased it here too, but I

can't remember, nor do I have any interest in sales from this or any capsule

filling manufacturer or distributor:

*http://tinyurl.com/ypofam*

 

This one looks similar, it appears that the tray into which one would pour

the extract powder is larger, which prevents spillage.

*http://tinyurl.com/2xubvn*

 

Now, there is a model/brand that is a step up in quality, size options, and

cost. This is marketed to compounding pharmacies and researchers in

pharmacology. I just can't locate it after 25 minutes at Google. It is made

of stainless steel and comes in 100 and 200 capsule sizes. As I recall, it

retailed in the $700 range. It is roughly the same as the models above, but

presumably can go into a dishwasher. It also had some design features that

also prevent spillage of the extract powders.

 

 

On 9/29/07, fbernall <fbernall wrote:

>

> Hi Al, any brand names or url to visit?

>

> Thanks,

>

> Fernando

>

> --- In

<%40>,

> " Al Stone " <al wrote:

>

> >

> > On 9/28/07, bill_schoenbart <plantmed2 wrote:

> > >

> > > I'm looking for recommendations on an encapsulation machine. I'm

> > > familiar with the ones that sell for around 20 - 50 dollars, but they

> > > take as long as 15 - 20 minutes to make 100 capsules. I'd like to find

> > > something more efficient, but not a large industrial-scale machine.

> > > Any ideas?

> > >

> > > - Bill Schoenbart

>

 

 

--

, DAOM

Pain is inevitable, suffering is optional.

 

 

 

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, " Al Stone " <al wrote:

Thanks, Al.

 

I've been looking at this one by ProFill.

 

What is the general consensus regarding the use of gelatin or

vegetarian capsules?

 

Thanks,

 

Fernando

 

 

>

> This one looks similar, it appears that the tray into which one

would pour

> the extract powder is larger, which prevents spillage.

> *http://tinyurl.com/2xubvn*

>

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, " fbernall " <fbernall

wrote:

>

> , " Al Stone " <al@> wrote:

Fernando,

 

Can you provide a link?

 

- Bill

 

 

> Thanks, Al.

>

> I've been looking at this one by ProFill.

>

> What is the general consensus regarding the use of gelatin or

> vegetarian capsules?

>

> Thanks,

>

> Fernando

>

>

> >

> > This one looks similar, it appears that the tray into which one

> would pour

> > the extract powder is larger, which prevents spillage.

> > *http://tinyurl.com/2xubvn*

> >

>

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Al,

 

Which suppliers carry that one that makes 100 capsules in 5-7

minutes?

 

I have found a really nice one, but it costs over 800 dollars. It

has an online video that shows how to use it:

 

http://capsuleconnection.com/index.php?

option=com_content & task=view & id=22 & Itemid=40

 

- Bill

 

 

>

The next level up from the plastic 20-50 dollar jobs is the $350-

400 job.

>

> It makes 100 capsules in 5-7 minutes. Still requires you to stand

there, but

> if you make a lot of capsules, this will pay for itself really

quick. I

> wouldn't trade mine in for all the tea in... well, you know. ;)

>

> -al.

>

>

> --

> , DAOM

> Pain is inevitable, suffering is optional.

>

>

>

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I offer the vegie caps when they're requested. They're a tad more expensive

than the gelatin capsules, but that doesn't effect my choice, its really

about the patient's preferences. Mostly, I'll offer the vegie caps for

religious types who observe kosher laws or something like that. Or, if

they're vegan or otherwise leaning in that direction and don't want animal

stuff in their capsules.

 

The gel caps are easier to work with. They're slicker and move in and out of

the capsule filling apparatus more easily. They're more sturdy too and so

when you compress together the flat of caps, they're less likely to buckle

in on the ends. That end buckling shouldn't have any effect on clinical

efficacy, but it could be more uncomfortable to swallow and of course it

looks a little amateurish which I like to avoid.

 

Another question is the use of colored capsules. I use a few different color

combos for my formulas. There's a company that advertises in Acupuncture

Today that charges something like $18 per 1,000 capsules. I myself get mine

from India for $8.50 per 1,000. However I order 20,000 at a time and making

the purchase is a huge hassle that includes a Western Union transfer and

lots of waiting time while the office workers over there are away at a

wedding or can't get to work due to flooding or whatever other problems slow

down the process. That being said, if you can anticipate it taking about a

month to get the capsules, it isn't a problem, just gotta plan ahead.

 

This Indian company also includes some sort of " bacteria and virus free "

declaration. I'm not 100% sure I can vouch for the cleanliness of the

capsules, which is one of my concerns, but by the same token, how many of us

really ask that question of any of our capsule suppliers? How do the caps

get from the manufacturer and into that plastic bag full of 1,000 pieces.

Who knows who's hands or factories those capsules have passed through?

 

Incidentally, the instructions on those better manual capsule filling

machines can be spotty coming from the manufacturer. Here's something I

found this morning that may help:

http://www.capsuleworld.com/profill_quick_start_guide.htm

 

And here are some other fillers and the materials from which they're made

(useful information if you want to know how to clean your machine):

http://www.capsuleworld.com/materials_used.htm

 

-al.

 

On 9/29/07, fbernall < fbernall wrote:

>

> --- In

<%40>,

> " Al Stone " <al wrote:

> Thanks, Al.

>

> I've been looking at this one by ProFill.

>

> What is the general consensus regarding the use of gelatin or

> vegetarian capsules?

>

> Thanks,

>

> Fernando

>

> >

> > This one looks similar, it appears that the tray into which one

> would pour

> > the extract powder is larger, which prevents spillage.

> > *http://tinyurl.com/2xubvn*

> >

>

>

>

 

 

 

--

, DAOM

Pain is inevitable, suffering is optional.

 

 

 

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Gracias Caballo! Ya' Da' Man!

 

Fernando

 

, " Al Stone " <al wrote:

>

> I offer the vegie caps when they're requested. They're a tad more

expensive

> than the gelatin capsules, but that doesn't effect my choice, its really

> about the patient's preferences. Mostly, I'll offer the vegie caps for

> religious types who observe kosher laws or something like that. Or, if

> they're vegan or otherwise leaning in that direction and don't want

animal

> stuff in their capsules.

 

> --

> , DAOM

> Pain is inevitable, suffering is optional.

>

>

>

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Thanks Fernando. That's the same one I linked to in a previous email.

It looks really nice, but it's over 800 dollars. It might still be

worth it, considering all the time it should save.

 

- Bill

 

 

> > Fernando,

> >

> > Can you provide a link?

>

> Bill, try this one..

>

> *http://tinyurl.com/2xubvn*

>

> Fernando

>

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There's also a $1,500 machine that is suppose to separate the

male/female sides and cap them after filling. There's an ad in

acupuncturetoday for it and they have a video you can buy. If you

want, contact me off list and I can send it to you if you can't find it.

 

Geoff

 

 

, " bill_schoenbart "

<plantmed2 wrote:

>

> I'm looking for recommendations on an encapsulation machine. I'm

> familiar with the ones that sell for around 20 - 50 dollars, but they

> take as long as 15 - 20 minutes to make 100 capsules. I'd like to find

> something more efficient, but not a large industrial-scale machine.

> Any ideas?

>

> - Bill Schoenbart

>

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I went ahead and ordered the Profill machine. At 900 dollars with

shipping, I'm hoping it lives up to the hype!

 

- Bill

 

 

 

, " G Hudson " <crudo20

wrote:

>

> There's also a $1,500 machine that is suppose to separate the

> male/female sides and cap them after filling. There's an ad in

> acupuncturetoday for it and they have a video you can buy. If you

> want, contact me off list and I can send it to you if you can't

find it.

>

> Geoff

>

>

> , " bill_schoenbart "

> <plantmed2@> wrote:

> >

> > I'm looking for recommendations on an encapsulation machine. I'm

> > familiar with the ones that sell for around 20 - 50 dollars, but

they

> > take as long as 15 - 20 minutes to make 100 capsules. I'd like

to find

> > something more efficient, but not a large industrial-scale

machine.

> > Any ideas?

> >

> > - Bill Schoenbart

> >

>

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Bill - I'd be interested in a first-hand review of how that one works for

you...

 

On a similar note - what size capsules are you (all) using? Presumming you

are using granules, how many capsules does it take (of what size) to get to

the 10+g/day dosing?

 

J

 

 

On 10/1/07, bill_schoenbart <plantmed2 wrote:

>

> I went ahead and ordered the Profill machine. At 900 dollars with

> shipping, I'm hoping it lives up to the hype!

>

> - Bill

>

> .

>

 

 

 

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On 10/7/07, Joy Keller <JKellerLAc wrote:

>

> On a similar note - what size capsules are you (all) using? Presumming

> you

> are using granules, how many capsules does it take (of what size) to get

> to

> the 10+g/day dosing?

>

 

 

 

 

 

The industry standard for capsule size is the 500mg Size " 0 " capsules.

 

As for how much is actually in a capsule, it kind of depends on the extract

product you're using.

 

Just based on my personal experience with the different powders, I'd say

that to make 100 capsules, it takes the following quantities:

 

Evergreen, KPC, and Taiwanese ( " GMP " ) extracts: 45g

Bluelight (Tianjiang), E-Fong: 55g

Brion: 35g.

 

Brion is the finest, most airy powders of them all. Really difficult to work

with in my opinion. They require tamping down multiple times to fit the

extract into the capsules, while the heavier brands from mainland China

don't require tamping, because they pretty well fill up the capsule tightly

when poured in.

 

So, based on the qualities of the herb extract, the quantity within each

capsule will be different. 100 caps containing 50g of extract powder means

that each capsule gets .5 grams (or 500 milligrams). So, if you're getting

500 mg into each capsule, then it'll take 20 capsules to meet your 10g dose.

 

Problem is, its really difficult to get any kind of compliance for 60

capsules per day. So I start with 5x3 for capsules, or double that amount of

straight powders which I prefer nowadays. The powders are cheaper because

they don't require my extra labor and a little bit of cost for capsules, but

also the patient can handle a larger dosage psychologically, and to a

certain extent in their tummies as that number of capsules is uncomfortable

for some.

 

Exceptions are the really icky heat clearing herbs like long dan cao and the

bitter " huang " herbs. Those I'll sometimes encourage that people use the

capsules.

 

As for efficacy, there's little doubt in my mind that the powders are much

more potent. Our body's respond immediately to the taste, while in capsules,

we have to wait for digestion to take place.

 

Favoring the powders also serves to kind of stimulate a placebo too. The

worst the taste, the more that psyche thinks that it must work well. ;) I

like to use the powders also because I favor committed patients over

looky-loos. That's perhaps not the best business choice, but I would much

rather fret over serious patients than those looking to be cool or whatever

their motivations may be.

 

-al.

 

--

, DAOM

Pain is inevitable, suffering is optional.

 

 

 

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> The Profill capsule system/²machine² works very well for encapsulating Custom

> Prescriptions.

> Crane Herb Pharmacy and Crane-West Herb Pharmacy each uses 4 ³machines².

> Cleaning all the parts between prescriptions takes over 15 minutes and the

> drying time can be reduced using 70% alcohol.

> SOPs(Standard Operating Procedures) within GMPs require decontaminating the

> machine between batches.

> Liability Insurance requires compliance with GMPs.

>

> Size ³0² Vegi capsules hold between 285 and 445 mg of KPC ³powder² per capsule

> with proper tamping.

> (Average KPC ³powder² weight is 330-335 mg per ³0² cap).

> So, for a 3 gm/dose prescription, the label will show a dosage between 7 and

> 11 caps per dose.

> To calculate the weight of powder in a cap :

> 1. Weigh the entire bottle (scale accurate to .001).

> 2. Deduct [#caps X 93mg(example weight of empty vegi cap shell varies between

> 92 and 97mg).

> 3. Deduct weight of empty plastic container.

> 4. Divide NET weight by #caps in bottle.

 

When #caps will not fit in 1 bottle, the weight of same formula

powder will differ between 3-7mg for 2 bottles due to variations in

tamping powder into caps.

 

Another big herb powder issue is the blending of various singles and

formulas (with different weights and densities) into a

homogeneous prescription. Crane uses a Turbula : from Switzerland,

it is used in the lab by the pharmaceutical industry (and the

cosmetics, explosives and other industries to accurately blend

ingredients that vary in weight and density). After 15 minutes of

blending, each dose has the same ingredient% that the practitioner

defined in their patient¹s formula.

 

We have also identified 6 ³clumpy² herbs that need special

attention.

Zirconium marbles are put into a bottle to break down the clumps.

Zirconium marbles do not chip when they collide in a bottle; unlike,

stainless steel marbles.

 

Sampling continues to be a major concern for the FDA in their

oversight of minute active pharmaceutical ingredients blended with

large amounts of binder and filler : each tablet or capsule is

supposed to have the same #mg of active ingredient in each tab/cap.

 

The above issues are relevant to accurate manufacturing of Custom

Prescriptions within the guidelines of the new FDA GMPs.

 

In my opinion, the OM community needs to realize that the current

³appropriate training² of practitioners mixing herb

prescriptions (for their own patient) will be seen as grossly

inadequate by the FDA.

Schools (and CEU programs) will need to develop and teach

³Compounding and GMP Protocol² that will provide reasonable safety

concerns for the FDA. I believe that the NCCAOM should adequately

test practitioners on their knowledge of this protocol.

This protocol does not have to be expensive but practitioners will

need to be diligent in following these low-tech SOPs

(Standard Operating Procedures).

 

Technically, schools, who have more than 20 employees. have to

comply with the new GMPs in less than 2 years;

practitioners in less than 3 years.

 

What will be the appropriate Forum for concerned practitioners and

schools to come together and define these Protocols

for raw herb and concentrated ³powder² Custom Prescription

compounding? I presume this Forum will need to organized by the

AAAOM, CAOMA and NCCAOM.

 

Let¹s define these Protocols before the FDA sets standards that will

not be appropriate or financially reasonable.

 

 

Bill Egloff

Crane Herb Co.

Crane Herb Pharmacy

Crane-West Herb Pharmacy

Chinese Herb Product Committee of AHPA ­ Co-Chair

 

 

 

 

 

>

>

>

> Al Stone :

>

> The industry standard for capsule size is the 500mg Size " 0 " capsules.

>

> As for how much is actually in a capsule, it kind of depends on the extract

> product you're using.

>

> Just based on my personal experience with the different powders, I'd say

> that to make 100 capsules, it takes the following quantities:

>

> Evergreen, KPC, and Taiwanese ( " GMP " ) extracts: 45g

> Bluelight (Tianjiang), E-Fong: 55g

> Brion: 35g.

>

> Brion is the finest, most airy powders of them all. Really difficult to work

> with in my opinion. They require tamping down multiple times to fit the

> extract into the capsules, while the heavier brands from mainland China

> don't require tamping, because they pretty well fill up the capsule tightly

> when poured in.

>

> So, based on the qualities of the herb extract, the quantity within each

> capsule will be different. 100 caps containing 50g of extract powder means

> that each capsule gets .5 grams (or 500 milligrams). So, if you're getting

> 500 mg into each capsule, then it'll take 20 capsules to meet your 10g dose.

>

> Problem is, its really difficult to get any kind of compliance for 60

> capsules per day. So I start with 5x3 for capsules, or double that amount of

> straight powders which I prefer nowadays. The powders are cheaper because

> they don't require my extra labor and a little bit of cost for capsules, but

> also the patient can handle a larger dosage psychologically, and to a

> certain extent in their tummies as that number of capsules is uncomfortable

> for some.

>

> Exceptions are the really icky heat clearing herbs like long dan cao and the

> bitter " huang " herbs. Those I'll sometimes encourage that people use the

> capsules.

>

> As for efficacy, there's little doubt in my mind that the powders are much

> more potent. Our body's respond immediately to the taste, while in capsules,

> we have to wait for digestion to take place.

>

> Favoring the powders also serves to kind of stimulate a placebo too. The

> worst the taste, the more that psyche thinks that it must work well. ;) I

> like to use the powders also because I favor committed patients over

> looky-loos. That's perhaps not the best business choice, but I would much

> rather fret over serious patients than those looking to be cool or whatever

> their motivations may be.

>

> -al.

 

 

 

 

 

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