Guest guest Posted October 26, 2007 Report Share Posted October 26, 2007 Does anyone know what the ingredients of this formula are? Zai Zao San maybe? Thanks, Sean The Chinese herbal medicine formula FAHF-2 completely blocks anaphylactic reactions in a murine model of peanut allergy. Srivastava KD,Kattan JD,Zou ZM,Li JH, Zhang L, Wallenstein S,Goldfarb J,Sampson HA,Li XM. Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 10029-6574, USA. BACKGROUND: Peanut allergy is potentially life threatening. There is no curative therapy for this disorder. We previously found that an herbal formula, food allergy herbal formula (FAHF)-1, blocked peanut-induced anaphylaxis in a murine model when challenged immediately posttherapy. OBJECTIVE: To test whether FAHF-2, an improved herbal formula, from which 2 herbs, Zhi Fu Zi (Radix Lateralis Aconiti Carmichaeli Praeparata) and Xi Xin (Herba Asari), were eliminated, is equally effective to FAHF-1, and if so, whether protection persists after therapy is discontinued. METHODS: Mice allergic to peanut treated with FAHF-2 for 7 weeks were challenged 1, 3, or 5 weeks posttherapy. Anaphylactic scores, core body temperatures, vascular leakage, and plasma histamine levels after peanut challenge were determined. Serum peanut-specific antibody levels and splenocyte cytokine profiles were also measured. RESULTS: After challenges, all sham-treated mice developed severe anaphylactic signs, significant decrease in rectal temperatures, significantly increased plasma histamine levels, and marked vascular leakage. In contrast, no sign of anaphylactic reactions, decrease in rectal temperatures, or elevation of plasma histamine levels was observed in FAHF-2-treated mice in 5 separate experiments. IgE levels were significantly reduced by FAHF-2 treatment and remained significantly lower as long as 5 weeks posttherapy. Splenocytes from FAHF-2-treated mice showed significantly reduced IL-4, IL-5, and IL-13, and enhanced IFN-gamma production to recall peanut stimulation in vitro . CONCLUSION: FAHF-2 treatment completely eliminated anaphylaxis in mice allergic to peanut challenged as long as 5 weeks posttherapy. This result was associated with downregulation of T H 2 responses. FAHF-2 may be a potentially effective and safe therapy for peanut allergy. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 27, 2007 Report Share Posted October 27, 2007 Hi Sean, It will be interesting to see if that info is available. I believe they are working on a patent for this formula. Cheers, Michael - Sean Doherty Friday, October 26, 2007 3:50 PM Allergy Formula Does anyone know what the ingredients of this formula are? Zai Zao San maybe? Thanks, Sean The Chinese herbal medicine formula FAHF-2 completely blocks anaphylactic reactions in a murine model of peanut allergy. Srivastava KD,Kattan JD,Zou ZM,Li JH, Zhang L, Wallenstein S,Goldfarb J,Sampson HA,Li XM. Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 10029-6574, USA. BACKGROUND: Peanut allergy is potentially life threatening. There is no curative therapy for this disorder. We previously found that an herbal formula, food allergy herbal formula (FAHF)-1, blocked peanut-induced anaphylaxis in a murine model when challenged immediately posttherapy. OBJECTIVE: To test whether FAHF-2, an improved herbal formula, from which 2 herbs, Zhi Fu Zi (Radix Lateralis Aconiti Carmichaeli Praeparata) and Xi Xin (Herba Asari), were eliminated, is equally effective to FAHF-1, and if so, whether protection persists after therapy is discontinued. METHODS: Mice allergic to peanut treated with FAHF-2 for 7 weeks were challenged 1, 3, or 5 weeks posttherapy. Anaphylactic scores, core body temperatures, vascular leakage, and plasma histamine levels after peanut challenge were determined. Serum peanut-specific antibody levels and splenocyte cytokine profiles were also measured. RESULTS: After challenges, all sham-treated mice developed severe anaphylactic signs, significant decrease in rectal temperatures, significantly increased plasma histamine levels, and marked vascular leakage. In contrast, no sign of anaphylactic reactions, decrease in rectal temperatures, or elevation of plasma histamine levels was observed in FAHF-2-treated mice in 5 separate experiments. IgE levels were significantly reduced by FAHF-2 treatment and remained significantly lower as long as 5 weeks posttherapy. Splenocytes from FAHF-2-treated mice showed significantly reduced IL-4, IL-5, and IL-13, and enhanced IFN-gamma production to recall peanut stimulation in vitro . CONCLUSION: FAHF-2 treatment completely eliminated anaphylaxis in mice allergic to peanut challenged as long as 5 weeks posttherapy. This result was associated with downregulation of T H 2 responses. FAHF-2 may be a potentially effective and safe therapy for peanut allergy. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 29, 2007 Report Share Posted October 29, 2007 This formula is as follows: ling zhi (ganoderma lucidum), 28.17% wu mei (fructus pruni mume), 28.17% huang lian (rhizoma coptidis), 8.46% ren shen (radix ginseng), 8.45% huang bai (cortex phellodendri), 5.63% gan jiang (rhizoma zingiberis officinalis), 8.45% dang gui (radix angelicae sinensis), 8.45% gui zhi (ramulus cinnamomi cassiae), 2.81% chuan jiao (pericarpium zanthoxyli bungeanum), 1.41% You can read about it at the end of the following article. http://www.acupuncturetoday.com/mpacms/at/article.php?id=30254 David Russell, L.Ac., CMT Russell Family Acupuncture 134 Howard Street Petaluma, CA 94952 707.773.3375 www.acuherbal.com On Oct 27, 2007, at 6:22 AM, Nashua Acupuncture wrote: > Hi Sean, > > It will be interesting to see if that info is available. I believe > they are working on a patent for this formula. > > Cheers, > Michael > > - > Sean Doherty > > Friday, October 26, 2007 3:50 PM > Allergy Formula > > Does anyone know what the ingredients of this formula are? Zai Zao San > maybe? > > Thanks, > > Sean > > The Chinese herbal medicine formula FAHF-2 completely blocks > anaphylactic > reactions in a murine model of peanut allergy. > Srivastava KD,Kattan JD,Zou ZM,Li JH, Zhang L, Wallenstein S,Goldfarb > J,Sampson HA,Li XM. > Department of Pediatrics, Mount Sinai School of Medicine, New York, NY > 10029-6574, USA. > > BACKGROUND: Peanut allergy is potentially life threatening. There > is no > curative therapy for this disorder. We previously found that an herbal > formula, food allergy herbal formula (FAHF)-1, blocked peanut-induced > anaphylaxis in a murine model when challenged immediately posttherapy. > OBJECTIVE: To test whether FAHF-2, an improved herbal formula, from > which 2 > herbs, Zhi Fu Zi (Radix Lateralis Aconiti Carmichaeli Praeparata) > and Xi Xin > (Herba Asari), were eliminated, is equally effective to FAHF-1, and > if so, > whether protection persists after therapy is discontinued. METHODS: > Mice > allergic to peanut treated with FAHF-2 for 7 weeks were challenged > 1, 3, or > 5 weeks posttherapy. Anaphylactic scores, core body temperatures, > vascular > leakage, and plasma histamine levels after peanut challenge were > determined. > Serum peanut-specific antibody levels and splenocyte cytokine > profiles were > also measured. RESULTS: After challenges, all sham-treated mice > developed > severe anaphylactic signs, significant decrease in rectal > temperatures, > significantly increased plasma histamine levels, and marked vascular > leakage. In contrast, no sign of anaphylactic reactions, decrease > in rectal > temperatures, or elevation of plasma histamine levels was observed in > FAHF-2-treated mice in 5 separate experiments. IgE levels were > significantly > reduced by FAHF-2 treatment and remained significantly lower as > long as 5 > weeks posttherapy. Splenocytes from FAHF-2-treated mice showed > significantly > reduced IL-4, IL-5, and IL-13, and enhanced IFN-gamma production to > recall > peanut stimulation in vitro . CONCLUSION: FAHF-2 treatment completely > eliminated anaphylaxis in mice allergic to peanut challenged as > long as 5 > weeks posttherapy. This result was associated with downregulation > of T H 2 > responses. FAHF-2 may be a potentially effective and safe therapy > for peanut > allergy. > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 29, 2007 Report Share Posted October 29, 2007 Interesting. It¹s a variation of wu mei wan Cara O. Frank, R.OM, Dipl Ac & Ch.H. Six Fishes Healing Arts & President China Herb Company of the Chinese Herb Program Tai Sophia Institute of the Healing Arts 215-772-0770 " David Russell, L.Ac. " <dave Mon, 29 Oct 2007 09:55:28 -0700 Re: Allergy Formula This formula is as follows: ling zhi (ganoderma lucidum), 28.17% wu mei (fructus pruni mume), 28.17% huang lian (rhizoma coptidis), 8.46% ren shen (radix ginseng), 8.45% huang bai (cortex phellodendri), 5.63% gan jiang (rhizoma zingiberis officinalis), 8.45% dang gui (radix angelicae sinensis), 8.45% gui zhi (ramulus cinnamomi cassiae), 2.81% chuan jiao (pericarpium zanthoxyli bungeanum), 1.41% You can read about it at the end of the following article. http://www.acupuncturetoday.com/mpacms/at/article.php?id=30254 David Russell, L.Ac., CMT Russell Family Acupuncture 134 Howard Street Petaluma, CA 94952 707.773.3375 www.acuherbal.com On Oct 27, 2007, at 6:22 AM, Nashua Acupuncture wrote: > Hi Sean, > > It will be interesting to see if that info is available. I believe > they are working on a patent for this formula. > > Cheers, > Michael > > - > Sean Doherty > <%40> > Friday, October 26, 2007 3:50 PM > Allergy Formula > > Does anyone know what the ingredients of this formula are? Zai Zao San > maybe? > > Thanks, > > Sean > > The Chinese herbal medicine formula FAHF-2 completely blocks > anaphylactic > reactions in a murine model of peanut allergy. > Srivastava KD,Kattan JD,Zou ZM,Li JH, Zhang L, Wallenstein S,Goldfarb > J,Sampson HA,Li XM. > Department of Pediatrics, Mount Sinai School of Medicine, New York, NY > 10029-6574, USA. > > BACKGROUND: Peanut allergy is potentially life threatening. There > is no > curative therapy for this disorder. We previously found that an herbal > formula, food allergy herbal formula (FAHF)-1, blocked peanut-induced > anaphylaxis in a murine model when challenged immediately posttherapy. > OBJECTIVE: To test whether FAHF-2, an improved herbal formula, from > which 2 > herbs, Zhi Fu Zi (Radix Lateralis Aconiti Carmichaeli Praeparata) > and Xi Xin > (Herba Asari), were eliminated, is equally effective to FAHF-1, and > if so, > whether protection persists after therapy is discontinued. METHODS: > Mice > allergic to peanut treated with FAHF-2 for 7 weeks were challenged > 1, 3, or > 5 weeks posttherapy. Anaphylactic scores, core body temperatures, > vascular > leakage, and plasma histamine levels after peanut challenge were > determined. > Serum peanut-specific antibody levels and splenocyte cytokine > profiles were > also measured. RESULTS: After challenges, all sham-treated mice > developed > severe anaphylactic signs, significant decrease in rectal > temperatures, > significantly increased plasma histamine levels, and marked vascular > leakage. In contrast, no sign of anaphylactic reactions, decrease > in rectal > temperatures, or elevation of plasma histamine levels was observed in > FAHF-2-treated mice in 5 separate experiments. IgE levels were > significantly > reduced by FAHF-2 treatment and remained significantly lower as > long as 5 > weeks posttherapy. Splenocytes from FAHF-2-treated mice showed > significantly > reduced IL-4, IL-5, and IL-13, and enhanced IFN-gamma production to > recall > peanut stimulation in vitro . CONCLUSION: FAHF-2 treatment completely > eliminated anaphylaxis in mice allergic to peanut challenged as > long as 5 > weeks posttherapy. This result was associated with downregulation > of T H 2 > responses. FAHF-2 may be a potentially effective and safe therapy > for peanut > allergy. > > Quote Link to comment Share on other sites More sharing options...
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