Chinese herbs in fracture-healing in elderly people

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Chen SX, Kang L, Chen HQ, Situ J, Zhao CD, Ding LJ, Liu HG. [Clinical

randomized controlled trial on splint external fixation combined with

Chinese herbs in treating distal radius fractures of elderly

patients] [Article in Chinese] Zhongguo Gu Shang. 2008 Mar;21(3):181-

3. Department of Orthopaedics, Wuyi TCM Hospital of Jiangmen City,

Jiangmen 529031, Guangdong, China. csxhome OBJECTIVE: To

explore the effects of Yishen Zhuanggu decoction,YSZGD) on fracture

healing and function of wrist joint in osteoporotic distal radius

fractures (ODRF) of elderly patients. METHODS: Ninety patients of

ODRF were treated with splint external fixation and YSZGD, including

28 males and 62 females, with an average age of 63 years (ranged, 61-

91 years). According to AO classification, all the patients were

classified as type A or B1. Among the patients, 80 patients had a

type of Colles fracture,7 patients were with a type of Smith

fracture,and 3 patients had a type of Barton fracture. They were

randomly divided into three groups included TCM, Western medicine and

control group (30 cases each group) after the fractures were fixed

manually by splint. Patients in TCM group took YSZGD orally, one

potion and two time each day; the patients in Western medicine group

treated with Calcitonin (50 units, intramuscular, 2 times each week),

Caltrate D (1 tablets, taken orally, one time each day) and

Alfacalcidol Soft Capsules (0.5 units, taken orally, one time each

day); and the patients in control group took no medicine. X-ray

examination on the fractured wrist was taken at the 4, 6, 8, 12th

weeks after treating to observe, the fracture healings, the

evaluation of wrist function and comparision of curative effects were

taken at the 2nd month. RESULTS: The fracture healing time in TCM

group was 7.12 +/- 2.32 weeks and that in the Western medicine group

was 9.25 +/- 3.05 weeks, showing significant differences between them

(PC < 0.05), and that in the control group was 11.57 +/- 1.93 weeks

which was longer thant in that in the two medicine groups (P < 0.05);

According to Dienst wrist rating system, the excellent and good rates

of three groups were 93.3%, 86.7% and 60% respectively which showing

significant differences between medicine groups and control group (P

< 0.05), and the curative effects of medicine groups were more

excellent than that of control group through Ridit analysis.

CONCLUSION: YSZGD can promote the fracture healing evidently and

shorten the healing time, whose curative effect surpassed Western

medicine and promoted the restoration of wrist function. PMID:

19105432 [PubMed - indexed for MEDLINE]

 

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