Guest guest Posted February 11, 2009 Report Share Posted February 11, 2009 Hi All, Zhou J, Qu F, Sang X, Wang X, Nan R. AP and Auricular Acupressure in Relieving Menopausal Hot Flashes of Bilaterally Ovariectomized Chinese Women: A Randomized Controlled Trial. Evid Based Complement Alternat Med. 2009 Feb 2. [Epub ahead of print] No. 604 Room in B Building, School of Med, Zhejiang Univ, 388 Yuhang Tang Road, Hangzhou, Zhejiang 310058, China. qufan43 The objective of this study is to explore the effects of AP and auricular acupressure in relieving menopausal hot flashes of bilaterally ovariectomized Chinese women. Between May 2006 and March 2008, 46 bilaterally ovariectomized Chinese women were randomized into an AP and auricular acupressure group (n = 21) and a hormone replacement therapy (HRT) group (Tibolone, n = 25). Each patient was given a standard daily log and was required to record the frequency and severity of hot flashes and side effects of the treatment felt daily, from 1 week before the treatment started to the fourth week after the treatment ended. The serum levels of follicle stimulating hormone (FSH), LH and E(2) were detected before and after the treatment. After the treatment and the follow-up, both the severity and frequency of hot flashes in the two groups were relieved significantly when compared with pre-treatment (P < 0.05). There was no significant difference in the severity of hot flashes between them after treatment (P > 0.05), while after the follow-up, the severity of hot flashes in the HRT group was alleviated more. After the treatment and the follow-up, the frequency of menopausal hot flashes in the HRT group was reduced more (P < 0.05). After treatment, the levels of FSH decreased significantly and the levels of E(2) increased significantly in both groups (P < 0.05), and they changed more in the HRT group (P < 0.05). AP and auricular acupressure can be used as alternative treatments to relieve menopausal hot flashes for those bilaterally ovariectomized women who are unable or unwilling to receive HRT. PMID: 19189989 [PubMed - as supplied by publisher] Kim ES, Kang JY, Pyo CH, Rhee GW. Treatment of Pneumothorax Following AP: Is a Closed Thoracostomy Necessary for a First Choice of Treatment Modality? J Altern Complement Med. 2009 Jan 28. [Epub ahead of print] Dept of Thoracic and Cardiovascular Surgery, Hanil General Hospital, KEPCO Med Foundation, Seoul, Republic of Korea. Abstract Background: AP is currently the most popular of all forms of complementary and alternative Med, and AP is not dangerous in the hands of a trained practitioner. However, complications of AP including pneumothorax have been reported. Objectives: Despite the use of fine needles in AP, the lung-collapsed degree of AP pneumothorax is relatively high. In general, the treatment modality of AP pneumothorax is closed thoracostomy with a chest tube of larger diameter. However, the treatment of AP pneumothorax frequently faces controversy concerning the necessity of a standard chest drain insertion. Design: This was a retrospective study from March 1994 to February 2004. Subjects: Nine (9) patients were admitted due to pneumothorax following AP from March 1994 to February 2004 in Hanil General Hospital, KEPCO Med Foundation (Seoul, Republic of Korea). Results: Five patients had a moderate degree of pneumothoraces, while 4 patients had a severe degree of pneumothoraces. Four patients were treated by closed thoracostomy with a standard chest drain and the other four patients were treated by the percutaneous chest drainage with a narrow-bore central venous catheter. One patient with a mild degree of pneumothorax was treated only by nasal oxygen inhalation. One patient was treated by video-assisted thoracic surgery after the closed thoracostomy due to continuous air leak. Conclusions: We treated the AP pneumothorax by making a choice between the closed thoracostomy and the percutaneous chest drainage based on a smoking history and chest radiographic findings. In the absence of smoking history and pulmonary emphysema or bullae, we got favorable results, not by the closed thoracostomy but only by the percutaneous chest drainage with a narrow-bore central venous catheter. PMID: 19196054 [PubMed - as supplied by publisher] Huang GY, Zheng CH, Yu WC, Tian DS, Wang W. Involvement of connexin 43 in AP analgesia. Chin Med J (Engl). 2009 Jan 5;122(1):54-60. Institute of Integrated Traditional and Western Med, Tongji Hospital, Tongji Med Coll, Huazhong Univ of Science and Technology, Hubei, China. BACKGROUND: Connexin 43 (Cx43) is one of the major components of human keratinocyte gap junctions. To study whether gap junctional intercellular communication participates in the transfer of acupoint signals and AP analgesia, the expression of Cx43 was studied in Zusanli (ST36) acupoints compared with control non-acupoint regions in rats after AP. In addition, Cx43 heterozygous gene knockout mice were used to further explore the relationship between Cx43 and AP analgesia. METHODS: The expression of Cx43 was detected by immunohistochemistry, immunoblotting, and RT-PCR for the Cx43 protein and mRNA. The influence of the Cx43 gene knockout on AP analgesia was measured by a hot plate and observing the writhing response on Cx43 heterozygous gene knockout mice. RESULTS: Immunohistochemistry showed abundant Cx43 expression in some cells in the skin and subcutaneous tissue of rat ST36 acupoints. The mRNA and protein levels of Cx43 in acupoints were significantly higher than those in the control points in the non-AP group, and even more so after AP. The hot plate and writhing response experiments showed that partial knockout of the Cx43 gene decreased AP analgesia. CONCLUSION: Cx43 expression and AP analgesia showed a positive correlation. Publication Types: Research Support, Non-U.S. Gov't PMID: 19187618 [PubMed - in process] Xu J, Niu YX, Piao XM, Liu Z, Wu LZ, Liang RL. [Effect of AP on blood oxygen saturation in patients of obstructive sleep apnea-hypopnea syndrome] [Article in Chinese] Zhongguo Zhen Jiu. 2009 Jan;29(1):84- 6. Yueyang Hospital of Integrated Chinese Med and Western Med, Affiliated to Shanghai Univ of TCM, Shanghai 200437, China. maiyixu OBJECTIVE: To investigate the effect of AP on blood oxygen saturation in the patient of obstructive sleep apnea-hypopnea syndrome (OSAHS) in sleeping and to evaluate the therapeutic effect of AP on this disease. METHODS: Thirty cases with OSAHS were treated with AP at Shanglianquan (Extra), Fengfu (GV 16), Yamen (GV 15), Fengchi (GB 20), etc. 3-5 sessions each week. After treatment of 30 sessions, apneahypopnea index (AHI), mean blood oxygen saturation (MSaO2), the lowest blood oxygen saturation (LSaO2), oxygen desaturation > or = 4% index (ODI4), the mean blood oxygen saturation of oxygen desaturation when SaO2 < 90%, the longest time of oxygen saturation > or = 4% were observed before and after treatment. RESULTS: The effective rate of AP was 23.3% for OSAHS. After AP, AHI and ODI4 significantly reduced (P < 0.01); LSaO2 significantly increased (P < 0.01); MSaO2 and the mean blood oxygen saturation of oxygen desaturation when SaO2 < 90% significantly enhanced (P < 0.05); the longest time of oxygen saturation > or = 4% did not significantly change. CONCLUSION: The AP treatment has intervenient effect on OSAHS and alleviates anoxia, so AP is one of therapies improving anoxia in patients of OSAHS. Publication Types: English Abstract PMID: 19186731 [PubMed - in process] Xu KS, Huang MW, Yao LY, Chen J, Su J, Zheng JQ. [Clinically randomized controlled trials of moxibustion with salt in bamboo circle for treatment of periarthritis of shoulder] [Article in Chinese] Zhongguo Zhen Jiu. 2009 Jan;29(1):77-80. Dept of AP and Moxibustion, Affiliated Hospital of Putian Coll, Putian, Fujian 351100, China. xks20052008 OBJECTIVE: To assess the clinical therapeutic effect of moxibustion with salt in bamboo circle on periarthritis of shoulder. METHODS Eighty-six cases were randomly divided into a salt-moxibustion group and an electroAP group, 43 cases in each group. The salt-moxibustion group was treated by moxibustion with salt in bamboo circle on the part of obvious pain and hot compress moxibustion on its periphery. The electroAP group was treated with electroAP at Jianyu (LI 15), Jianliao (TE 14), Jianzhen (SI 9), etc. After treatment, the analgesic effect and improvement degrees of active function of the shoulder joint were observed and 3 months later they were followed-up. RESULTS: The two therapies had analgesic effect and could improve active function of shoulder joint, but the salt-moxibustion group in the transient analgesic effect and the improvement degree of active function of the shoulder joint was better than the electroAP group (P< 0.01, P < 0.05). Follow-up survey showed good clinical therapeutic effects in the two groups. The effective rates of pain and active function of shoulder joint were 97.7% and 93.0% in the salt-moxibustion group and 93.0% and 88.4% in the electroAP group, respectively, with no significant differences between the two groups. CONCLUSION: Moxibustion with salt in bamboo circle has an obvious therapeutic effect on periarthritis of shoulder, and it has transient analgesic effect and improves active function of shoulder joint, with a stable and long-term therapeutic effect. Publication Types: English Abstract PMID: 19186729 [PubMed - in process] Reheman A, Liu HS, Kang MF. [Clinical study on AP combined with moxibustion on temperature-sensitive points for treatment of Bell palsy in the acute stage] [Article in Chinese] Zhongguo Zhen Jiu. 2009 Jan;29(1):17-20. Dept of Rehabilitation, Affiliated Hospital of Xinjiang Uygur Higher Med Training School, Hetian 848000, China. kuyax1969 OBJECTIVE: To probe into a new therapy with less pain, good therapeutic effect and convenience for facial palsy in acute stage. METHODS: Sixty cases were randomly divided into 2 groups, an observation group and a control group, 30 cases in each group. The observation group was treated with routine AP plus moxibustion on temperature-sensitive points, and the control group with the routine AP. Their therapeutic effects were assessed by the criteria for assessment of facial nerve function stipulated by Japanese Institute for Researching the Facial Nerve in 1997. RESULTS: There were significant differences in cumulative scores of symptoms before and after treatment in the two groups (both P < 0.01) and there was a significant difference in the cumulative score of symptoms after treatment between the two groups (P < 0.01). The cured rate was 76.67% in the observation group and 50.00% in the control group with a significant difference between the two groups (P < 0.05). The total effective rates were respectively 93.33% and 76.67% in the two groups with no significant difference between the two groups (P > 0.05). CONCLUSION: Both AP combined with moxibustion on temperature-sensitive points and simple AP have good therapeutic effects on idiopathic facial palsy, but the observation group is better than the control group. Publication Types: English Abstract PMID: 19186716 [PubMed - in process] Zhao XP, Chen RX, Lü HQ. [influence of garlic moxibustion on the therapeutic effect in re-treatment patients of tuberculosis] [Article in Chinese] Zhongguo Zhen Jiu. 2009 Jan;29(1):10-2. Dept of TCM, Chest Hospital of Qingdao City, Qingdao, Shandong 266043, China. OBJECTIVE: To observe the therapeutic effect of moxibustion in re- treatments patients of tuberculosis. METHODS: Fifty-three cases were randomly divided into an observation group (n = 31) and a control group (n = 22). They were treated with routine chemotherapeutic program of western Med with garlic moxibustion on main points Feishu (BL 13), Gaohuang (BL 43), Shenzhu (GV 12), etc. added in the observation group. The therapeutic effects were assessed by clinical symptoms and signs, X-ray, CT examination and laboratory indexes. RESULTS: The focus absorbing rate of 87.1% in the observation group was better than 63.6% in the control group (P < 0.05); the rate of bacteria-turned negativity in sputum was 90.5% in the observation group which was better than 56.3% in the control group (P < 0.05); the observation group in improvement of hypodynamia, night sweat and cough was superior to the control group (all P < 0.05). CONCLUSION: Moxibustion can increase the therapeutic effect for the re-treatment patient of tuberculosis. Publication Types: English Abstract PMID: 19186714 [PubMed - in process] Sima L, Wang X. [Therapeutic effect of AP on cisplatin-induced nausea and vomiting] [Article in Chinese] Zhongguo Zhen Jiu. 2009 Jan;29(1):3-6. National Pain Management and Research Center, China- Japan Friendship Hospital, Beijing 100029, China. simalei OBJECTIVE: To observe therapeutic effect of AP combined with antiemetic on cisplatin-induced nausea and vomiting. METHODS: By using paired, cross-controlled trial design, 66 cases of chemotherapy were divided into group A and B, 33 cases in each group. For the group A, chemotherapy, tropisetron and AP therapy were adopted in the first chemotherapy cycle and the same chemotherapy program, tropisetron and sham AP were used in the next cycle. For the group B, chemotherapy, tropisetron and sham AP were given in the first chemotherapy cycle and the same chemotherapy program, tropisetron and AP therapy were applied in the next cycle. Zusanli (ST 36), Neiguan (PC 6) and Gongsun (SP 4) and auricular point Wei (stomach) were selected for AP therapy, and the points at 3 cm lateral to Zusanli (ST 36) , Neiguan (PC 6) and Gongaun (SP 4) and auricular point corresponding to scapha level were selected for sham AP. AP treatment or sham-AP was given for 6 consecutive days, once each day and antiemetic tropisetron 5 mg was given to the two groups as basic antiemetic prophylaxis for 6 days, once daily. The therapeutic effects on nausea and vomiting in the 6 days were compared between the AP group and the sham-AP group in the two chemotherapeutic cycles. RESULTS: The effective rates for nausea in the 2nd day and the 4th day were 87.1% and 79.0% in AP group, which were superior to 59.4% and 57.8% in the sham-AP group, respectively (both P < 0.05); and the therapeutic effects on vomiting in the 3rd-6th day in the AP group were better than those in the sham-AP group (P < 0.05). CONCLUSION: AP combined with antiemetic can effectively decrease the incidence and degree of cisplatin-induced delayed nausea and vomiting. The effect of AP is better than that of sham AP. Publication Types: English Abstract PMID: 19186712 [PubMed - in process] Qian XP, Xu F, Song JL, Zhao JH. [influence of different frequencies of AP on therapeutic effect in patients with cerebral infarction at convalescence] [Article in Chinese] Zhongguo Zhen Jiu. 2009 Jan;29(1):7-9. Dept of TCM, The Fourth Affiliated Hospital of Neimonggu Med Coll, Baotou 014030, China. qianxiaoping2000 OBJECTIVE: To observe the influence of different frequencies of AP on the therapeutic effect in patients with cerebral infarction at convalescence. METHODS: Ninety-seven cases were randomly divided into an observation group I (n = 50) and an observation group II (n = 47). They were treated with same Chinese drugs and western Med and electroAP at Jiquan (HT 1), Quchi (LI 11), Hegu (LI 4), Huantiao (GB 30), etc. The observation group I was treated twice each day and the observation group II once each day. After treatment of 30 days, their therapeutic effects were observed. RESULTS: The total effective rate of 94.0% for improvement of limb activity in the observation group I was better than 78.7% in the observation group II (P < 0.05); the therapeutic effects for choking when taking water, dysphagia, vague mind and slurred speech were similar in the two groups (P > 0.05). CONCLUSION: The therapeutic effect of AP twice each day on cerebral infarction at convalescence is superior to that of once daily. Publication Types: English Abstract PMID: 19186713 [PubMed - in process] Puangsricharern A, Mahasukhon S. Effectiveness of auricular acupressure in the treatment of nausea and vomiting in early pregnancy. J Med Assoc Thai. 2008 Nov;91(11):1633-8. Dept of Obstetrics and Gynecology, Rajavithi Hospital, Coll of Med, Rangsit Univ, Bangkok, Thailand. OBJECTIVE: To evaluate the effectiveness of auricular acupressure in the treatment of nausea and vomiting in early pregnancy. MATERIAL AND METHOD: Ninety-eight volunteer pregnant women with symptoms of nausea and vomiting in early pregnancy before 14 weeks gestation were enrolled. The participants were randomized into two groups: treatment group and control group. Each patient in the treatment group received magnet pellets, placed at both auricles. They were taught to start acupressure from the third to the sixth day. Outcome measurement was Rhodes index score, which describe the severity and frequency of nausea and vomiting in the form of a questionnaire. The patients from both groups were asked to complete and return the forms including the amount of anti-emetic drug taken. Mean Rhodes index score and total number of anti-emetic drug taken from day 4-6 were used to compare the treatment effect. Student's t test, Chi-square test and Mann-Whitney U test were used for statistical analysis. RESULTS: Ninety-one pregnant women who returned the questionnaires were evaluated. The Rhodes index scores of the treatment group were lower than that of the control group especially after day 4 to day 6 when the acupressure was started. However when comparing the mean score between the two groups, there were no statistically significant differences (p > 0.05). The total amount of anti-emetic tablets in day 4-6 after acupressure intervention was compared and there were no statistically significant differences (p > 0.05) between the groups. CONCLUSION: Auricular acupressure therapy in treatment of nausea and vomiting in early pregnancy may not relieve nausea and vomiting in early pregnancy and need further clinical research to confirm the effectiveness. Publication Types: Clinical Trial Comparative Study Randomized Controlled Trial PMID: 19127781 [PubMed - indexed for MEDLINE] Enblom A, Hammar M, Steineck G, Börjeson S. Can individuals identify if needling was performed with an AP needle or a non-penetrating sham needle? Complement Ther Med. 2008 Oct;16(5):288-94. Dept of Med and Health Sciences, Division of Nursing Science, Linköping Univ, Sweden. anna.enblom A control treatment in AP research must be credible, regardless if the needling is performed by one or by several therapists. OBJECTIVE: To investigate if individuals could identify whether needling had been given with an AP needle or a sham needle and if the therapist influenced this ability. DESIGN: Eighty individuals were randomized to one single needling given by one of four physiotherapists using either an invasive needle or a non- penetrating telescopic sham needle. RESULTS: An equal proportion of individuals, 27 (68%), in the AP group and the sham group answered incorrectly or was not sure at all regarding needling type but the proportion varied between the therapists from 55 to 80% (ns). Bang's blinding index was 0.20 (95% CI 0.03-0.36) in the AP group and 0.10 (95% CI 0.09-0.29) in the sham group (interpretation: 20 and 10% identified needling type beyond statistical chance). AP was on a four- grade scale rated as median " mildly painful " and sham as " not painful " (ns). Pain ratings varied from median " not " to " mildly painful " in the therapists (p = 0.01). CONCLUSIONS: Two thirds of individuals needled by AP as well as sham could not identify needling type and only 10-20% of the individuals were unblinded beyond chance. The therapists, not the needling type, influenced how painful the needling was perceived. IMPLICATIONS: To achieve blinding success in AP efficacy studies using the sham needle, the needling procedure must be strictly standardized in order to minimize differences between the therapists. Publication Types: Research Support, Non-U.S. Gov't PMID: 19186344 [PubMed - in process] Li W, Cobbin D, Zaslawski C. A comparison of effects on regional pressure pain threshold produced by deep needling of LI4 and LI11, individually and in combination. Complement Ther Med. 2008 Oct;16(5):278-87. Coll of TCM, Faculty of Science, Univ of Technology, Sydney, Australia. Dr.liweihong OBJECTIVES: To compare the effects of unilateral and bilateral needling of the same acupoint, and the effects of individual and combined needling of two distinct acupoints on pressure pain threshold (PPT). DESIGN: 22 subjects completed the randomised, dual blind (subject and evaluator) repeated measures study. PPT was measured before and after each intervention at ten sites (acupoints and nonacupoints) across the body with an algometer. Interventions: The same manual AP techniques were applied to four interventions of large intestine 4 (LI4) unilaterally; LI4 bilaterally; large intestine 11 (LI 11) unilaterally; and LI4 in conjunction with LI11, both unilaterally. MAIN OUTCOME MEASURES: (1) Percentage change in PPT from preintervention baseline measured at the 10 regional sites following every intervention; (2) participants' perceptions of pain; needling sensations; tension during, and anxiety prior to, each intervention; and changes in practitioner behaviour. RESULTS: Following all four interventions, statistically significant increases in mean PPT were observed. These occurred at nine sites following the LI4 intervention either unilaterally or bilaterally; at six sites for LI11 intervention; and at five sites following the combined LI11 and LI4 intervention. These increases were significantly greater for the bilateral LI4 intervention than the unilateral LI4 intervention at only two sites (p < 0.02 and p < 0.0001). There were no statistically significant differences in the subjective perceptions among the four interventions. CONCLUSION: The enhanced effects on PPT by the bilateral compared with the unilateral intervention at LI4 although limited, do provide some support for the TCM assumption that bilateral needling of the same point enhances the treatment effect. There was no support for the assumption that combined needling of points from the same channel should enhance the treatment effect and failure to obtain better effects by combined needling of points from the same channel could result from the interaction occurring during the combined needling. PMID: 19186343 [PubMed - in process] Choi KH, Hill SA. AP treatment for feline multifocal intervertebral disc disease. J Feline Med Surg. 2009 Jan 29. [Epub ahead of print] Complementary and Alternative Med, Dept of Vet Clinical Sciences, Coll of Vet Sciences, Univ of Minnesota, St. Paul, MN 55108, USA. A 14-year-old male neutered domestic shorthair cat was admitted to the Vet Med Center, Univ of Minnesota for evaluation of severe hind limb ataxia, atrophy and paresis. Diagnosis based on physical examination, neurological assessment and magnetic resonance imaging (MRI) was multifocal intervertebral disc disease (IVDD) with dorsal disc protrusion throughout the thoracic and cranial lumbar spine. The Oriental Med (OM) diagnosis (pattern identification) was painful obstruction (Bi) syndrome caused by phlegm-heat accumulation with blood stagnation in the spine. High dose prednisolone therapy (1.25mg/kg PO, once daily) initially did not show any significant improvement in clinical signs. The cat was then treated with several modes of AP treatment including dry needle AP, electro-AP and scalp AP along with Tui-Na (hand manipulation in OM) and physical therapy. Significant improvements in mobility, proprioception and spinal posture were noticed and the cat was able to rise, walk and run 4 months after starting AP treatments. This is the first case report of feline IVDD with multiple sites of disc compression which was successfully treated with several modes of AP treatment. PMID: 19186087 [PubMed - as supplied by publisher] PHIL'S COMMENT: n = 1, with no control. Also, 4 months is a very long time to cure and recovery could have been unrelated to treatment. Lund I, Naslund J, Lundeberg T. Minimal AP is not a valid placebo control in randomised controlled trials of AP: a physiologist's perspective. Chin Med. 2009 Jan 30;4(1):1. [Epub ahead of print] ABSTRACT: Placebo-control of AP is used to evaluate and distinguish between the specific effects and the non-specific ones. During 'true' AP treatment in general, the needles are inserted into acupoints and stimulated until deqi is evoked. In contrast, during placebo AP, the needles are inserted into non-acupoints and/or superficially (so- called minimal AP). A sham AP needle with a blunt tip may be used in placebo AP. Both minimal AP and the placebo AP with the sham AP needle touching the skin would evoke activity in cutaneous afferent nerves. This afferent nerve activity has pronounced effects on the functional connectivity in the brain resulting in a 'limbic touch response'. Clinical studies showed that both AP and minimal AP procedures induced significant alleviation of migraine and that both procedures were equally effective. In other conditions such as low back pain and knee osteoarthritis, AP was found to be more potent than minimal AP and conventional non-AP treatment. It is probable that the responses to 'true' AP and minimal AP are dependent on the aetiology of the pain. Furthermore, patients and healthy individuals may have different responses. We argue that minimal AP is not valid as an inert placebo-control despite its conceptual brilliance. Publication Types: EDITORIAL PMID: 19183454 [PubMed - as supplied by publisher] Chen ZX. [Control study on AP and medication for treatment of primary simple premature ejaculation] [Article in Chinese] Zhongguo Zhen Jiu. 2009 Jan;29(1):13-5. Dept of Rehabilitation, Central Hospital of Sanmenxia City, Sanmenxia, Henan 472000, China. czxdoctor OBJECTIVE: To compare therapeutic effects of AP and medication on primary simple premature ejaculation. METHODS: One hundred and eleven cases were randomly divided into an AP group (n = 56) and a medication group (n = 55). The AP group was treated by AP with acupoint group I Xinshu (BL 15), Ganshu (BL 18), Pishu (BL 20), Shenshu (BL 23) and acupoint group II Guanyuan (CV 4), Zhongji (CV 3), Sanyinjiao (SP 6), Taixi (KI 3), Taichong (LR 3) alternately selected, one acupoint group daily. The medication group was treated with oral administration of Sailete tablets, 20 mg each tablet, one tablet each night. After they were treated for one course, their therapeutic effects were compared. RESULTS: The total effective rate was 82.1% in the AP group and 63.6% in the medication group; the cumulative score after treatment was 12.56 +/- 3.84 in the AP group and 11.50 +/- 3.77 in the medication group, with a significant difference between the two groups in the therapeutic effect (P < 0.05). CONCLUSION: AP has a better therapeutic effect on primary simple premature ejaculation. Publication Types: English Abstract PMID: 19186715 [PubMed - in process] PHIL'S COMMENT: Sailete [Citalopram Hydrobromide] is an SSRI antidepressant http://tinyurl.com/cybq6s and http://tinyurl.com/bg9kws As with other SSRIs, there are reports of sexual dysfunction (decreased libido, anorgasmia, ejaculation dysfunction, impotence) in both men and women taking citalopram. See http://www.medscape.com/viewarticle/417985_8 However, it also is used to TREAT premature ejaculation. See http://www.nature.com/ijir/journal/v14/n6/full/3900918a.html Best regards, Quote Link to comment Share on other sites More sharing options...
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