Recent Medline Abstracts on acupuncture

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Acta Anaesthesiol Scand. 2009 Aug 13. [Epub ahead of print] Effect of P6

acustimulation on post-operative nausea and vomiting in patients

undergoing a laparoscopic cholecystectomy. Frey UH, Funk M, Löhlein C,

Peters J. Klinik für Anästhesiologie und Intensivmedizin, Universität

Duisburg-Essen, Essen, Germany. Background Non-pharmacologic

techniques such as acupoints electrostimulation (AES) may mitigate post-

operative nausea and vomiting (PONV). The primary purpose of this study

was to investigate the effectiveness of AES on attenuating PONV.

Moreover, we tested whether a pre- or a post-induction application of AES

results in differences in PONV reduction. Methods In a prospective, double-

blind, randomized, controlled trial, we studied 200 patients undergoing a

laparoscopic cholecystectomy during propofol (induction)

fentanyl/isoflurane/atracurium (maintenance) anaesthesia. In the AES group

(n=101), subdivided into groups with pre-induction (n=57) and post-induction

(n=44) AES, an active ReliefBand(®) device was placed at PC06 [Phil: see

http://www.aeromedix.com/aeromedix_articles/reliefband/index.html ]. In the

sham group (n=99), also subdivided into pre-induction (n=55) or post-

induction (n=44) groups, an inactive device was applied instead. The

ReliefBand(®) remained in place for 24 h after surgery. Nausea and

vomiting/retching were recorded at 2, 6, and 24 h post-operatively. Results

The incidence of early nausea (up to 2 h) was significantly lower in the AES

than in the sham group (29% vs. 42%; P=0.043). No significant effect could

be detected for retching/vomiting. Moreover, AES showed no effect on

PONV after 6 and 24 h. Risk factor analysis (female gender, non-smoker,

history of PONV/motion sickness, and post-operative morphine usage)

revealed a relative reduction in risk of 40% for nausea (P=0.021) and 55%

for retching/vomiting (P=0.048) in patients with three or four risk factors

present. The timing of (pre- vs. post-induction) AES had no significant effect

on PONV reduction. Conclusion: AES at PC06 reduces early nausea, but

not vomiting, after laparoscopic cholecystectomy, irrespective of its pre- or

post-induction application. PMID: 19681777 [PubMed - as supplied by

publisher]

 

Adv Gerontol. 2008;21(3):424-6. [Effectiveness of laser puncture in elderly

patients with bronchial asthma accompanied by chronic rhinosinusitis]

[Article in Russian] Nikitin AV, Esaulenko IE, Shatalova OL. We apply laser

puncture to influence biological active points with infra red laser ionizing at

scheme with effect of treatment of asthma bronchial with chronic

accompanied by rhino sinusitis. The clinical effectiveness of treatment was

seen in positive dynamics of clinical, instrumental and spirographycal

indices regarding bronchial asthma and concomitant rhinitis as well, which

was confirmed by X-ray examination. Application of laser punctureto treat

the elderly patients with asthma bronchial accompanied by rhino sinusitis is

an effective method having no side effects that can be used in an

ambulatory and in a hospital. Publication Types: * English Abstract PMID:

19432177 [PubMed - indexed for MEDLINE]

 

Clin J Pain. 2009 Sep;25(7):624-31. A single point acupuncture treatment at

large intestine meridian: a randomized controlled trial in acute tonsillitis and

pharyngitis. Fleckenstein J, Lill C, Lüdtke R, Gleditsch J, Rasp G, Irnich D.

Multidisciplinary Pain Center, Department of Anesthesiology, University of

Munich, Pettenkoferstr 8A, 80336 München, Germany. OBJECTIVES: 25%

of patients visiting a general practitioner reports of a sore throat associated

with pain on swallowing. This study was established to examine the

immediate pain alleviating effect of a single point AP treatment applied to

the large intestine meridian of patients with sore throat. PATIENTS AND

METHODS: Sixty patients with acute tonsillitis and pharyngitis were enrolled

in this randomized placebo-controlled trial. They either received AP, or sham

laser AP, directed to the large intestine meridian section between AP points

LI08 and LI10. The main outcome measure was the change of pain intensity

on swallowing a sip of water evaluated by a visual analog scale 15 minutes

after treatment. A credibility assessment regarding the respective treatment

was performed. RESULTS: The pain intensity for the AP group before and

immediately after therapy was 5.6+/-2.8 and 3.0+/-3.0, and for the sham

group 5.6+/-2.5 and 3.8+/-2.5, respectively. Despite the articulation of a

more pronounced improvement among the AP group, there was no

significant difference between groups (Delta=0.9, confidence interval: -0.2-

2.0; P=0.12; analysis of covariance). Patients' satisfaction was high in both

treatment groups. The study was terminated prematurely due to a

subsequent lack of suitable patients. DISCUSSION: A single AP treatment

applied to a selected area of the large intestine meridian was no more

effective in the alleviation of pain associated with clinical sore throat than

sham laser AP applied to the same area. Clinically relevant improvement

could be achieved in both groups. Pain alleviation might partly be due to the

intense palpation of the large intestine meridian. The benefit of a

comprehensive AP treatment protocol in this condition should be subject to

further trials. Publication Types: * Research Support, Non-U.S. Gov't PMID:

19692805 [PubMed - in process]

 

Clin Microbiol Infect. 2009 Aug 20. [Epub ahead of print] An outbreak of skin

and soft tissue infection caused by Mycobacterium abscessus following

acupuncture. Koh SJ, Song T, Kang YA, Choi JW, Chang KJ, Chu CS,

Jeong JG, Lee JY, Song MK, Sung HY, Kang YH, Yim JJ. Epidemic

Intelligence Service, Division of Public Health and Hygiene Policy, Gyeonggi

Provincial Office, Republic of Korea. Abstract Although outbreaks of

Mycobacterium abscessus infection have been reported, none of these

reports have identified the potential sources of infection and modes of

transmission. In April 2008, we identified and investigated an outbreak of M.

abscessus skin and soft tissue infections following AP among the patients

who visited an oriental medical clinic. Active surveillance of patients who had

visited the clinic was conducted to define the extent of the outbreak.

Environmental cultures and a case-control study were performed to

elucidate the source of infection and mode of transmission. From 1,002

patients interviewed, 109 patients were identified to have suffered M.

abscessus skin and soft tissue infections at AP sites. A single strain of M.

abscessus was isolated from the wounds of 31 patients and nine

environmental samples, including a diluted glutaraldehyde solution. The

case-control study revealed that a higher numbers of visits to the clinic for

AP (aOR, 20.12; 95% CI 4.34-93.35) and the use of interferential current

therapy or low-frequency therapy (aOR, 36.12; 95% CI, 5.54-235.44) were

associated with the development of M.abscessus infection. The

contaminated diluted glutaraldehyde solution that was used to disinfect the

physical therapy devices may have been the source of the outbreak of M.

abscessus infection in 109 patients who underwent AP. PMID: 19694761

[PubMed - as supplied by publisher]

 

Evid Based Complement Alternat Med. 2009 Aug 17. [Epub ahead of print]

Changes of Blood Flow Volume in the Superior Mesenteric Artery and

Brachial Artery with Abdominal Thermal Stimulation. Takayama S, Seki T,

Watanabe M, Takashima S, Sugita N, Konno S, Takeda T, Arai H, Yambe

T, Yaegashi N, Yoshizawa M, Maruyama S, Nitta SI. Center for Asian

Traditional Medicine, Tohoku University Graduate School of Medicine, 1-1

Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan. t-seki.

In TCM, moxibustion is a local thermal therapy that is used for several

conditions. Quantifying the effects of moxibustion therapy has been difficult

because the treatment temperature depends on the physician's experience,

and the temperature distribution in the target area is not uniform. This

prospective observational study aims to quantify the effect of local thermal

stimulation to the abdomen. We developed a heat transfer control device

(HTCD) for local thermal stimulation. Twenty-four healthy subjects were

enrolled and they underwent abdominal thermal stimulation to the para-

umbilical region with the device for 20 min. Blood flow volume in the superior

mesenteric artery (SMA) and brachial artery (BA), the heart rate and the

blood pressure were measured at rest, 15 min after starting thermal

stimulation and 10, 20, 30 and 40 min after completing thermal stimulation.

Blood flow parameters were measured by high-resolution ultrasound. In the

SMA, blood flow volume was significantly increased during thermal

stimulation (p<.01), as well as at 10 min (p<.01) and 20 min (p<.05) after

stimulation. In the BA, blood flow volume decreased at 40 min after

stimulation (p<.01). In conclusion we could quantify the effect of local

thermal stimulation with an HTCD and high-resolution ultrasound. Thermal

stimulation of the para-umbilical region increased blood flow in the SMA 20

min after stimulation in healthy subjects. PMID: 19687193 [PubMed - as

supplied by publisher]

 

Evid Based Complement Alternat Med. 2009 Aug 20. [Epub ahead of print]

A Novel Uni-acupoint Electroacupuncture Stimulation Method for Pain

Relief. Niu C, Hao H, Lu J, Li L, Han Z, Tu Y. Director of Institute of Man-

Machine and Environmental Engineering, School of Aerospace, Room 803,

Main Building, Tsinghua University, Beijing 100084, China.

lilm. EAP has been demonstrated effective for pain relief

and treating other various diseases. However, the conventional way of EAP,

the bi-acupoint method, is not suitable for basis study of acupoint specificity.

Moreover, its operations are inconvenient and difficult to be persevered,

especially for long-term, continuous and even imperative treatments. These

disadvantages motivate designs of new EAP methods. We present a novel

uni-acupoint electrical stimulation method, which is applied at a single

acupoint and quite meets the needs of basis study and simpler clinical

application. Its pain relief effect has been evaluated by animal tests of

Wistar rats. During the experiments, rats were given 30 min 2/100 Hz uni-

and bi-acupoint EAP and their nociceptive thresholds before and after EAP

were attained by hot-plate test. The analgesic effect was defined as the

change of nociceptive threshold and used to evaluate the effectiveness of

uni-acupoint EAP for pain relief. The hot-plate test results indicated that

analgesic effect of uni-acupoint group was significantly higher than that of

the control group and there was no significant difference of analgesic effects

between uni- and bi- acupoint EAP. The results suggested that uni-acupoint

method was an effective EAP method and had comparable pain relief effect

with bi-acupoint method. PMID: 19696194 [PubMed - as supplied by

publisher]

 

Gastroenterol Nurs. 2009 Jul-Aug;32(4):243-55. Symptom management for

irritable bowel syndrome: a pilot randomized controlled trial of

acupuncture/moxibustion. Anastasi JK, McMahon DJ, Kim GH. Columbia

University School of Nursing, New York, NY 10032, USA.

jka8 AIM: To assess the effect of an individualized TCM AP

and moxibustion (AP-Mox) treatment on symptom control in patients with

irritable bowel syndrome (IBS) in a preliminary, randomized, sham/placebo-

controlled trial. 29 men and women with IBS were randomized to either

individualized AP-Mox (treatment group) or sham/placebo AP-Mox (control

group). All subjects were assessed by a diagnostic acupuncturist for a TCM

evaluation and individualized point prescription. Only those subjects

assigned to the experimental group received the individually prescribed

treatment. The diagnostic acupuncturist did not administer treatments and

was blind to treatment assignments. All subjects kept a symptom diary for

the duration of the study, enabling measurement of symptom frequency,

severity, and improvement. The Clinical Global Impression Scale was

administered preintervention to establish baseline severity and on

completion of the 4-week, eight-session treatment intervention. After 4

weeks of twice-weekly AP-Mox treatment, average daily abdominal

pain/discomfort improved whereas the control group showed minimal

reduction. This between-group difference adjusted for baseline difference

was statistically significant. The intestinal gas, bloating, and stool

consistency composite score showed a similar pattern of improvement. The

findings indicate that AP-Mox treatment shows promise in the area of

symptom management for IBS. PMID: 19696601 [PubMed - in process]

 

J Nerv Ment Dis. 2009 Aug;197(8):619-22. Electroacupuncture for refractory

obsessive-compulsive disorder: a pilot waitlist-controlled trial. Zhang ZJ,

Wang XY, Tan QR, Jin GX, Yao SM. School of CM, University of Hong

Kong, Hong Kong, China. zhangzj A large proportion of

obsessive-compulsive disorder (OCD) patients are refractory to

pharmacological and cognitive-behavioral therapy. The aim of this pilot,

waitlist-controlled trial was to evaluate the effectiveness of EAP as add-on

therapy for treatment-resistant OCD. Nineteen patients with treatment-

resistant OCD were assigned to EA treatment for 12 sessions (5 sessions

per week, n = 10) or waitlist for controls (n = 9) while continuing their

current

anti-OCD medications. The clinical outcomes were measured using the

Yale-Brown Obsessive-Compulsive Scale and the Clinical Global

Impression-Severity at baseline and end point. EAP additional treatment

produced significantly greater improvements at end point compared with the

waitlist group in reducing both Yale-Brown Obsessive-Compulsive Scale

(10.2 +/- 4.2 vs. 18.8 +/- 7.4, p = 0.004) and Clinical Global Impression-

Severity scores (3.0 +/- 1.1 vs. 4.4 +/- 1.1, p = 0.002). As an additional

therapy, EAP is effective in alleviating OCD symptoms of treatment-resistant

patients. A large-scale controlled study is warranted. Publication Types: *

Comparative Study * Controlled Clinical Trial * Research Support, Non-U.S.

Gov't PMID: 19684500 [PubMed - indexed for MEDLINE]

 

J Urol. 2009 Aug 18. [Epub ahead of print] Transcutaneous Electrical Nerve

Stimulation for Refractory Daytime Urinary Urge Incontinence. Hagstroem S,

Mahler B, Madsen B, Djurhuus JC, Rittig S. Institute of Clinical Medicine,

Aarhus University Hospital, Skejby, Aarhus, Denmark. PURPOSE: We

studied the effect of TENS in children with overactive bladder and treatment

refractory daytime urinary incontinence. MATERIALS AND METHODS: We

recruited 27 children 5 to 14 years old with daytime urge incontinence

refractory to timer assisted standard urotherapy and anticholinergics who

had normal urinalysis, and unremarkable urinary tract ultrasound and

physical examination. Study exclusion criteria were bladder underactivity,

lower urinary tract obstruction, ongoing defecation disorders, lower urinary

tract surgery and previous TENS. After a 2-week run-in of standard

urotherapy the children underwent natural fill ambulatory urodynamics to

confirm detrusor overactivity. Subsequently they were randomly allocated to

4 weeks of 2 hours of daily active or placebo TENS at S2-S3. The severity

of incontinence and urgency, and 48-hour bladder diaries were recorded

before randomization and during intervention week 4. Children withdrew

from anticholinergics throughout the study period. RESULTS: Two children

were excluded from randomization due to urodynamic signs of lower urinary

tract obstruction. After 4 weeks of intervention 8 children (61%) in the active

group showed a significant decrease in incontinence severity but this

occurred in only 2 (17%) in the sham treated group (p <0.05). The active

group had a significantly greater decrease in daily incontinence episodes

compared to the sham treated group (p <0.01). TENS did not alter maximal

and average voided volumes. CONCLUSIONS: Sacral TENS seems

superior to placebo for refractory daytime incontinence in children with

overactive bladder. This effect does not seem to be a consequence of

improved bladder reservoir function. PMID: 19695629 [PubMed - as

supplied by publisher]

 

Photomed Laser Surg. 2009 Aug;27(4):607-10. Effect of biostimulation on

wound healing in diabetic rats. Güngörmüs M, Akyol UK. Department of Oral

and Maxillofacial Surgery, Faculty of Dentistry, Ataturk University, Erzurum,

Turkey. gungormusm BACKGROUND AND OBJECTIVE:

Impaired wound healing is a complication of diabetes and is a serious

problem in clinical practice. AIM: To evaluate the effect of laser

biostimulation on wound healing in diabetic rats. MATERIAL AND

METHODS: 36 female Wistar rats weighting 250-300 g were used for this

study. Diabetes was chemically induced with streptozotocin. 18 nondiabetic

and 18 diabetic rats were included in the analysis. One incision was

performed on the dorsum of each nondiabetic rat and the wound served as

a control. Two parallel incisions were performed on the dorsum of each

diabetic rat. The laser treatments were started immediately after surgery

and were repeated on the second, fourth, sixth, and eighth days. A GaAlAs

laser was used with an 808 nm wavelength. One wound of each diabetic rat

received 10 J/cm(2) laser stimulation. RESULTS: Inflammation and re-

epithelialization were evaluated in all groups, and there was a significant

difference between the nondiabetic scalpel, diabetic scalpel, and diabetic

scalpel + biostimulation groups. CONCLUSIONS: Treatment with laser

biostimulation showed a beneficial effect on wound healing in diabetic rats. It

can be concluded that LLLT (808 nm laser at 10 J/cm(2)) can have a

beneficial effect on diabetic wound healing, when used at 2 d intervals over

5 d. Publication Types: * Research Support, Non-U.S. Gov't PMID:

19694508 [PubMed - in process]

 

Photomed Laser Surg. 2009 Aug;27(4):641-6. The effects of infrared low-

level laser therapy on healing of partial osteotomy of tibia in streptozotocin-

induced diabetic rats. Javadieh F, Bayat M, Abdi S, Mohsenifar Z, Razi S.

Anatomy Department, Medical Faculty, Shahid Beheshti University, MC,

Tehran, Iran. OBJECTIVE: The effects of LLLT on a bone defect model in

streptozotocin-induced diabetic (STZ-D) rats was examined.

BACKGROUND DATA: LLLT accelerates bone fracture repair in healthy

animals, but its effect in diabetic animals is unclear. METHODS: Twenty-

eight rats were divided into five groups: 1 (diabetes, no LLLT), 2 (diabetes,

LLLT high dose), 3 (diabetes, LLLT low dose), 4 (no diabetes, no LLLT), and

5 (no diabetes, LLLT low dose) Diabetes was induced by a single injection

of STZ in rats of groups 1, 2, and 3. A bone defect was made in the right

tibia of rats in all groups. The defect in groups 2, 3, and 5 was treated with

LLLT (890 nm, 70 W, 3000 Hz, circular beam shape, and 1 cm(2) spot size).

Doses of 23.3 J/cm(2) (530 s) for group 2 and 11.6 J/cm(2) (265 s) for

groups 3 and 5 were applied three times a week. The right tibias were

collected 42 days after surgery and subjected to three-point bending test on

a material testing machine (MTM) until fracture occurred. Data was

automatically recorded on the MTM formed the load-deformation curve.

RESULTS: Mann-Whitney test showed that LLLT with 11.6 J/cm(2)

significantly increased bending stiffness and maximum force in diabetic rats

compared with group 1 (both p = 0.041). CONCLUSION: LLLT in an

experimental diabetic model enhanced bone repair with a higher bending

stiffness and maximum force compared to the control group. Publication

Types: * Research Support, Non-U.S. Gov't PMID: 19694509 [PubMed - in

process]

 

Zhen Ci Yan Jiu. 2009 Apr;34(2):101-5. [Effect of electroacupuncture on

astrocytes in the marginal zone of cerebral ischemia locus in rats] [Article in

Chinese] Luo Y, Xu NG, Yi W, Du YX. College of of AP-Moxibustion and

Tuina, Guangzhou University of CM, Guangzhou 510006, China.

OBJECTIVE: To observe the effect of EAP on changes of ultrastructure and

proliferation of astrocytes in the marginal zone of the cerebral ischemia

locus in rats at different time courses so as to explore its underlying

mechanism in the treatment of cerebral ischemia (CI). METHODS: Ninety

Wistar rats were randomized into sham operation (sham), model and EAP

groups which were further divided into 1 h, 1 d, 3 d, 7 d, and 21 d

subgroups, with 6 cases in each. CI model was established by occlusion of

the middle cerebral artery with heat-coagulation. EAP (4/20 Hz, 2-3 V, 1-3

mA) was applied to GV20 and GV14 for 30 min once daily. The

ultrastructure changes of astrocytes were observed by using transmission

electronic microscope, and glial fibrillary acidic protein (GFAP) expression of

astrocytes was displayed by using immuno-fluorescent dyeing and observed

under laser confocal scanning microscope (LCSM). RESULTS: Following

CI, the astrocytes were swelling in structure and increased in number in CI

model group, while compared with model group, the degree of swelling of

astrocytes was decreased obviously in EAP group. The mean fluorescence

intensity values of GFAP on day 1, day 3, day 7 and day 21 post-modeling in

model group increased significantly in comparison with sham group (p<.01),

while those of GFAP from day 1 to day 21 post-modeling in EAP group were

significantly lower than those in model group (p<.01, p<.05), suggesting an

inhibitory effect of EAP on CI-induced upregulation of GFAP expression.

CONCLUSION: EAP of GV20 and GV14 can relieve CI-induced

ultrastructural injury of astrocytes in the rat, which is closely with its

effect in

inhibiting CI-induced overexpression of GFAP in astrocytes of the ischemic

brain tissue. Publication Types: * English Abstract PMID: 19685723

[PubMed - in process]

 

Zhen Ci Yan Jiu. 2009 Apr;34(2):106-9. [Effect of " Xiusanzhen " on learning-

memory ability and hippocampal somatostatin and arginine vesopressin

contents in vascular dementia rats] [Article in Chinese] Niu WM, Liu ZB,

Yang XH, Niu XM, Wang Y. Department of AP-Moxibustion and

Cerebropathy, Affiliated Hospital of Shaanxi College of CM, Xianyang

712083, China. niuwenmin6 OBJECTIVE: To observe the effect

of EAP of " Xiusanzhen " [bilateral LI 20 + Yintang] on learning-memory ability

and hippocampal somatostatin (SS) and arginine vasopressin (AVP)

contents in vascular dementia (VD) rats. METHODS: Forty SD rats were

randomly divided into control, VD model, VD plus olfactory bulb lesion (OBL,

destroyed by electro-coagulation) and EAP groups, with 10 cases in each.

VD model was established by 4-vessel occlusion. Morris maze tests were

conducted for evaluating the rats' learning and memory ability. EAP (1-3 mA,

80/100 Hz) was applied to bilateral LI 20 and GV 29 in VD + OBL and EAP

groups for 10 min, once daily (except Saturdays and Sundays) for 6 weeks.

The contents of SS and AVP in hippocampus tissue were measured by

radioimmunoassay. RESULTS: In comparison with control group, the

average escape latency (AEL) prolonged significantly and the target-

platform crossing times (TPCT) decreased remarkably in VD model group

(p<.01). In comparison with VD model group, the AEL was shortened and

TPCT increased remarkably in EAP group (p<.01). No significant

differences were found between VD model and VD + OBL groups in the AEL

and the TPCT (P > 0.05). Hippocampal SS and AVP contents in VD model

group were significantly lower than those in control group (p<.05), while

those in EAP group were markedly higher than those in VD model group

(p<.05). No significant differences were found between VD model and VD +

OBL groups in SS and AVP contents (P > 0.05). CONCLUSION: EAP of

" Xiusanzhen " can improve VD rats' learning-memory ability, which may be

related to its effects in raising hippocampal SS and AVP contents and to the

intact olfactory pathway. Publication Types: * English Abstract PMID:

19685724 [PubMed - in process]

 

Zhen Ci Yan Jiu. 2009 Apr;34(2):110-3. [Effect of electroacupuncture on the

permeability of blood-brain barrier for nerve growth factor and its relevance

to PKC pathway in cerebral ischemia rats] [Article in Chinese] Lin XM, Tan

KP, Zhang AJ, He LH. Zhejiang University of CM, Hangzhou 310053, China.

linxianming66 OBJECTIVE: To observe the effect of EAP of

GV20 and GV15 on the permeability of blood-brain barrier for exogenous

nerve growth factor (NGF) and its relevance to PKC pathway in cerebral

ischemia (CI) rats. METHODS: Forty-eight SD rats were randomized into

sham-operation (sham), model, NGF, EAP, NGF + EAP, and NGF + H7 +

EAP groups. CI model was established by repeated occlusion of the bilateral

carotid arteries and reperfusion. NGF (10 microg/kg) was administrated by

intravenous injection (vena caudalis); while H 7 [1-(5-isoquinolinesulfonyl)-2-

mehtylpoperazine, an inhibitor of protein kinase C (PKC), 1 mg/kg] was

given by intraperitoneal injection. EAP (100 Hz, 2 mA) was applied to GV20

and GV15 for 20 min. NGF content in the brain tissue was assayed by

enzyme-labeled immunosorbent assay (ELISA). RESULTS: In comparison

with sham group, cerebral NGF content had no apparent change in model

group (P > 0.05). Comparison among the abovementioned 6 groups showed

that cerebral NGF level in NGF + EAP group was significantly higher than

those in sham, model, EAP and NGF groups (p<.01). No significant

differences were found among sham, model, NGF, EAP and NGF+ H7 +

EAP groups and between NGF + EAP and NGF + H7 + EAP groups in

cerebral NGF contents (P > 0.05). CONCLUSION: EAP of GV20 and GV15

can raise the permeability of blood-brain barrier for NGF to increase its level

in the cerebral tissue in CI rats, favoring the regeneration and repair of

nerves, which has no clear relevance to PKC pathway. Publication Types: *

English Abstract PMID: 19685725 [PubMed - in process]

 

Zhen Ci Yan Jiu. 2009 Apr;34(2):114-9. [Effect of electroacupuncture on

plasma endogenous endothelial progenitor cell counts in cerebral ischemia-

reperfusion rats] [Article in Chinese] Cai SX, Yu WJ, Zhang L, Wang XZ,

Zhao Y, Chen SJ. College of bioengineering, Chongqing University,

Chongqing 400044, China. fish-505 OBJECTIVE: To observe the

effect of EAP on peripheral blood endothelial progenitor cell (EPC) counts,

vascular endothelial growth factor (VEGF) level and total nitric oxide

synthase (TNOS) and inducible nitric oxide synthase (iNOS) activity in

cerebral ischemia-reperfusion injury (CI/RI) rats. METHODS: A total of 72

male rats were randomly and evenly assigned to normal control, sham-

operation (sham), model and EAP groups which were further divided into 24

h, 48 h and 72 h subgroups, with 6 cases in each. Acute focal cerebral

ischemia model was established by occlusion of the middle cerebral artery

(MCAO, 120 min) and reperfusion. EAP (2/15 Hz, 1 mA) was applied to LI11

and ST36 for 30 min, once daily. Peripheral blood was collected from

abdominal aorta for detecting EPC count by using flow cytometry, serum

VEGF level by using enzyme-linked immunosorbent assay (ELISA), and

serum TNOS and iNOS activity by spectrophotometry, respectively.

RESULTS: Compared with the corresponding normal control subgroups,

blood EPC counts, serum TNOS and INOS activity and serum VEGF

content at 24 h, INOS activity and VEGF level at 48 h, and EPCs and INOS

at 72 h in model subgroups all increased significantly (p<.01, p<.05). In

comparison with the corresponding model subgroups, EPC count at 24 h

and 72 h, and TNOS activity at 24 h in EAP subgroups decreased

considerably (p<.01, p<.05); while EPC and VEGF levels at 48 h in EAP

subgroup increased evidently (p<.05, p<.01). No significant differences were

found among normal, sham, model and EAP subgroups in serum TNOS

activity at 48 h and 72 h (P > 0.05). CONCLUSION: EAP of LI11 and ST36

can suppress CI/ RI induced increase of blood EPC count and serum TNOS

activity, and upregulate serum VEGF level, which may contribute to its effect

in relieving CI/RI. Publication Types: * English Abstract PMID: 19685726

[PubMed - in process]

 

Zhen Ci Yan Jiu. 2009 Apr;34(2):120-4. [Randomized controlled clinical

trials of acupuncture treatment of chronic fatigue syndrome] [Article in

Chinese] Wang JJ, Song YJ, Wu ZC, Chu XO, Wang QM, Wang XJ, Wei

LN, Meng H, Wang XH. Institute of AP-Moxibustion, China Academy of

Chinese Medical Sciences, Beijing 100700, China. wjj751

OBJECTIVE: To observe the effect of AP on the fatigue degree in patients

with chronic fatigue syndrome (CFS). METHODS: Seventy CFS patients

were equally randomized into control and treatment groups according to

randomized block design. AP was applied to GV20, CV17, CV12, etc., for

patients in treatment group, and to non-acupoints (2 cm respectively to the

abovementioned acupoints) for those in control group. The treatment was

given once every other day, 14 times altogether. The fatigue degree and the

therapeutic effect were assessed by Chalder's fatigue scale (FS).

RESULTS: A total of 64 cases (32/group) were finished in this study. After

the treatment, the physical FS (5.0 +/- 2.4 vs 6.8 +/- 1.5), mental FS (1.8 +/-

1.8 vs 3.1 +/- 1.5) and the total FS (6.8 +/- 3.8 vs 9.9 +/- 2.5) in treatment

group, physical FS (5.0 +/- 2.5 vs 6.4 +/- 1.5) and the total FS (7.5 +/- 3.4 vs

9.6 +/- 2.8) in control group decreased significantly compared with pre-

treatment (p<.01, p<.05). There was no marked change in mental FS (2.5

+/- 11.6 vs 3.2 +/- 11.6) in control group after the treatment (P > 0.05).

Comparison between two groups showed no significant differences in the 3

indexes (P > 0.05). CONCLUSION: AP can relieve CFS patients' physical

and mental fatigue and the therapeutic effect of AP of acupoints is relatively

better than that of non-acupoints in reducing mental fatigue. Publication

Types: * English Abstract PMID: 19685727 [PubMed - in process]

 

Zhen Ci Yan Jiu. 2009 Apr;34(2):125-7, 135. [Observation on the

therapeutic effect of electroacupuncture of Jiaji (EX-B 2) plus regional

encircled needling for herpes zoster] [Article in Chinese] Li X, Zhang HX,

Huang GF, Feng YF, Zou R. School of AP-Moxibustion. Hubei College of

CM, Wuhan 430061, China. Lee-xuan OBJECTIVE: To observe

the clinical therapeutic effect of EAP of Jiaji (EX-B 2) plus focus-encircled

needling for promoting the crust formation of herpes zoster and analgesia.

METHODS: Eighty cases of herpes zoster patients were equally randomized

into EAP group [treated with EAP of Ashi-point, Jiaji (EX-B 2), SJ06 and

SI03, once daily for 10 times] and medication group (treated with valaciclovir

hydrochloride 300 mg/time, b. i. d. and vitamin B1 10 mg/time, t.i.d., 10

days). The pain severity was evaluated by using visual analogous scale

(VAS) method. The time when the cutaneous scabbing area was equal or

over 50% was recorded. RESULTS: After the treatment, of the two 40 cases

in EAP and medication groups, 30 (75.0%) and 15 (37.5%) were cured, 7

(17.5%) and 12 (30.0%) improved, 3 (7.5%) and 13 (32.5%) failed, with the

total effective rates being 92.5% and 67.5%, respectively. The therapeutic

effect of EAP was significantly superior to that of medication (p<.01). VAS

scores of both groups reduced significantly (p<.01). Both the VAS score and

the crust formation time of EAP group were significantly lower than those of

medication group (p<.01). CONCLUSION: EAP of Jiaji (EX-B 2) in

combination with focus-encircled needling is effective in facilitating the crust

formation and pain relief in the treatment of herpes zoster, and the effect of

AP is superior to that of medication. Publication Types: * English Abstract

PMID: 19685728 [PubMed - in process]

 

Zhen Ci Yan Jiu. 2009 Apr;34(2):128-31. [Effect of alternative administration

of scalp-acupuncture, body-acupuncture and abdominal-acupuncture on the

upper-limb dyscinesia in patients with stroke] [Article in Chinese] Zhou W,

Liu H, Wang LP, Xu ZG, Feng YW, Lv H, Xie Y, Guo J, Liu M, Liu Y. The

Stroke Ward, Huguosi CM Hospital Affiliated to Beijing University of CM,

Beijing 100035, China. dzhouwei OBJECTIVE: To observe the

effect of combined treatment of apoplectic upper-limb dyscinesia with scalp-

AP, body-AP and abdominal-AP in stroke patients. METHODS: A total of

222 stroke patients were randomized into treatment group (n = 133) and

control group (n = 89) according to the random number table method. For

patients of treatment group, scalp-point used was Motor Area (MS 6); body

acupoints were LI04, LI11, LI10, etc; and abdominal acupoints CV12, CV06,

etc. For patients in control group, only the same body acupoints were used.

AP treatment was given once daily for 5 weeks. The therapeutic effects

were evaluated by Fugl-Meyer motor function assessment (FMA) and

Barthel-index (BI) scores. RESULTS: In comparison with pre-treatment,

FMA score and BI score increased significantly 5 weeks, 1 and 3 months in

treatment group, 1 and 3 months in control group (p<.01). Comparison

between two groups showed that both FMA score and BI score of treatment

group were markedly higher than those of control group 5 weeks, 1 and 3

months after the treatment (p<.01). CONCLUSION: Alternative

administration of scalp-AP, body-AP and abdominal AP can effectively

improve stroke patients' upper-limb motor function, and its effect is

obviously better than that of simple body AP. Publication Types: * English

Abstract PMID: 19685729 [PubMed - in process]

 

Zhen Ci Yan Jiu. 2009 Apr;34(2):89-92, 119. [influence of

electroacupuncture on hepatic cytochrome P450 1 A 1 expression and lipid

peroxidation in nonalcoholic fatty liver rats] [Article in Chinese] Feng WQ,

Liu QY, Zeng ZH, Zhou LS. School of CM, Chongqing Medical University,

Chongqing 400050, China. moonly1981 OBJECTIVE: To study

the effect of EAP on liver cytochrome P450 1 A 1 immunoactivity,

superoxide dismutase (SOD) and malondialdehyde (MDA) contents in

nonalcoholic fatty liver disease (NAFLD) rats. METHODS: 30 male SD rats

were randomized into normal control (n = 10), model (n = 10) and EAP (n =

10) groups. NAFLD model was established by feeding the animal with high-

fat forage for 8 weeks. EAP (1.6-2 Hz, 1-4 mA) was applied to bilateral

ST36, ST40, SP06 and LV03 for 15 min, once daily for 4 weeks. Then the

rats anesthetized with ether were killed for collecting liver tissue. Following

homogenate and centrifugalization of the partial liver tissue, the supernatant

was collected for assaying superoxide dismutase (SOD) and

malondialdehyde (MDA) contents by xanthinoxidase chromometry and thio-

malonylurea chromometry respectively. The other partial liver tissue

samples were fixed in 10% formalin, followed by paraffin imbedding and

sectioning (4 microm), and staining with streptavidin-perosidase methods

respectively for displaying hepatic pathological changes and cytochrom

P450 1 A 1 immunoreaction. RESULTS: Compared with control group,

hepatic SOD content of model group was significantly lower (p<.05), and

MDA level and cytochrome P450 1 A 1 (CYP 1 A 1) integrated optic density

(IOD) value were obviously higher in model group (p<.05). In comparison

with model group, liver SOD level of EAP group increased considerably

(p<.05), while MDA level and CYP 1 A 1 IOD of EAP group decreased

evidently in EAP group (p<.05). CONCLUSION: EAP can effectively reduce

lipid peroxidation and up-regulate CYP 1 A 1 expression in nonalcoholic fatty

liver tissue, which may contribute to its effect in improving fatty liver.

Publication Types: * English Abstract PMID: 19685720 [PubMed - in

process]

 

Zhen Ci Yan Jiu. 2009 Apr;34(2):93-6. [Effect of electroacupuncture at

" Zusanli " (ST36) and " Sanyinjiao " (SP06) on collagen-induced arthritis and

secretory function of knee-joint synoviocytes in rats] [Article in Chinese]

Fang JQ, Shao XM, Ma GZ. 3rd Clinical Medical College, Zhejiang Chinese

Medical University, Hangzhou 310053, China. fangjianqiao

OBJECTIVE: To observe the effect of EAP of ST36 and SP06 on collagen-

induced arthritis (CIA) and its underlying mechanism in regulating the

secretory function of knee-joint synovial cells in CIA rats. METHODS: Thirty-

six Wistar rats were equally randomized into control, model and EAP

groups. CIA model (rheumatoid arthritis) was duplicated by intradermal

injection of Bovine type II collagen into the back of the anesthetized rats.

EAP (2 Hz, 2 mA) was applied to ST36 and SP06 for 30 min, once a day for

30 days. The paw volume was measured by using a Plethysmometer and

hot water tail-flick tests (50 degrees C) were conducted for detecting the

rats' pain threshold (PT) before and after the treatment. The contents of

PGE2, IL-1beta and TNF-alpha in supernatant of the cultured joint

synoviocytes were detected by enzyme linked immunosorbent assay

(ELISA). RESULTS: In comparison with control group, the swelled paw

volume, the declined PT, PGE2, TNF-alpha and IL-1beta contents in knee-

joint synoviocyte supernatant were significantly higher in model group

(p<.05). Compared with model group, PT increased obviously (p<.05); paw

volume, supernatant PGE2, TNF-alpha and IL-1beta contents decreased

obviously (p<.05) in EAP group. CONCLUSION: EAP of ST36 and SP06

has a pronounced therapeutic effect in relieving knee joint pain and

inflammation in CIA rats, which may be related to its effect in regulating the

secretory function of the knee-joint synoviocytes. Publication Types: *

English Abstract PMID: 19685721 [PubMed - in process]

 

Zhen Ci Yan Jiu. 2009 Apr;34(2):97-100. [influence of acupuncture and

moxibustion on conditional position preference and prefrontal cortical

ultrastructure in heroin re-addicted rats] [Article in Chinese] Zhang RJ, Song

XG, Cai XH. Department of Anatomy, Anhui College of CM, Hefei 230038,

China. zrj0001 OBJECTIVE: To observe the effect of AP

and moxibustion on the conditional position preference (CPP) and prefrontal

cortical ultrastructure in heroin re-addicted rats. METHODS: Thirty-two

Wistar rats were randomly divided into normal, model, medication and AP-

Moxibustion (AP-Mox) groups, with 8 cases in each. Re-addiction model

was established by repeated intramuscular injection of heroin into the

hindlimbs. Rats of medication group were treated with intragastric

administration of Methadone during detoxification. For rats in AP-Mox group,

AP needle was inserted into GV20 and moxibustion treatment was used to

bilateral BL23 for 30 min during detoxification. Rats in normal group were

given with intramuscular injection of normal saline during addiction. CPP

tests were conducted once daily in a spatial place preference box for 8 days.

On the 39th day of the experiment, the rats under anesthesia were killed for

sampling the prefrontal cortex (PFC) tissue on an ice plate, then, the

ultrastructure of the neurons was observed by using a transmission electron

microscope. RESULTS: After modeling, the rats' staying duration in the

dark-box was shortened obviously (p<.01). After the treatment, the staying

duration in dark-box in AP-Mox group was significantly longer than that in

model and medication groups (p<.01). Compared with normal control group,

electron-microscopic results indicated that in PFC tissues of model and

medication groups, vacuoles and edema of cytoplasm at different degrees,

enlargement of the rough endoplasmic reticulum (REPR), vacuoles or

disappearance of mitochondria, reduction of ribosome in number, and

widening of the nuclear intermembrance interstice were seen. While in AP-

Mox group, the number of mitochondria and ribosome increased slightly, the

mitochondrial cristae was clear, the number of REPR increased relatively

but dilated slightly, and the intermembrance space was basically normal.

CONCLUSION: AP-Mox can improve heroin re-addicted rats' conditional

position preference and has a protection effect on the cerebral cortical

neurons. disappearance of mitochondria, reduction of ribosome in number,

and widening of the nuclear intermembrance interstice were seen. While in

AP-Mox group, the number of mitochondria and ribosome increased slightly,

the mitochondrial cristae was clear, the number of REPR increased

relatively but dilated slightly, and the intermembrance space was basically

normal. CONCLUSION: AP-Mox can improve heroin re-addicted rats'

conditional position preference and has a protection effect on the cerebral

cortical neurons. Publication Types: * English Abstract PMID: 19685722

[PubMed - in process]

 

Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2009 Aug;21(8):485-7. [The effects

of electro-acupuncturing at Zusanli point on intestinal proinflammatory

factors, diamine oxidase and tissue water content in rats with sepsis.]

[Article in Chinese] Hu S, Zhang LJ, Bai HY, Bao CM. Laboratory of Shock

and Multiple Organ Dysfunction, Burns Institute, First Hospital Affiliated to

the PLA General Hospital, Beijing 100048, China. OBJECTIVE: To

investigate the protective effect of EAP at ST36 point on sepsis induced

ischemic and oxygen free radical intestinal injury in rats with sepsis.

METHODS: Thirty-two male Wistar rats were used to reproduce sepsis by

cecal ligation and puncture (CLP), and they were randomly divided into four

groups (each n=8): CLP+EAP (CLP/EAP), CLP+sham EAP (CLP/SEAP),

vagotomy+CLP+SEAP (VA/CLP/SEAP) and vagotomy+CLP+EAP

(VA/CLP/EAP). EAP was given to ST36 with constant voltage (2-100 Hz,2

mA for 30 minutes) immediately after CLP surgery. Abdominal vagotomy

was performed in rats in VA/CL/SEAP and VA/CLP/SEAP groups. Six hours

after CLP, the mucosal blood flow of jejunum (JMBF) was measured.

Animals were sacrificed after 6 hours and specimens of jejunum were

harvested for evaluation of malondialdehyde (MDA), xanthine oxidase

(XOD), diamine oxidase (DAO) and assessment of the water content

(WCR). RESULTS: JMBF and the activity of DAO of CLP/EAP group were

markedly higher, and the levels of XOD, MDA and WCR in jejunal tissue

were obviously lower than those of CLP/SEAP group (all P<0.05). The levels

of JMBF and DAO of the VA/CLP/SEAP group and VA/CLP/EAP group were

significantly lower, and XOD, MDA and WCR obviously higher than those of

the CLP/EAP group ( all P<0.05 ). There were no statistically differences in

all above measurements between the VA/CLP/EAP group and the

VA/CLP/SEAP group (all P>0.05). CONCLUSION: The results indicate that

EAP at ST36 point obviously increased JMBF and DAO, and alleviated

tissue edema and insult of intestinal mucosa. Vagotomy could weaken or

eliminate the effects of EAP. It is suggested that cholinergic anti-

inflammatory pathway is one of the main mechanisms of intestinal protective

effect of EAP at ST36. Publication Types: * English Abstract PMID:

19695173 [PubMed - in process]

 

Zhongguo Zhen Jiu. 2009 Jun;29(6):459-62. [Clinical study on acupuncture

combined with medication in restoration of gastrointestinal functions for

postoperative patients with gastric cancer] [Article in Chinese] Yin SH, Du

YQ, Liu B. TCM College, Xinjiang Medical University, Urumqi 830054,

China. OBJECTIVE: To observe clinical therapeutic effects of AP combined

with medication in restoration of gastrointestinal functions for postoperative

patients with gastric cancer. METHODS: According to the sequence of their

operations, 90 patients undergoing radical surgeries for gastric cancer were

divided randomly into 3 groups: a control group treated conventionally after

their surgeries (group CONT, 30 cases), a CM group treated by Simo Tang

administered by way of a nutrient canal in addition to the conventional

treatment (group CM, 30 cases), and an AP plus CM group treated by

warming needling in addition to those given in the CM group (group AP+CM,

30 cases). Therapeutic effects were estimated 10 days after their

operations. RESULTS: The time for restoration of gastrointestinal functions

was obviously shortened, and the problems of poor appetite and difficulty in

defecation were more markedly improved in group AP+CM than those in

both group CONT and group CM (p<.01, p<.05). Ten days after operations,

the number of patients with normal lymphocytes and normal percentage rate

of lymphocytes to neutrophile granulocytes was obviously more in group

AP+CM than those in both group CONT and group CM (p<.01, p<.05).

CONCLUSION: AP combined with CM is favorable in accelerating early air

flatus and defecation, improving clinical symptoms, as well as in bi-

directional regulating peripheral white blood cells. Publication Types: *

English Abstract * Randomized Controlled Trial PMID: 19563193 [PubMed -

indexed for MEDLINE]

 

Zhongguo Zhen Jiu. 2009 Jun;29(6):501-3. [Research on Tuina treatment

for postpartum hypolactation] [Article in Chinese] Zheng JJ, Lu P, Zhao Y.

College of AP and Massage, Shanghai University of TCM, Shanghai

201203, China. In this paper, the TCM typing of postpartum hypolactation is

introduced and the manipulation and duration of Tuina treatment for

postpartum hypolactation are summarized, and the effectiveness index used

in Tuina treatment is proposed. It is held that the Tuina therapy will be widely

used for treatment of the postpartum hypolactation, and the convenient and

effective Tuina manipulation will promote the development of postpartum

nursing and will be used in gynecology department and enlarge the

therapeutic range of the Tuina therapy. Publication Types: * English Abstract

PMID: 19563202 [PubMed - indexed for MEDLINE]

 

Zhongguo Zhen Jiu. 2009 Jun;29(6):508-9. [standardized manipulations of

sharp hooked needling for treating migraine and investigation on its

mechanisms] [Article in Chinese] Jin CN, Zhang TS, Guan F, Ji LX, Li L, Li

XH, Hao SF, Yuan Y. AP and Moxibustion Institute of Shanxi Province,

Taiyuan 030006, China. nizi010501 A comparison of

recognition to migraine and treatment methods for it was made between

TCM and western medicine in this paper. Emphasis was made on

standardized manipulation processes and techniques of sharp hooked

needling for treating the disease, based on both the organic conception of

the human body, the theory held by TCM, and on the principle of treatment

according to pathogenesis obtained through differentiation of symptoms and

signs. The necessary preparation before operations, methods for its

application and announcements in the standardized manipulations of sharp

hooked needling were all explained in detail. Based on its needling, pricking,

dissecting and relaxing effects, the mechanisms of sharp hooked needling

in treating the disease were investigated. It is concluded that sharp hooked

needling is very effective in treating migraine. Publication Types: * English

Abstract PMID: 19563204 [PubMed - indexed for MEDLINE]

 

Best regards,