Guest guest Posted September 11, 2009 Report Share Posted September 11, 2009 Eric and All: My comments about the Lei Gong Teng article were not intended as a commentary regarding its toxicity or use. I was trying to point out some weaknesses in this particular study, that's all. Not a weakness with respect to evaluating it as an herb for use in Chinese herbology, but a weakness for evaluating its use in western medicine, or for anything at all really. Some studies are better than others, and this one was weak. That being said, Eric introduces some interesting issues in his comments I would like to respond to. I agree that the more toxic, alkaloid-containing herbs are more comparable to drugs in their action, than the herbs of lesser toxicity. I do not agree with his implication that the distinction between the actions of drug and herb, natural vs. synthetic is superfluous. I also do not agree that there is no room for dogma in medicine. I think medicine is full of dogma/doctrine. That's what it is. I think we need to look at these precepts carefully, and evaluate which doctrine serves best in which situation, as well as to what extent and how they might be combined successfully vs. unsuccessfuly. Of course I agree that our ultimate objective is about helping people. I do not believe any medicine has the answers for every illness or ever will. That is why I am supportive of a pluralistic medical community. I have great respect for western medicine. It is not TCM that is trying to claim a hegemony on medical truth and practice. While diversified disciplines can be practiced in a complementary fashion in an integrative fashion, this describes an event or a delivery system; it is not a system of medicine rooted in guiding precepts. TCM is a system of medicine. Ayurveda is a system of medicine. Homeopathy is a system of medicine. CAM is not a system of medicine. " Integrative medicine " is not a system of medicine. These are newly created, artificial constructs that erase not only the validity, but the very existence, of the identifying precepts and essential concepts of discrete medical systems. It begins with the " rectification of names " . best, ________________________________ smilinglotus <smilinglotus Wednesday, September 9, 2009 5:12:05 PM Re: Lei gong teng , <moringa123@ ...> wrote: > This is a drug-type, not crude extract, of Lei Gong Teng being used, but the details of its preparation are conspicuously missing from the monograph. Lei Gong Teng is, by all accounts, a highly effective medicinal for the treatment of RA. However, as others have mentioned, it poses a risk of severe side-effects and potential toxicity. It suppresses the immune system and requires monitoring of liver and kidney function, so it is only suitable for use in integrative settings and it should only be used in extracts that have precise, known levels of constituents. I agree that it is important for studies to state the details of preparations. Is it a full-spectrum, water-based extract, a fractional isolate, an ethanol extract? What species of plant was used and how was it authenticated (traditional quality discernment by a qualified expert, TLC, HPLC, etc)? What growing region did the herbs used in the study come from? All of these factors are extremely important for a rigorous study of herbal medicine products. That said, Lei Gong Teng is exactly the type of herb that may be more useful as a " drug " product, because it requires relatively precise dosing, consistent and transparently stated levels of active constituents, and lab testing of the patient to monitor toxicity. Think about something like datura (yang jin hua). Datura is one of the oldest medicines in the world, it has well-characterized pharmacological effects, but its active constituents are toxic and highly variable in the plant itself. Its constituents, such as atropine and scopolamine, have been used extensively in medicine and they are much safer than the whole herb because their dosage can be precisely determined. The whole herb should still be available for use, of course, but very few educated practitioners would prefer to use the crude herb instead of an extract with consistent constituent levels. I'm not trying to say that Lei Gong Teng should be made into a drug and denied access to herbalists. But I think that highly toxic items like Lei Gong Teng and Yang Jin Hua may offer significant benefit to humanity as drugs. Plants and drugs are intimately related. There are many examples where a pure drug fails to perform as well as the whole herb (ginseng is a good example). But other times, the pure drug may be more useful than the whole herb (as in the case of datura). Extreme feelings about natural vs. synthetic or " herb vs. drug " (whatever that means) don't really serve us well in the field of medicine. Medicine is about helping people, it is not about dogma. And let's face it, our suppliers rarely tell us the concentration ratio of simple things like mint (bo he) in the products that we use, how can we use dose-dependent, highly toxic substances like Lei Gong Teng or Yang Jin Hua without knowing the potency of the extracts on the market? Yes, I'd like to see more transparency in the herbal authentication and extraction information in studies, but I'd also like to see more transparency in the products we use in TCM. Eric Brand Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 12, 2009 Report Share Posted September 12, 2009 , wrote: > I do not agree with his implication that the distinction between the actions of drug and herb, natural vs. synthetic is superfluous. I don't think that the distinction between drugs and herbs, or natural vs. synthetic products is superfluous. There are important differences between natural products and pure drugs, and like many people on this list, I deeply value the complexity of natural products. For example, substances like ginseng cannot be duplicated by synthetic alternatives or fractional isolates. Different ginsenosides have distinct pharmacological properties, but only whole ginseng has exceptionally balanced and complex effects. None of the fractional isolates offer the benefits of the whole herb. I am personally inclined towards whole plant products. In many instances, the complex chemistry found in nature is superior to pure drugs. Nonetheless, many people in the alternative medicine community think that pure drugs are poison and organic substances are benign, and I think this viewpoint is overly simplistic. For example, strychnine is a completely natural substance (found in ma qian zi) but it is highly poisonous. By contrast, a drug like piracetam is remarkably benign even though it has no natural source. Furthermore, our knowledge of what is " natural " vs. " synthetic " is constantly changing. For example, amphetamine was thought to be a purely synthetic substance for decades, but then it was discovered as a natural constituent of a tree from Texas. The fact that amphetamine is a natural product that occurs in a whole plant does not make it benign. I'm an herbalist, I truly value whole plant products. I would never suggest that the distinction between herbs and drugs is superfluous. But I would also not make the assumption that everything that is man-made or isolated is bad and everything that is natural or full-spectrum is good. That is all I am trying to say. Eric Quote Link to comment Share on other sites More sharing options...
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