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Dear Dog Lovers,

 

 

 

Would you and your dog(s) like to come to a Dog March at UCSF? To sign up,

please email noanimalexperiment

 

 

 

Despite last year's " Day of the Dog " protest and many civilized attempts to

dialogue with UCSF's officials, UCSF is still determined to perform cruel heart

experiments on 750 to 800 dogs. They will implant pacemakers to make their

hearts beat extremely fast, and they will tear up a portion of their hearts.

Essentially, they will cause artificial heart failure from which to gather

artificial data to publish. The dogs will suffer in great pain for days to up

to six months, depending on the degree of problems and injuries caused. UCSF

has already acquired several dogs, now most likely already mutilated and

suffering at this very moment.

 

 

 

Why are they doing this when people already know that a dog's heart is very

different from a human heart anatomically and physiologically even down to the

cellular level? The reason is greed for the grant money financed by taxpayers.

The university keeps half of every grant awarded to the researchers. Also, they

think the public will never find out.

 

 

 

To get the media's attention, we need to hold the biggest Dog March ever. (Only

two dogs came to last year's " Day of the Dog " .) Please spread the news this

time as widely as possible and please ask everyone around you who has a

well-behaved dog to come take a walk with us.

 

 

 

We need at least 50 well-behaved dogs to commit for a couple of hours. The date

will be decided once this target is reached. It will have to be a weekday

because the media generally doesn't come on weekends. If you work on weekdays,

please see if you could take a day off. Anyone interested please email

noanimalexperiment

 

 

 

Thank you so much for your love of animals.

 

 

 

 

 

For those interested, below are more details on the two experiments by Dr.

Olgin:

 

--\

----------------------------

 

(1st Experiment)

 

550 dogs to be used in the next 3 years

 

 

 

Title: Remodeling in Atrial Fibrillation

 

 

 

Claimed Purpose: “To develop new therapies that may prevent cardiac arrhythmias

from leading to irreversible heart damage and chronic disease. "

 

 

 

Procedures: 150 dogs would be surgically implanted with one pacemaker. Another

150 dogs would be implanted with two pacemakers. Yet another 150 dogs would be

subjected to “mitral valve avulsion, " a surgical procedure that tears a portion

of the mitral valve of the dog's heart in order to cause “mitral regurgitation, "

or the blood to flow backwards. Another 100 dogs will be used as controls. The

450 dogs who undergo surgery are expected to survive 4 weeks to 6 months.

However, “the only animals that would survive for up to 6 months are the RAP

(rapid atrial pacing) dogs, and this is very rare. " The dogs “will be monitored

weekly, and daily if problems arise. " Problems may be “infection in pacemaker

pocket, signs of heart failure (i.e., ascites, lethargy), appearance of

continued pain such as crying, flinching from touch, limping or in any way

favoring incision area, or weight loss. " Some dogs will be given “experimental

drugs " ; i.e., Ace inhibitor, PAI-1 inhibitor, TFG-B antagonist,

and Pirfenidone. Thirty percent of the surgically impaired dogs are expected to

die before the project ends. All 550 dogs, if they survive, will eventually

undergo a terminal 8-hour-long electrophysiological study. While the dogs are

under general anesthesia, their chests are cut open. “To support the heart, a

pericardial cradle is made by suturing each corner of the cut pericardium to the

skin. Recordings of the heart's internal blood pressure, EKG, PQRST intervals,

and heart rates are taken for later analysis. Finally, the dogs will be

euthanized and their hearts removed for optical mapping, cellular

electrophysiology and histology analysis. "

 

 

 

--\

----------------------------

 

(2nd Experiment)

 

200 dogs to be used

 

 

 

Title: Effects of Congestive Heart Failure on Electrophysiology and Remodeling

 

 

 

Claimed Purpose: “To understand the mechanism by which heart failure causes

atrial fibrillation [arrhythmia]. "

 

 

 

Procedures: Experimenters plan to implant pacemakers in 160 dogs. 40 dogs will

be used as controls. Three to five days after surgery, the pacemakers will be

programmed to rapidly pace at 200 to 250 beats per minute for 2-6 weeks and/or

until the dogs show symptoms of heart failure. There is the potential for severe

pain as " adverse effects " include " abdominal bloating from heart failure,

pulmonary edema and coughing " and infection from the implantation of the

pacemakers. The dogs will receive analgesics “on an as needed basis. " Pain will

be assessed by “whether the dog flinches when touched, cries out when touched or

in any way favors the incision [from the surgery], or fails to eat and drink. "

It is planned for the dogs to live from 2-7 weeks after surgery. Five percent of

dogs are expected to die due to heart failure during the course of the

experiment. The dogs will undergo weekly EKG's “to assess the degree of heart

failure and/or mitral regurgitation. " All dogs, including

those in the control group, will be euthanized in the end and their hearts cut

out for “optical mapping, cellular electrophysiology and histology analysis " or

autoradiography.

 

 

 

 

 

Sincerely,

 

Michelle Tsai

 

(650) 619-9713

 

 

 

 

 

 

 

 

 

 

Celebrate 's 10th Birthday!

Netrospective: 100 Moments of the Web

 

 

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