Guest guest Posted July 16, 2007 Report Share Posted July 16, 2007 Grapefruit link to breast cancer Eating too much grapefruit could increase risks of breast cancerEating grapefruit every day could raise the risk of developing breast cancer by almost a third, US scientists say. A study of 50,000 post-menopausal women found eating just a quarter of a grapefruit daily raised the risk by up to 30%. The fruit is thought to boost levels of oestrogen - the hormone associated with a higher risk of the disease, the British Journal of Cancer reported. But the researchers and other experts said more research was still needed. This is an interesting study, but is simply a piece of the jigsaw that will eventually help us to understand how our diets affect our health Dr Joanne Lunn The women had to fill in questionnaires saying how often they ate grapefruit and how big their portions were. Oestrogen important The researchers, at the universities of South California and Hawaii, found that women who ate one quarter of a grapefruit or more every day had a higher risk of breast cancer than those who did not eat the fruit at all. Previous studies have shown that a molecule called cytochrome P450 3A4 (CYP3A4) is involved in metabolising oestrogen hormones. And grapefruit may boost blood oestrogen levels by inhibiting this molecule, allowing the hormones to build up. The researchers found that in women who ate at least a quarter of a grapefruit daily, levels of oestrogen were higher. They said: "It is well established that oestrogen is associated with breast cancer risk. "Therefore, if grapefruit intake affects oestrogen metabolism leading to higher circulating levels, then it is biologically plausible that regular intake of grapefruit would increase a woman's risk of breast cancer." More research And they said this was the first time a commonly eaten food had been linked to an increased risk of breast cancer in older women. However, they warned that more research was needed to confirm the findings which may have been affected because they only took into account intake of the fruit, but not grapefruit juice. Breast cancer accounts for almost a third of all cancers in women, and previous lifestyle factors linked to the disease include drinking alcohol and being overweight. Dr Joanne Lunn, a nutrition scientist at the British Nutrition Foundation said: "This is an interesting study of a large group of post-menopausal women whose diet and health have been followed for many years. "However, this study is simply a piece of the jigsaw that will eventually help us to understand how our diets affect our health. "Although we are beginning to get a better awareness of how our diets can modify the risk of diseases such as cancer, we are still a long way from identifying particular foods that might specifically increase or decrease risk." However, she said that some dietary patterns are associated with a reduced risk of certain cancers and that a diet rich in a variety of different fruits and vegetables could help reduce the risk of heart disease and some cancers. Peter H Mail is the world's favourite email. Don't settle for less, sign up for your free account today. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 17, 2007 Report Share Posted July 17, 2007 I would like to know what other constants they considered in their research, before I believe this. Incidentally I don't eat grapefruits at all, but doubt the conclusions they have come to. Jo , Peter VV <swpgh01 wrote: > > Grapefruit link to breast cancer > > Eating too much grapefruit could increase risks of breast cancer > > Eating grapefruit every day could raise the risk of developing breast cancer by almost a third, US scientists say. A study of 50,000 post-menopausal women found eating just a quarter of a grapefruit daily raised the risk by up to 30%. The fruit is thought to boost levels of oestrogen - the hormone associated with a higher risk of the disease, the British Journal of Cancer reported. But the researchers and other experts said more research was still needed. This is an interesting study, but is simply a piece of the jigsaw that will eventually help us to understand how our diets affect our health > > > Dr Joanne Lunn > > The women had to fill in questionnaires saying how often they ate grapefruit and how big their portions were. Oestrogen important The researchers, at the universities of South California and Hawaii, found that women who ate one quarter of a grapefruit or more every day had a higher risk of breast cancer than those who did not eat the fruit at all. Previous studies have shown that a molecule called cytochrome P450 3A4 (CYP3A4) is involved in metabolising oestrogen hormones. And grapefruit may boost blood oestrogen levels by inhibiting this molecule, allowing the hormones to build up. The researchers found that in women who ate at least a quarter of a grapefruit daily, levels of oestrogen were higher. They said: " It is well established that oestrogen is associated with breast cancer risk. " Therefore, if grapefruit intake affects oestrogen metabolism leading to higher circulating levels, then it is biologically plausible that regular intake of grapefruit would > increase a woman's risk of breast cancer. " More research And they said this was the first time a commonly eaten food had been linked to an increased risk of breast cancer in older women. However, they warned that more research was needed to confirm the findings which may have been affected because they only took into account intake of the fruit, but not grapefruit juice. Breast cancer accounts for almost a third of all cancers in women, and previous lifestyle factors linked to the disease include drinking alcohol and being overweight. Dr Joanne Lunn, a nutrition scientist at the British Nutrition Foundation said: " This is an interesting study of a large group of post-menopausal women whose diet and health have been followed for many years. " However, this study is simply a piece of the jigsaw that will eventually help us to understand how our diets affect our health. " Although we are beginning to get a better awareness of how our diets can modify the risk of > diseases such as cancer, we are still a long way from identifying particular foods that might specifically increase or decrease risk. " However, she said that some dietary patterns are associated with a reduced risk of certain cancers and that a diet rich in a variety of different fruits and vegetables could help reduce the risk of heart disease and some cancers. > > > > Peter H > > > > > Mail is the world's favourite email. Don't settle for less, sign up for your freeaccount today. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 17, 2007 Report Share Posted July 17, 2007 Exactly! At first I thought, what if all the grapefruit eaters are eating sausage and bacon for breakfast, and eat grapefruit to balance the fat? I have some neighbors who were doing this for a while. Or perhaps the grapefruits had some pesticide residue that caused this effect. But then I realized the study posited a chemical pathway implicating grapefruit and also played loose with statistics. I'm not sure what the researchers mean by " higher risk " : do they mean that more women developed BC? Or that they assume the risk of developing it is higher because grapefruit inhibits cytochrome P450 3A4 (CYP3A4) and thus allows higher estrogen levels? Maybe what they measured was estrogen levels, which are correlated with higher risk of bc. Re statistics: the " up to 30 percent higher " has no meaning unless you know what it's based on. So if the risk is 1 percent, then grapefruit would make it 1.3 percent. If it's 15 percent, it goes to 22 percent. But the way it's written and the way it's often interpreted in the lay press is that the risk goes from 1 to 31 percent, or from 15 to 45 percent. Huge difference. I eat grapefruit only in the winter, as a fruit, a whole one at a time. At 7:00 AM +0000 7/17/07, heartwerk wrote: >I would like to know what other constants they considered in their >research, before I believe this. Incidentally I don't eat >grapefruits at all, but doubt the conclusions they have come to. > >Jo > > , Peter VV <swpgh01 wrote: >> >> Grapefruit link to breast cancer >> >> Eating too much grapefruit could increase risks of >breast cancer >> >> Eating grapefruit every day could raise the risk of developing >breast cancer by almost a third, US scientists say. A study of >50,000 post-menopausal women found eating just a quarter of a >grapefruit daily raised the risk by up to 30%. The fruit is thought >to boost levels of oestrogen - the hormone associated with a higher >risk of the disease, the British Journal of Cancer reported. But >the researchers and other experts said more research was still >needed. This is an interesting study, but is simply >a piece of the jigsaw that will eventually help us to understand how >our diets affect our health >> >> >> Dr Joanne Lunn >> >> The women had to fill in questionnaires saying how often they ate >grapefruit and how big their portions were. Oestrogen important >The researchers, at the universities of South California and Hawaii, >found that women who ate one quarter of a grapefruit or more every >day had a higher risk of breast cancer than those who did not eat the >fruit at all. Previous studies have shown that a molecule called >cytochrome P450 3A4 (CYP3A4) is involved in metabolising oestrogen >hormones. And grapefruit may boost blood oestrogen levels by >inhibiting this molecule, allowing the hormones to build up. The >researchers found that in women who ate at least a quarter of a >grapefruit daily, levels of oestrogen were higher. They said: " It >is well established that oestrogen is associated with breast cancer >risk. " Therefore, if grapefruit intake affects oestrogen metabolism >leading to higher circulating levels, then it is biologically >plausible that regular intake of grapefruit would >> increase a woman's risk of breast cancer. " More research And >they said this was the first time a commonly eaten food had been >linked to an increased risk of breast cancer in older women. >However, they warned that more research was needed to confirm the >findings which may have been affected because they only took into >account intake of the fruit, but not grapefruit juice. Breast >cancer accounts for almost a third of all cancers in women, and >previous lifestyle factors linked to the disease include drinking >alcohol and being overweight. Dr Joanne Lunn, a nutrition scientist >at the British Nutrition Foundation said: " This is an interesting >study of a large group of post-menopausal women whose diet and health >have been followed for many years. " However, this study is simply a >piece of the jigsaw that will eventually help us to understand how >our diets affect our health. " Although we are beginning to get a >better awareness of how our diets can modify the risk of >> diseases such as cancer, we are still a long way from identifying >particular foods that might specifically increase or decrease >risk. " However, she said that some dietary patterns are associated >with a reduced risk of certain cancers and that a diet rich in a >variety of different fruits and vegetables could help reduce the risk >of heart disease and some cancers. >> >> >> >> Peter H >> >> >> >> >> Mail is the world's favourite email. Don't settle for less, >sign up for your freeaccount today. >> > > > > >To send an email to - > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 17, 2007 Report Share Posted July 17, 2007 Yarrow, you sound brilliant! What do you do for a living? Tracy --- yarrow wrote: > Exactly! At first I thought, what if all the > grapefruit eaters are > eating sausage and bacon for breakfast, and eat > grapefruit to balance > the fat? I have some neighbors who were doing this > for a while. Or > perhaps the grapefruits had some pesticide residue > that caused this > effect. > > But then I realized the study posited a chemical > pathway implicating > grapefruit and also played loose with statistics. > I'm not sure what > the researchers mean by " higher risk " : do they mean > that more women > developed BC? Or that they assume the risk of > developing it is higher > because grapefruit inhibits cytochrome P450 3A4 > (CYP3A4) and thus > allows higher estrogen levels? Maybe what they > measured was estrogen > levels, which are correlated with higher risk of bc. > > Re statistics: the " up to 30 percent higher " has no > meaning unless > you know what it's based on. So if the risk is 1 > percent, then > grapefruit would make it 1.3 percent. If it's 15 > percent, it goes to > 22 percent. But the way it's written and the way > it's often > interpreted in the lay press is that the risk goes > from 1 to 31 > percent, or from 15 to 45 percent. Huge difference. > > I eat grapefruit only in the winter, as a fruit, a > whole one at a time. > > > At 7:00 AM +0000 7/17/07, heartwerk wrote: > >I would like to know what other constants they > considered in their > >research, before I believe this. Incidentally I > don't eat > >grapefruits at all, but doubt the conclusions they > have come to. > > > >Jo > > > > , Peter VV > <swpgh01 wrote: > >> > >> Grapefruit link to breast cancer > >> > >> Eating too much grapefruit > could increase risks of > >breast cancer > >> > >> Eating grapefruit every day could raise the risk > of developing > >breast cancer by almost a third, US scientists say. > A study of > >50,000 post-menopausal women found eating just a > quarter of a > >grapefruit daily raised the risk by up to 30%. > The fruit is thought > >to boost levels of oestrogen - the hormone > associated with a higher > >risk of the disease, the British Journal of Cancer > reported. But > >the researchers and other experts said more > research was still > >needed. This is an interesting > study, but is simply > >a piece of the jigsaw that will eventually help us > to understand how > >our diets affect our health > >> > >> > >> Dr Joanne Lunn > >> > >> The women had to fill in questionnaires saying > how often they ate > >grapefruit and how big their portions were. > Oestrogen important > >The researchers, at the universities of South > California and Hawaii, > >found that women who ate one quarter of a > grapefruit or more every > >day had a higher risk of breast cancer than those > who did not eat the > >fruit at all. Previous studies have shown that a > molecule called > >cytochrome P450 3A4 (CYP3A4) is involved in > metabolising oestrogen > >hormones. And grapefruit may boost blood > oestrogen levels by > >inhibiting this molecule, allowing the hormones to > build up. The > >researchers found that in women who ate at least a > quarter of a > >grapefruit daily, levels of oestrogen were higher. > They said: " It > >is well established that oestrogen is associated > with breast cancer > >risk. " Therefore, if grapefruit intake affects > oestrogen metabolism > >leading to higher circulating levels, then it is > biologically > >plausible that regular intake of grapefruit would > >> increase a woman's risk of breast cancer. " > More research And > >they said this was the first time a commonly eaten > food had been > >linked to an increased risk of breast cancer in > older women. > >However, they warned that more research was needed > to confirm the > >findings which may have been affected because they > only took into > >account intake of the fruit, but not grapefruit > juice. Breast > >cancer accounts for almost a third of all cancers > in women, and > >previous lifestyle factors linked to the disease > include drinking > >alcohol and being overweight. Dr Joanne Lunn, a > nutrition scientist > >at the British Nutrition Foundation said: " This is > an interesting > >study of a large group of post-menopausal women > whose diet and health > >have been followed for many years. " However, this > study is simply a > >piece of the jigsaw that will eventually help us to > understand how > >our diets affect our health. " Although we are > beginning to get a > >better awareness of how our diets can modify the > risk of > >> diseases such as cancer, we are still a long > way from identifying > >particular foods that might specifically increase > or decrease > >risk. " However, she said that some dietary > patterns are associated > >with a reduced risk of certain cancers and that a > diet rich in a > >variety of different fruits and vegetables could > help reduce the risk > >of heart disease and some cancers. > >> > >> > >> > >> Peter H > >> > >> > >> > >> > >> Mail is the world's favourite email. > Don't settle for less, > >sign up for your freeaccount today. > >> > > > > > > > > > >To send an email to > - > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 17, 2007 Report Share Posted July 17, 2007 I know I aint bright, but can men get breast cancer ( stop laughing at me please!), does it affect muscle, or what.................scuse my ignorance. I eat half a grapefruit every morning............ The Valley Vegan...........heartwerk <jo.heartwork wrote: I would like to know what other constants they considered in their research, before I believe this. Incidentally I don't eat grapefruits at all, but doubt the conclusions they have come to.Jo , Peter VV <swpgh01 wrote:>> Grapefruit link to breast cancer > > Eating too much grapefruit could increase risks of breast cancer> > Eating grapefruit every day could raise the risk of developing breast cancer by almost a third, US scientists say. A study of 50,000 post-menopausal women found eating just a quarter of a grapefruit daily raised the risk by up to 30%. The fruit is thought to boost levels of oestrogen - the hormone associated with a higher risk of the disease, the British Journal of Cancer reported. But the researchers and other experts said more research was still needed. This is an interesting study, but is simply a piece of the jigsaw that will eventually help us to understand how our diets affect our health > > > Dr Joanne Lunn> > The women had to fill in questionnaires saying how often they ate grapefruit and how big their portions were. Oestrogen important The researchers, at the universities of South California and Hawaii, found that women who ate one quarter of a grapefruit or more every day had a higher risk of breast cancer than those who did not eat the fruit at all. Previous studies have shown that a molecule called cytochrome P450 3A4 (CYP3A4) is involved in metabolising oestrogen hormones. And grapefruit may boost blood oestrogen levels by inhibiting this molecule, allowing the hormones to build up. The researchers found that in women who ate at least a quarter of a grapefruit daily, levels of oestrogen were higher. They said: "It is well established that oestrogen is associated with breast cancer risk. "Therefore, if grapefruit intake affects oestrogen metabolism leading to higher circulating levels, then it is biologically plausible that regular intake of grapefruit would> increase a woman's risk of breast cancer." More research And they said this was the first time a commonly eaten food had been linked to an increased risk of breast cancer in older women. However, they warned that more research was needed to confirm the findings which may have been affected because they only took into account intake of the fruit, but not grapefruit juice. Breast cancer accounts for almost a third of all cancers in women, and previous lifestyle factors linked to the disease include drinking alcohol and being overweight. Dr Joanne Lunn, a nutrition scientist at the British Nutrition Foundation said: "This is an interesting study of a large group of post-menopausal women whose diet and health have been followed for many years. "However, this study is simply a piece of the jigsaw that will eventually help us to understand how our diets affect our health. "Although we are beginning to get a better awareness of how our diets can modify the risk of> diseases such as cancer, we are still a long way from identifying particular foods that might specifically increase or decrease risk." However, she said that some dietary patterns are associated with a reduced risk of certain cancers and that a diet rich in a variety of different fruits and vegetables could help reduce the risk of heart disease and some cancers. > > > > Peter H > > > > > Mail is the world's favourite email. Don't settle for less, sign up for your freeaccount today.>Peter H Mail is the world's favourite email. Don't settle for less, sign up for your free account today. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 17, 2007 Report Share Posted July 17, 2007 I _love_ grapefruit. Potatoes and grapefruits are my favorite foods. And I have a history of breast cancer in my family, but I'm not giving it up. (Although I don't eat it every day.) Peter, stick with your yummy fruit. As for male breast cancer, here's a link for you: http://www.cancer.org/docroot/CRI/content/CRI_2_4_1X_What_is_male_breast_cancer_\ 28.asp Tracy --- Peter VV <swpgh01.t21 wrote: > I know I aint bright, but can men get breast cancer > ( stop laughing at me please!), does it affect > muscle, or what.................scuse my ignorance. > > I eat half a grapefruit every morning............ > > The Valley Vegan........... > > heartwerk <jo.heartwork wrote: > I would like to know what other constants > they considered in their > research, before I believe this. Incidentally I > don't eat > grapefruits at all, but doubt the conclusions they > have come to. > > Jo > > , Peter VV > <swpgh01 wrote: > > > > Grapefruit link to breast cancer > > > > Eating too much grapefruit could increase risks of > > breast cancer > > > > Eating grapefruit every day could raise the risk > of developing > breast cancer by almost a third, US scientists say. > A study of > 50,000 post-menopausal women found eating just a > quarter of a > grapefruit daily raised the risk by up to 30%. The > fruit is thought > to boost levels of oestrogen - the hormone > associated with a higher > risk of the disease, the British Journal of Cancer > reported. But > the researchers and other experts said more research > was still > needed. This is an interesting study, but is simply > a piece of the jigsaw that will eventually help us > to understand how > our diets affect our health > > > > > > Dr Joanne Lunn > > > > The women had to fill in questionnaires saying how > often they ate > grapefruit and how big their portions were. > Oestrogen important > The researchers, at the universities of South > California and Hawaii, > found that women who ate one quarter of a grapefruit > or more every > day had a higher risk of breast cancer than those > who did not eat the > fruit at all. Previous studies have shown that a > molecule called > cytochrome P450 3A4 (CYP3A4) is involved in > metabolising oestrogen > hormones. And grapefruit may boost blood oestrogen > levels by > inhibiting this molecule, allowing the hormones to > build up. The > researchers found that in women who ate at least a > quarter of a > grapefruit daily, levels of oestrogen were higher. > They said: " It > is well established that oestrogen is associated > with breast cancer > risk. " Therefore, if grapefruit intake affects > oestrogen metabolism > leading to higher circulating levels, then it is > biologically > plausible that regular intake of grapefruit would > > increase a woman's risk of breast cancer. " More > research And > they said this was the first time a commonly eaten > food had been > linked to an increased risk of breast cancer in > older women. > However, they warned that more research was needed > to confirm the > findings which may have been affected because they > only took into > account intake of the fruit, but not grapefruit > juice. Breast > cancer accounts for almost a third of all cancers in > women, and > previous lifestyle factors linked to the disease > include drinking > alcohol and being overweight. Dr Joanne Lunn, a > nutrition scientist > at the British Nutrition Foundation said: " This is > an interesting > study of a large group of post-menopausal women > whose diet and health > have been followed for many years. " However, this > study is simply a > piece of the jigsaw that will eventually help us to > understand how > our diets affect our health. " Although we are > beginning to get a > better awareness of how our diets can modify the > risk of > > diseases such as cancer, we are still a long way > from identifying > particular foods that might specifically increase or > decrease > risk. " However, she said that some dietary patterns > are associated > with a reduced risk of certain cancers and that a > diet rich in a > variety of different fruits and vegetables could > help reduce the risk > of heart disease and some cancers. > > > > > > > > Peter H > > > > > > > > > > Mail is the world's favourite email. Don't > settle for less, > sign up for your freeaccount today. > > Peter H > > > > > Mail is the world's favourite email. Don't > settle for less, sign up for your freeaccount today. ______________________________\ ____ Food fight? Enjoy some healthy debate in the Answers Food & Drink Q & A. http://answers./dir/?link=list & sid=396545367 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 17, 2007 Report Share Posted July 17, 2007 you can get cancer at any part of yer body.... yes, men can get breast cancer, its just more prevalent in womyns generally, breast cancer affects the tissues of the breast, meaning the ducts and the milk producing areas, which name escapes me at the moment bois and gurls are both born with ducts, but at puberty womyns start producing more as their hormones turn on Peter VV Jul 17, 2007 1:01 PM Re: Re: Grapefruit link to breast cancer I know I aint bright, but can men get breast cancer ( stop laughing at me please!), does it affect muscle, or what.................scuse my ignorance. I eat half a grapefruit every morning............ The Valley Vegan...........heartwerk <jo.heartwork > wrote: I would like to know what other constants they considered in their research, before I believe this. Incidentally I don't eat grapefruits at all, but doubt the conclusions they have come to.Jo , Peter VV <swpgh01 wrote:>> Grapefruit link to breast cancer > > Eating too much grapefruit could increase risks of breast cancer> > Eating grapefruit every day could raise the risk of developing breast cancer by almost a third, US scientists say. A study of 50,000 post-menopausal women found eating just a quarter of a grapefruit daily raised the risk by up to 30%. The fruit is thought to boost levels of oestrogen - the hormone associated with a higher risk of the disease, the British Journal of Cancer reported. But the researchers and other experts said more research was still needed. This is an interesting study, but is simply a piece of the jigsaw that will eventually help us to understand how our diets affect our health > > > Dr Joanne Lunn> > The women had to fill in questionnaires saying how often they ate grapefruit and how big their portions were. Oestrogen important The researchers, at the universities of South California and Hawaii, found that women who ate one quarter of a grapefruit or more every day had a higher risk of breast cancer than those who did not eat the fruit at all. Previous studies have shown that a molecule called cytochrome P450 3A4 (CYP3A4) is involved in metabolising oestrogen hormones. And grapefruit may boost blood oestrogen levels by inhibiting this molecule, allowing the hormones to build up. The researchers found that in women who ate at least a quarter of a grapefruit daily, levels of oestrogen were higher. They said: "It is well established that oestrogen is associated with breast cancer risk. "Therefore, if grapefruit intake affects oestrogen metabolism leading to higher circulating levels, then it is biologically plausible that regular intake of grapefruit would> increase a woman's risk of breast cancer." More research And they said this was the first time a commonly eaten food had been linked to an increased risk of breast cancer in older women. However, they warned that more research was needed to confirm the findings which may have been affected because they only took into account intake of the fruit, but not grapefruit juice. Breast cancer accounts for almost a third of all cancers in women, and previous lifestyle factors linked to the disease include drinking alcohol and being overweight. Dr Joanne Lunn, a nutrition scientist at the British Nutrition Foundation said: "This is an interesting study of a large group of post-menopausal women whose diet and health have been followed for many years. "However, this study is simply a piece of the jigsaw that will eventually help us to understand how our diets affect our health. "Although we are beginning to get a better awareness of how our diets can modify the risk of> diseases such as cancer, we are still a long way from identifying particular foods that might specifically increase or decrease risk." However, she said that some dietary patterns are associated with a reduced risk of certain cancers and that a diet rich in a variety of different fruits and vegetables could help reduce the risk of heart disease and some cancers. > > > > Peter H > > > > > Mail is the world's favourite email. Don't settle for less, sign up for your freeaccount today.> Peter H Mail is the world's favourite email. Don't settle for less, sign up for your free account today. When I see the price that you pay I don't wanna grow up I don't ever want to be that way I don't wanna grow up Seems that folks turn into things that they never want Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 17, 2007 Report Share Posted July 17, 2007 Thanks Tracy............ The Valley Vegan.............."Tracy H." <denise_h22 wrote: I _love_ grapefruit. Potatoes and grapefruits are myfavorite foods. And I have a history of breast cancerin my family, but I'm not giving it up. (Although Idon't eat it every day.)Peter, stick with your yummy fruit. As for male breastcancer, here's a link for you:http://www.cancer.org/docroot/CRI/content/CRI_2_4_1X_What_is_male_breast_cancer_28.aspTracy--- Peter VV <swpgh01.t21 (AT) btinternet (DOT) com> wrote:> I know I aint bright, but can men get breast cancer> ( stop laughing at me please!), does it affect> muscle, or what.................scuse my ignorance.> > I eat half a grapefruit every morning............> > The Valley Vegan...........> > heartwerk <jo.heartwork > wrote:> I would like to know what other constants> they considered in their > research, before I believe this. Incidentally I> don't eat > grapefruits at all, but doubt the conclusions they> have come to.> > Jo> > , Peter VV> <swpgh01 wrote:> >> > Grapefruit link to breast cancer > > > > Eating too much grapefruit could increase risks of> > breast cancer> > > > Eating grapefruit every day could raise the risk> of developing > breast cancer by almost a third, US scientists say.> A study of > 50,000 post-menopausal women found eating just a> quarter of a > grapefruit daily raised the risk by up to 30%. The> fruit is thought > to boost levels of oestrogen - the hormone> associated with a higher > risk of the disease, the British Journal of Cancer> reported. But > the researchers and other experts said more research> was still > needed. This is an interesting study, but is simply > a piece of the jigsaw that will eventually help us> to understand how > our diets affect our health > > > > > > Dr Joanne Lunn> > > > The women had to fill in questionnaires saying how> often they ate > grapefruit and how big their portions were.> Oestrogen important > The researchers, at the universities of South> California and Hawaii, > found that women who ate one quarter of a grapefruit> or more every > day had a higher risk of breast cancer than those> who did not eat the > fruit at all. Previous studies have shown that a> molecule called > cytochrome P450 3A4 (CYP3A4) is involved in> metabolising oestrogen > hormones. And grapefruit may boost blood oestrogen> levels by > inhibiting this molecule, allowing the hormones to> build up. The > researchers found that in women who ate at least a> quarter of a > grapefruit daily, levels of oestrogen were higher.> They said: "It > is well established that oestrogen is associated> with breast cancer > risk. "Therefore, if grapefruit intake affects> oestrogen metabolism > leading to higher circulating levels, then it is> biologically > plausible that regular intake of grapefruit would> > increase a woman's risk of breast cancer." More> research And > they said this was the first time a commonly eaten> food had been > linked to an increased risk of breast cancer in> older women. > However, they warned that more research was needed> to confirm the > findings which may have been affected because they> only took into > account intake of the fruit, but not grapefruit> juice. Breast > cancer accounts for almost a third of all cancers in> women, and > previous lifestyle factors linked to the disease> include drinking > alcohol and being overweight. Dr Joanne Lunn, a> nutrition scientist > at the British Nutrition Foundation said: "This is> an interesting > study of a large group of post-menopausal women> whose diet and health > have been followed for many years. "However, this> study is simply a > piece of the jigsaw that will eventually help us to> understand how > our diets affect our health. "Although we are> beginning to get a > better awareness of how our diets can modify the> risk of> > diseases such as cancer, we are still a long way> from identifying > particular foods that might specifically increase or> decrease > risk." However, she said that some dietary patterns> are associated > with a reduced risk of certain cancers and that a> diet rich in a > variety of different fruits and vegetables could> help reduce the risk > of heart disease and some cancers. > > > > > > > > Peter H > > > > > > > > > > Mail is the world's favourite email. Don't> settle for less, > sign up for your freeaccount today.> >> > > > > > > Peter H > > > > > Mail is the world's favourite email. Don't> settle for less, sign up for your freeaccount today.________Food fight? Enjoy some healthy debate in the Answers Food & Drink Q & A.http://answers./dir/?link=list & sid=396545367Peter H The all-new Mail goes wherever you go - free your email address from your Internet provider. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 18, 2007 Report Share Posted July 18, 2007 Things are not always what they seem, are they? T. Colin Campbell (The China Study), who discovered dioxin, was working on a project to investigate the high prevalence of liver cancer in filipino children. It was thought the cause was aflatoxin, a mold found in peanuts and corn, one of the most potent carcinogens ever discovered. To combat childhood malnutrition, this project was also supposed to ensure children got as much protein as possible. It was widely thought at that time that childhood malnutrition was caused by lack of protein, especially the animal variety. Studies then revealed that: 1) children who ate the highest-protein diets were the ones most likely to get liver cancer, and 2) rats who were fed both aflatoxin and 20% of their diet as protein got liver cancer, while rats who were fed aflatoxin and 5% of their diet as protein did NOT get liver cancer. These results were 0% and 100%; 5% protein + carcinogen = NO cancer; 20% protein + carcinogen = everyone gets cancer. What does this have to do with grapefruits? Just what a few of you have been pointing out. Just as the aflatoxin wasn't the entire picture, neither are those grapefruits. And, by the way, I wonder how many people in the world die from eating grapefruit? Why don't they compare the risk of cancer from grapefruit with that of animal products? Maybe when combined with a high level of protein, you get cancer? We are right to ask questions when we see a study like this one. I always want to follow the money. For example, who funded this grapefruit study? Marcy - yarrow Tuesday, July 17, 2007 10:23 AM Re: Grapefruit link to breast cancer Exactly! At first I thought, what if all the grapefruit eaters are eating sausage and bacon for breakfast, and eat grapefruit to balance the fat? I have some neighbors who were doing this for a while. Or perhaps the grapefruits had some pesticide residue that caused this effect.But then I realized the study posited a chemical pathway implicating grapefruit and also played loose with statistics. I'm not sure what the researchers mean by "higher risk": do they mean that more women developed BC? Or that they assume the risk of developing it is higher because grapefruit inhibits cytochrome P450 3A4 (CYP3A4) and thus allows higher estrogen levels? Maybe what they measured was estrogen levels, which are correlated with higher risk of bc.Re statistics: the "up to 30 percent higher" has no meaning unless you know what it's based on. So if the risk is 1 percent, then grapefruit would make it 1.3 percent. If it's 15 percent, it goes to 22 percent. But the way it's written and the way it's often interpreted in the lay press is that the risk goes from 1 to 31 percent, or from 15 to 45 percent. Huge difference.I eat grapefruit only in the winter, as a fruit, a whole one at a time.At 7:00 AM +0000 7/17/07, heartwerk wrote:>I would like to know what other constants they considered in their>research, before I believe this. Incidentally I don't eat>grapefruits at all, but doubt the conclusions they have come to.>>Jo>> , Peter VV <swpgh01 wrote:>>>> Grapefruit link to breast cancer>>>> Eating too much grapefruit could increase risks of>breast cancer>>>> Eating grapefruit every day could raise the risk of developing>breast cancer by almost a third, US scientists say. A study of>50,000 post-menopausal women found eating just a quarter of a>grapefruit daily raised the risk by up to 30%. The fruit is thought>to boost levels of oestrogen - the hormone associated with a higher>risk of the disease, the British Journal of Cancer reported. But>the researchers and other experts said more research was still>needed. This is an interesting study, but is simply>a piece of the jigsaw that will eventually help us to understand how>our diets affect our health>>>>>> Dr Joanne Lunn>>>> The women had to fill in questionnaires saying how often they ate>grapefruit and how big their portions were. Oestrogen important>The researchers, at the universities of South California and Hawaii,>found that women who ate one quarter of a grapefruit or more every>day had a higher risk of breast cancer than those who did not eat the>fruit at all. Previous studies have shown that a molecule called>cytochrome P450 3A4 (CYP3A4) is involved in metabolising oestrogen>hormones. And grapefruit may boost blood oestrogen levels by>inhibiting this molecule, allowing the hormones to build up. The>researchers found that in women who ate at least a quarter of a>grapefruit daily, levels of oestrogen were higher. They said: "It>is well established that oestrogen is associated with breast cancer>risk. "Therefore, if grapefruit intake affects oestrogen metabolism>leading to higher circulating levels, then it is biologically>plausible that regular intake of grapefruit would>> increase a woman's risk of breast cancer." More research And>they said this was the first time a commonly eaten food had been>linked to an increased risk of breast cancer in older women.>However, they warned that more research was needed to confirm the>findings which may have been affected because they only took into>account intake of the fruit, but not grapefruit juice. Breast>cancer accounts for almost a third of all cancers in women, and>previous lifestyle factors linked to the disease include drinking>alcohol and being overweight. Dr Joanne Lunn, a nutrition scientist>at the British Nutrition Foundation said: "This is an interesting>study of a large group of post-menopausal women whose diet and health>have been followed for many years. "However, this study is simply a>piece of the jigsaw that will eventually help us to understand how>our diets affect our health. "Although we are beginning to get a>better awareness of how our diets can modify the risk of>> diseases such as cancer, we are still a long way from identifying>particular foods that might specifically increase or decrease>risk." However, she said that some dietary patterns are associated>with a reduced risk of certain cancers and that a diet rich in a>variety of different fruits and vegetables could help reduce the risk>of heart disease and some cancers.>>>>>>>> Peter H>>>>>>>> >> Mail is the world's favourite email. Don't settle for less,>sign up for your freeaccount today.>>>>>>>To send an email to - > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 18, 2007 Report Share Posted July 18, 2007 (blushing) Well, today I had on my writer hat. (And, like Mr. Science, I have a degree -- in science!) I've read a lot of these studies in the newspaper, and when you go back to the original paper, usually the conclusion is something like this: " we found a correlation between x and y, and further studies are warranted to determine the z. " But in the newspaper, the research is invariably reported as " z cures x! " or " y causes cancer! " I know the headlines are not written by the writers, and often the writers are not sci/med writers (many newspapers have been dropping the science section of the paper), so if the press release they used to write the story was factual, by the time it gets into the paper it's been through so many reinterpretations and simplifications (probably in an attempt to make it sound relevant and significant) that it's become republican (adj., not reality-based). At 12:00 PM -0700 7/17/07, Tracy H. wrote: >Yarrow, you sound brilliant! What do you do for a >living? > >--- yarrow wrote: > >> Exactly! At first I thought, what if all the >> grapefruit eaters are >> eating sausage and bacon for breakfast, and eat >> grapefruit to balance >> the fat? I have some neighbors who were doing this >> for a while. Or >> perhaps the grapefruits had some pesticide residue >> that caused this >> effect. >> >> But then I realized the study posited a chemical >> pathway implicating >> grapefruit and also played loose with statistics. >> I'm not sure what >> the researchers mean by " higher risk " : do they mean >> that more women >> developed BC? Or that they assume the risk of >> developing it is higher >> because grapefruit inhibits cytochrome P450 3A4 >> (CYP3A4) and thus >> allows higher estrogen levels? Maybe what they >> measured was estrogen >> levels, which are correlated with higher risk of bc. >> >> Re statistics: the " up to 30 percent higher " has no >> meaning unless >> you know what it's based on. So if the risk is 1 >> percent, then >> grapefruit would make it 1.3 percent. If it's 15 >> percent, it goes to >> 22 percent. But the way it's written and the way >> it's often >> interpreted in the lay press is that the risk goes >> from 1 to 31 >> percent, or from 15 to 45 percent. Huge difference. >> >> I eat grapefruit only in the winter, as a fruit, a >> whole one at a time. >> >> >> At 7:00 AM +0000 7/17/07, heartwerk wrote: >> >I would like to know what other constants they >> considered in their >> >research, before I believe this. Incidentally I >> don't eat >> >grapefruits at all, but doubt the conclusions they >> have come to. >> > >> >Jo >> > >> > , Peter VV >> <swpgh01 wrote: >> >> >> >> Grapefruit link to breast cancer >> >> >> >> Eating too much grapefruit >> could increase risks of >> >breast cancer >> >> >> >> Eating grapefruit every day could raise the risk >> of developing >> >breast cancer by almost a third, US scientists say. >> A study of >> >50,000 post-menopausal women found eating just a >> quarter of a >> >grapefruit daily raised the risk by up to 30%. >> The fruit is thought >> >to boost levels of oestrogen - the hormone >> associated with a higher >> >risk of the disease, the British Journal of Cancer >> reported. But >> >the researchers and other experts said more >> research was still >> >needed. This is an interesting >> study, but is simply >> >a piece of the jigsaw that will eventually help us >> to understand how >> >our diets affect our health >> >> >> >> >> >> Dr Joanne Lunn >> >> >> >> The women had to fill in questionnaires saying >> how often they ate >> >grapefruit and how big their portions were. >> Oestrogen important >> >The researchers, at the universities of South >> California and Hawaii, >> >found that women who ate one quarter of a >> grapefruit or more every >> >day had a higher risk of breast cancer than those >> who did not eat the >> >fruit at all. Previous studies have shown that a >> molecule called >> >cytochrome P450 3A4 (CYP3A4) is involved in >> metabolising oestrogen >> >hormones. And grapefruit may boost blood >> oestrogen levels by >> >inhibiting this molecule, allowing the hormones to >> build up. The >> >researchers found that in women who ate at least a >> quarter of a >> >grapefruit daily, levels of oestrogen were higher. >> They said: " It >> >is well established that oestrogen is associated >> with breast cancer >> >risk. " Therefore, if grapefruit intake affects >> oestrogen metabolism >> >leading to higher circulating levels, then it is >> biologically >> >plausible that regular intake of grapefruit would >> >> increase a woman's risk of breast cancer. " >> More research And >> >they said this was the first time a commonly eaten >> food had been >> >linked to an increased risk of breast cancer in >> older women. >> >However, they warned that more research was needed >> to confirm the >> >findings which may have been affected because they >> only took into >> >account intake of the fruit, but not grapefruit >> juice. Breast >> >cancer accounts for almost a third of all cancers >> in women, and >> >previous lifestyle factors linked to the disease >> include drinking >> >alcohol and being overweight. Dr Joanne Lunn, a >> nutrition scientist >> >at the British Nutrition Foundation said: " This is >> an interesting >> >study of a large group of post-menopausal women >> whose diet and health >> >have been followed for many years. " However, this >> study is simply a >> >piece of the jigsaw that will eventually help us to >> understand how >> >our diets affect our health. " Although we are >> beginning to get a >> >better awareness of how our diets can modify the >> risk of >> >> diseases such as cancer, we are still a long >> way from identifying >> >particular foods that might specifically increase >> or decrease >> >risk. " However, she said that some dietary >> patterns are associated >> >with a reduced risk of certain cancers and that a >> diet rich in a >> >variety of different fruits and vegetables could >> help reduce the risk >> >of heart disease and some cancers. >> >> >> >> >> >> >> >> Peter H >> >> >> >> >> >> >> >> >> >> Mail is the world's favourite email. >> Don't settle for less, >> >sign up for your freeaccount today. >> >> >> > >> > >> > >> > >> >To send an email to >> - >> > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 18, 2007 Report Share Posted July 18, 2007 Hi Peter Yes, men can and do get breast cancer. Men have a small amount of the same breast tissue as women and it is this that is affected. It presents as a lump underneath the nipple or areola area, and is just as dangerous as women's breast cancer. I believe about 200 men a year get breast cancer. Jo , Peter VV <swpgh01.t21 wrote: > > I know I aint bright, but can men get breast cancer ( stop laughing at me please!), does it affect muscle, or what.................scuse my ignorance. > > I eat half a grapefruit every morning............ > > The Valley Vegan........... > > heartwerk <jo.heartwork wrote: > I would like to know what other constants they considered in their > research, before I believe this. Incidentally I don't eat > grapefruits at all, but doubt the conclusions they have come to. > > Jo > > , Peter VV <swpgh01@> wrote: > > > > Grapefruit link to breast cancer > > > > Eating too much grapefruit could increase risks of > breast cancer > > > > Eating grapefruit every day could raise the risk of developing > breast cancer by almost a third, US scientists say. A study of > 50,000 post-menopausal women found eating just a quarter of a > grapefruit daily raised the risk by up to 30%. The fruit is thought > to boost levels of oestrogen - the hormone associated with a higher > risk of the disease, the British Journal of Cancer reported. But > the researchers and other experts said more research was still > needed. This is an interesting study, but is simply > a piece of the jigsaw that will eventually help us to understand how > our diets affect our health > > > > > > Dr Joanne Lunn > > > > The women had to fill in questionnaires saying how often they ate > grapefruit and how big their portions were. Oestrogen important > The researchers, at the universities of South California and Hawaii, > found that women who ate one quarter of a grapefruit or more every > day had a higher risk of breast cancer than those who did not eat the > fruit at all. Previous studies have shown that a molecule called > cytochrome P450 3A4 (CYP3A4) is involved in metabolising oestrogen > hormones. And grapefruit may boost blood oestrogen levels by > inhibiting this molecule, allowing the hormones to build up. The > researchers found that in women who ate at least a quarter of a > grapefruit daily, levels of oestrogen were higher. They said: " It > is well established that oestrogen is associated with breast cancer > risk. " Therefore, if grapefruit intake affects oestrogen metabolism > leading to higher circulating levels, then it is biologically > plausible that regular intake of grapefruit would > > increase a woman's risk of breast cancer. " More research And > they said this was the first time a commonly eaten food had been > linked to an increased risk of breast cancer in older women. > However, they warned that more research was needed to confirm the > findings which may have been affected because they only took into > account intake of the fruit, but not grapefruit juice. Breast > cancer accounts for almost a third of all cancers in women, and > previous lifestyle factors linked to the disease include drinking > alcohol and being overweight. Dr Joanne Lunn, a nutrition scientist > at the British Nutrition Foundation said: " This is an interesting > study of a large group of post-menopausal women whose diet and health > have been followed for many years. " However, this study is simply a > piece of the jigsaw that will eventually help us to understand how > our diets affect our health. " Although we are beginning to get a > better awareness of how our diets can modify the risk of > > diseases such as cancer, we are still a long way from identifying > particular foods that might specifically increase or decrease > risk. " However, she said that some dietary patterns are associated > with a reduced risk of certain cancers and that a diet rich in a > variety of different fruits and vegetables could help reduce the risk > of heart disease and some cancers. > > > > > > > > Peter H > > > > > > > > > > Mail is the world's favourite email. Don't settle for less, > sign up for your freeaccount today. > > Peter H > > > > > Mail is the world's favourite email. Don't settle for less, sign up for your freeaccount today. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 18, 2007 Report Share Posted July 18, 2007 Hi Marcy I always like to know who is funding the research too. Jo , " Marcy " <imgreen03 wrote: > > Things are not always what they seem, are they? > > T. Colin Campbell (The China Study), who discovered dioxin, was working on a project to investigate the high prevalence of liver cancer in filipino children. It was thought the cause was aflatoxin, a mold found in peanuts and corn, one of the most potent carcinogens ever discovered. > > To combat childhood malnutrition, this project was also supposed to ensure children got as much protein as possible. It was widely thought at that time that childhood malnutrition was caused by lack of protein, especially the animal variety. > > Studies then revealed that: > 1) children who ate the highest-protein diets were the ones most likely to get liver cancer, and > 2) rats who were fed both aflatoxin and 20% of their diet as protein got liver cancer, while rats who were fed aflatoxin and 5% of their diet as protein did NOT get liver cancer. These results were 0% and 100%; 5% protein + carcinogen = NO cancer; 20% protein + carcinogen = everyone gets cancer. > > What does this have to do with grapefruits? Just what a few of you have been pointing out. Just as the aflatoxin wasn't the entire picture, neither are those grapefruits. > > And, by the way, I wonder how many people in the world die from eating grapefruit? Why don't they compare the risk of cancer from grapefruit with that of animal products? > > Maybe when combined with a high level of protein, you get cancer? > > We are right to ask questions when we see a study like this one. I always want to follow the money. For example, who funded this grapefruit study? > > Marcy > > > > - > yarrow > > Tuesday, July 17, 2007 10:23 AM > Re: Grapefruit link to breast cancer > > > Exactly! At first I thought, what if all the grapefruit eaters are > eating sausage and bacon for breakfast, and eat grapefruit to balance > the fat? I have some neighbors who were doing this for a while. Or > perhaps the grapefruits had some pesticide residue that caused this > effect. > > But then I realized the study posited a chemical pathway implicating > grapefruit and also played loose with statistics. I'm not sure what > the researchers mean by " higher risk " : do they mean that more women > developed BC? Or that they assume the risk of developing it is higher > because grapefruit inhibits cytochrome P450 3A4 (CYP3A4) and thus > allows higher estrogen levels? Maybe what they measured was estrogen > levels, which are correlated with higher risk of bc. > > Re statistics: the " up to 30 percent higher " has no meaning unless > you know what it's based on. So if the risk is 1 percent, then > grapefruit would make it 1.3 percent. If it's 15 percent, it goes to > 22 percent. But the way it's written and the way it's often > interpreted in the lay press is that the risk goes from 1 to 31 > percent, or from 15 to 45 percent. Huge difference. > > I eat grapefruit only in the winter, as a fruit, a whole one at a time. > > At 7:00 AM +0000 7/17/07, heartwerk wrote: > >I would like to know what other constants they considered in their > >research, before I believe this. Incidentally I don't eat > >grapefruits at all, but doubt the conclusions they have come to. > > > >Jo > > > > , Peter VV <swpgh01@> wrote: > >> > >> Grapefruit link to breast cancer > >> > >> Eating too much grapefruit could increase risks of > >breast cancer > >> > >> Eating grapefruit every day could raise the risk of developing > >breast cancer by almost a third, US scientists say. A study of > >50,000 post-menopausal women found eating just a quarter of a > >grapefruit daily raised the risk by up to 30%. The fruit is thought > >to boost levels of oestrogen - the hormone associated with a higher > >risk of the disease, the British Journal of Cancer reported. But > >the researchers and other experts said more research was still > >needed. This is an interesting study, but is simply > >a piece of the jigsaw that will eventually help us to understand how > >our diets affect our health > >> > >> > >> Dr Joanne Lunn > >> > >> The women had to fill in questionnaires saying how often they ate > >grapefruit and how big their portions were. Oestrogen important > >The researchers, at the universities of South California and Hawaii, > >found that women who ate one quarter of a grapefruit or more every > >day had a higher risk of breast cancer than those who did not eat the > >fruit at all. Previous studies have shown that a molecule called > >cytochrome P450 3A4 (CYP3A4) is involved in metabolising oestrogen > >hormones. And grapefruit may boost blood oestrogen levels by > >inhibiting this molecule, allowing the hormones to build up. The > >researchers found that in women who ate at least a quarter of a > >grapefruit daily, levels of oestrogen were higher. They said: " It > >is well established that oestrogen is associated with breast cancer > >risk. " Therefore, if grapefruit intake affects oestrogen metabolism > >leading to higher circulating levels, then it is biologically > >plausible that regular intake of grapefruit would > >> increase a woman's risk of breast cancer. " More research And > >they said this was the first time a commonly eaten food had been > >linked to an increased risk of breast cancer in older women. > >However, they warned that more research was needed to confirm the > >findings which may have been affected because they only took into > >account intake of the fruit, but not grapefruit juice. Breast > >cancer accounts for almost a third of all cancers in women, and > >previous lifestyle factors linked to the disease include drinking > >alcohol and being overweight. Dr Joanne Lunn, a nutrition scientist > >at the British Nutrition Foundation said: " This is an interesting > >study of a large group of post-menopausal women whose diet and health > >have been followed for many years. " However, this study is simply a > >piece of the jigsaw that will eventually help us to understand how > >our diets affect our health. " Although we are beginning to get a > >better awareness of how our diets can modify the risk of > >> diseases such as cancer, we are still a long way from identifying > >particular foods that might specifically increase or decrease > >risk. " However, she said that some dietary patterns are associated > >with a reduced risk of certain cancers and that a diet rich in a > >variety of different fruits and vegetables could help reduce the risk > >of heart disease and some cancers. > >> > >> > >> > >> Peter H > >> > >> > >> > >> > >> Mail is the world's favourite email. Don't settle for less, > >sign up for your freeaccount today. > >> > > > > > > > > > >To send an email to - > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 18, 2007 Report Share Posted July 18, 2007 A quick word about cancer in non human animals - it is very misleading. The most celebrated is that of smoking. Lab animals didn't contract cancer even after being subjected to 24/7 cigarette smoke, both active and passive. I would go with the human studies. --- Marcy <imgreen03 wrote: > Things are not always what they seem, are they? > > T. Colin Campbell (The China Study), who discovered > dioxin, was working on a project to investigate the > high prevalence of liver cancer in filipino > children. It was thought the cause was aflatoxin, a > mold found in peanuts and corn, one of the most > potent carcinogens ever discovered. > > To combat childhood malnutrition, this project was > also supposed to ensure children got as much protein > as possible. It was widely thought at that time > that childhood malnutrition was caused by lack of > protein, especially the animal variety. > > Studies then revealed that: > 1) children who ate the highest-protein diets were > the ones most likely to get liver cancer, and > 2) rats who were fed both aflatoxin and 20% of > their diet as protein got liver cancer, while rats > who were fed aflatoxin and 5% of their diet as > protein did NOT get liver cancer. These results > were 0% and 100%; 5% protein + carcinogen = NO > cancer; 20% protein + carcinogen = everyone gets > cancer. > > What does this have to do with grapefruits? Just > what a few of you have been pointing out. Just as > the aflatoxin wasn't the entire picture, neither are > those grapefruits. > > And, by the way, I wonder how many people in the > world die from eating grapefruit? Why don't they > compare the risk of cancer from grapefruit with that > of animal products? > > Maybe when combined with a high level of protein, > you get cancer? > > We are right to ask questions when we see a study > like this one. I always want to follow the money. > For example, who funded this grapefruit study? > > Marcy > > > > - > yarrow > > Tuesday, July 17, 2007 10:23 AM > Re: Grapefruit link to > breast cancer > > > Exactly! At first I thought, what if all the > grapefruit eaters are > eating sausage and bacon for breakfast, and eat > grapefruit to balance > the fat? I have some neighbors who were doing this > for a while. Or > perhaps the grapefruits had some pesticide residue > that caused this > effect. > > But then I realized the study posited a chemical > pathway implicating > grapefruit and also played loose with statistics. > I'm not sure what > the researchers mean by " higher risk " : do they > mean that more women > developed BC? Or that they assume the risk of > developing it is higher > because grapefruit inhibits cytochrome P450 3A4 > (CYP3A4) and thus > allows higher estrogen levels? Maybe what they > measured was estrogen > levels, which are correlated with higher risk of > bc. > > Re statistics: the " up to 30 percent higher " has > no meaning unless > you know what it's based on. So if the risk is 1 > percent, then > grapefruit would make it 1.3 percent. If it's 15 > percent, it goes to > 22 percent. But the way it's written and the way > it's often > interpreted in the lay press is that the risk goes > from 1 to 31 > percent, or from 15 to 45 percent. Huge > difference. > > I eat grapefruit only in the winter, as a fruit, a > whole one at a time. > > At 7:00 AM +0000 7/17/07, heartwerk wrote: > >I would like to know what other constants they > considered in their > >research, before I believe this. Incidentally I > don't eat > >grapefruits at all, but doubt the conclusions > they have come to. > > > >Jo > > > > , Peter VV > <swpgh01 wrote: > >> > >> Grapefruit link to breast cancer > >> > >> Eating too much grapefruit could increase risks > of > >breast cancer > >> > >> Eating grapefruit every day could raise the > risk of developing > >breast cancer by almost a third, US scientists > say. A study of > >50,000 post-menopausal women found eating just a > quarter of a > >grapefruit daily raised the risk by up to 30%. > The fruit is thought > >to boost levels of oestrogen - the hormone > associated with a higher > >risk of the disease, the British Journal of > Cancer reported. But > >the researchers and other experts said more > research was still > >needed. This is an interesting study, but is > simply > >a piece of the jigsaw that will eventually help > us to understand how > >our diets affect our health > >> > >> > >> Dr Joanne Lunn > >> > >> The women had to fill in questionnaires saying > how often they ate > >grapefruit and how big their portions were. > Oestrogen important > >The researchers, at the universities of South > California and Hawaii, > >found that women who ate one quarter of a > grapefruit or more every > >day had a higher risk of breast cancer than those > who did not eat the > >fruit at all. Previous studies have shown that a > molecule called > >cytochrome P450 3A4 (CYP3A4) is involved in > metabolising oestrogen > >hormones. And grapefruit may boost blood > oestrogen levels by > >inhibiting this molecule, allowing the hormones > to build up. The > >researchers found that in women who ate at least > a quarter of a > >grapefruit daily, levels of oestrogen were > higher. They said: " It > >is well established that oestrogen is associated > with breast cancer > >risk. " Therefore, if grapefruit intake affects > oestrogen metabolism > >leading to higher circulating levels, then it is > biologically > >plausible that regular intake of grapefruit would > >> increase a woman's risk of breast cancer. " More > research And > >they said this was the first time a commonly > eaten food had been > >linked to an increased risk of breast cancer in > older women. > >However, they warned that more research was > needed to confirm the > >findings which may have been affected because > they only took into > >account intake of the fruit, but not grapefruit > juice. Breast > >cancer accounts for almost a third of all cancers > in women, and > >previous lifestyle factors linked to the disease > include drinking > >alcohol and being overweight. Dr Joanne Lunn, a > nutrition scientist > >at the British Nutrition Foundation said: " This > is an interesting > >study of a large group of post-menopausal women > whose diet and health > >have been followed for many years. " However, this > study is simply a > >piece of the jigsaw that will eventually help us > to understand how > >our diets affect our health. " Although we are > beginning to get a > >better awareness of how our diets can modify the > risk of > >> diseases such as cancer, we are still a long > way from identifying > >particular foods that might specifically increase > or decrease > === message truncated === ______________________________\ ____ Get your own web address. Have a HUGE year through Small Business. http://smallbusiness./domains/?p=BESTDEAL Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 18, 2007 Report Share Posted July 18, 2007 Hi Peter It's much more rare in men, but it is possible - it affects the tissue of the breasts (which men do have!) BB Peter - Peter VV Tuesday, July 17, 2007 9:01 PM Re: Re: Grapefruit link to breast cancer I know I aint bright, but can men get breast cancer ( stop laughing at me please!), does it affect muscle, or what.................scuse my ignorance. I eat half a grapefruit every morning............ The Valley Vegan...........heartwerk <jo.heartwork wrote: I would like to know what other constants they considered in their research, before I believe this. Incidentally I don't eat grapefruits at all, but doubt the conclusions they have come to.Jo , Peter VV <swpgh01 wrote:>> Grapefruit link to breast cancer > > Eating too much grapefruit could increase risks of breast cancer> > Eating grapefruit every day could raise the risk of developing breast cancer by almost a third, US scientists say. A study of 50,000 post-menopausal women found eating just a quarter of a grapefruit daily raised the risk by up to 30%. The fruit is thought to boost levels of oestrogen - the hormone associated with a higher risk of the disease, the British Journal of Cancer reported. But the researchers and other experts said more research was still needed. This is an interesting study, but is simply a piece of the jigsaw that will eventually help us to understand how our diets affect our health > > > Dr Joanne Lunn> > The women had to fill in questionnaires saying how often they ate grapefruit and how big their portions were. Oestrogen important The researchers, at the universities of South California and Hawaii, found that women who ate one quarter of a grapefruit or more every day had a higher risk of breast cancer than those who did not eat the fruit at all. Previous studies have shown that a molecule called cytochrome P450 3A4 (CYP3A4) is involved in metabolising oestrogen hormones. And grapefruit may boost blood oestrogen levels by inhibiting this molecule, allowing the hormones to build up. The researchers found that in women who ate at least a quarter of a grapefruit daily, levels of oestrogen were higher. They said: "It is well established that oestrogen is associated with breast cancer risk. "Therefore, if grapefruit intake affects oestrogen metabolism leading to higher circulating levels, then it is biologically plausible that regular intake of grapefruit would> increase a woman's risk of breast cancer." More research And they said this was the first time a commonly eaten food had been linked to an increased risk of breast cancer in older women. However, they warned that more research was needed to confirm the findings which may have been affected because they only took into account intake of the fruit, but not grapefruit juice. Breast cancer accounts for almost a third of all cancers in women, and previous lifestyle factors linked to the disease include drinking alcohol and being overweight. Dr Joanne Lunn, a nutrition scientist at the British Nutrition Foundation said: "This is an interesting study of a large group of post-menopausal women whose diet and health have been followed for many years. "However, this study is simply a piece of the jigsaw that will eventually help us to understand how our diets affect our health. "Although we are beginning to get a better awareness of how our diets can modify the risk of> diseases such as cancer, we are still a long way from identifying particular foods that might specifically increase or decrease risk." However, she said that some dietary patterns are associated with a reduced risk of certain cancers and that a diet rich in a variety of different fruits and vegetables could help reduce the risk of heart disease and some cancers. > > > > Peter H > > > > > Mail is the world's favourite email. Don't settle for less, sign up for your freeaccount today.> Peter H Mail is the world's favourite email. Don't settle for less, sign up for your free account today. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 18, 2007 Report Share Posted July 18, 2007 Hi Kym I'm no expert, but according to a leaflet from " Europeans for Medical Progress " , the cancer which occurs in mice is completely different in every way to that which occurs in humans... BB Peter - " Kym Amps " <kymontrip Wednesday, July 18, 2007 8:47 AM Re: Re: Grapefruit link to breast cancer > A quick word about cancer in non human animals - it is > very misleading. The most celebrated is that of > smoking. Lab animals didn't contract cancer even after > being subjected to 24/7 cigarette smoke, both active > and passive. I would go with the human studies. > > > --- Marcy <imgreen03 wrote: > > > Things are not always what they seem, are they? > > > > T. Colin Campbell (The China Study), who discovered > > dioxin, was working on a project to investigate the > > high prevalence of liver cancer in filipino > > children. It was thought the cause was aflatoxin, a > > mold found in peanuts and corn, one of the most > > potent carcinogens ever discovered. > > > > To combat childhood malnutrition, this project was > > also supposed to ensure children got as much protein > > as possible. It was widely thought at that time > > that childhood malnutrition was caused by lack of > > protein, especially the animal variety. > > > > Studies then revealed that: > > 1) children who ate the highest-protein diets were > > the ones most likely to get liver cancer, and > > 2) rats who were fed both aflatoxin and 20% of > > their diet as protein got liver cancer, while rats > > who were fed aflatoxin and 5% of their diet as > > protein did NOT get liver cancer. These results > > were 0% and 100%; 5% protein + carcinogen = NO > > cancer; 20% protein + carcinogen = everyone gets > > cancer. > > > > What does this have to do with grapefruits? Just > > what a few of you have been pointing out. Just as > > the aflatoxin wasn't the entire picture, neither are > > those grapefruits. > > > > And, by the way, I wonder how many people in the > > world die from eating grapefruit? Why don't they > > compare the risk of cancer from grapefruit with that > > of animal products? > > > > Maybe when combined with a high level of protein, > > you get cancer? > > > > We are right to ask questions when we see a study > > like this one. I always want to follow the money. > > For example, who funded this grapefruit study? > > > > Marcy > > > > > > > > - > > yarrow > > > > Tuesday, July 17, 2007 10:23 AM > > Re: Grapefruit link to > > breast cancer > > > > > > Exactly! At first I thought, what if all the > > grapefruit eaters are > > eating sausage and bacon for breakfast, and eat > > grapefruit to balance > > the fat? I have some neighbors who were doing this > > for a while. Or > > perhaps the grapefruits had some pesticide residue > > that caused this > > effect. > > > > But then I realized the study posited a chemical > > pathway implicating > > grapefruit and also played loose with statistics. > > I'm not sure what > > the researchers mean by " higher risk " : do they > > mean that more women > > developed BC? Or that they assume the risk of > > developing it is higher > > because grapefruit inhibits cytochrome P450 3A4 > > (CYP3A4) and thus > > allows higher estrogen levels? Maybe what they > > measured was estrogen > > levels, which are correlated with higher risk of > > bc. > > > > Re statistics: the " up to 30 percent higher " has > > no meaning unless > > you know what it's based on. So if the risk is 1 > > percent, then > > grapefruit would make it 1.3 percent. If it's 15 > > percent, it goes to > > 22 percent. But the way it's written and the way > > it's often > > interpreted in the lay press is that the risk goes > > from 1 to 31 > > percent, or from 15 to 45 percent. Huge > > difference. > > > > I eat grapefruit only in the winter, as a fruit, a > > whole one at a time. > > > > At 7:00 AM +0000 7/17/07, heartwerk wrote: > > >I would like to know what other constants they > > considered in their > > >research, before I believe this. Incidentally I > > don't eat > > >grapefruits at all, but doubt the conclusions > > they have come to. > > > > > >Jo > > > > > > , Peter VV > > <swpgh01 wrote: > > >> > > >> Grapefruit link to breast cancer > > >> > > >> Eating too much grapefruit could increase risks > > of > > >breast cancer > > >> > > >> Eating grapefruit every day could raise the > > risk of developing > > >breast cancer by almost a third, US scientists > > say. A study of > > >50,000 post-menopausal women found eating just a > > quarter of a > > >grapefruit daily raised the risk by up to 30%. > > The fruit is thought > > >to boost levels of oestrogen - the hormone > > associated with a higher > > >risk of the disease, the British Journal of > > Cancer reported. But > > >the researchers and other experts said more > > research was still > > >needed. This is an interesting study, but is > > simply > > >a piece of the jigsaw that will eventually help > > us to understand how > > >our diets affect our health > > >> > > >> > > >> Dr Joanne Lunn > > >> > > >> The women had to fill in questionnaires saying > > how often they ate > > >grapefruit and how big their portions were. > > Oestrogen important > > >The researchers, at the universities of South > > California and Hawaii, > > >found that women who ate one quarter of a > > grapefruit or more every > > >day had a higher risk of breast cancer than those > > who did not eat the > > >fruit at all. Previous studies have shown that a > > molecule called > > >cytochrome P450 3A4 (CYP3A4) is involved in > > metabolising oestrogen > > >hormones. And grapefruit may boost blood > > oestrogen levels by > > >inhibiting this molecule, allowing the hormones > > to build up. The > > >researchers found that in women who ate at least > > a quarter of a > > >grapefruit daily, levels of oestrogen were > > higher. They said: " It > > >is well established that oestrogen is associated > > with breast cancer > > >risk. " Therefore, if grapefruit intake affects > > oestrogen metabolism > > >leading to higher circulating levels, then it is > > biologically > > >plausible that regular intake of grapefruit would > > >> increase a woman's risk of breast cancer. " More > > research And > > >they said this was the first time a commonly > > eaten food had been > > >linked to an increased risk of breast cancer in > > older women. > > >However, they warned that more research was > > needed to confirm the > > >findings which may have been affected because > > they only took into > > >account intake of the fruit, but not grapefruit > > juice. Breast > > >cancer accounts for almost a third of all cancers > > in women, and > > >previous lifestyle factors linked to the disease > > include drinking > > >alcohol and being overweight. Dr Joanne Lunn, a > > nutrition scientist > > >at the British Nutrition Foundation said: " This > > is an interesting > > >study of a large group of post-menopausal women > > whose diet and health > > >have been followed for many years. " However, this > > study is simply a > > >piece of the jigsaw that will eventually help us > > to understand how > > >our diets affect our health. " Although we are > > beginning to get a > > >better awareness of how our diets can modify the > > risk of > > >> diseases such as cancer, we are still a long > > way from identifying > > >particular foods that might specifically increase > > or decrease > > > === message truncated === > > > > > __________________________ ________ > Get your own web address. > Have a HUGE year through Small Business. > http://smallbusiness./domains/?p=BESTDEAL > > > To send an email to - > Quote Link to comment Share on other sites More sharing options...
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