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Leyden cells

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Leydig's cell - a cell in the testes that secretes the hormone

testosterone. Or the less familiar scientific understandings -

 

An Overview of the Repertoire in Testis

 

The occurrence of these molecules is highly dependent on the

species, the developmental age of the testis and its endocrine

environment. Although the MMP-18, MMPs 23-26 and MMP-28 are present

in the testis,50,62-65 there is no indication relative to their

cellular localisation.

 

In fact, most of the information available are on the gelatinases

MMP-2 and MMP-9 probably because of the avaibility of a rapid and

simple biological test i.e., the gelatin zymography. The human fetal

testis is also the site of expression of MMPs and TIMPs.

 

66 In the mouse, MMPs 2 and 9 are detected in fetal testes together

with the TIMPs 1-3 and EMMPRIN.13 FSH regulation has been explored

using 20-day old rat Sertoli cells, and it was shown that FSH

regulated MMP-2 but not MMP-9 or MMP-14, and TIMP-1 and TIMP-

2.17,51,53-55,57-60,67,68 Cytokines largely involved in testicular

physiology such as TNFá (tumor necrosis factor á), TGFâ3

(transforming growth factor â3) and FGF2 (basic fibroblast growth

factor) have also been shown to regulate various MMPs and TIMPs in a

culture or coculture model of testicular cells.53-55,58,61.

 

Leydig cells have been shown to express ADAM31,69 as well as TIMP-2

throughout development.70,71 It is yet unknown whether these

proteins are under gonadotropin regulation in Leydig cells.

 

lol - chrism

 

, " Shiva "

<shiva wrote:

>

> hi

> what r Leyden cells ? wher r they located in our body.

> r they imp for kundalini awakening

> -shiva

>

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Leydin, a novel human serine protease expressed by the Leydig cells of

the testis.

 

, " Shiva "

<shiva wrote:

>

> hi

> what r Leyden cells ? wher r they located in our body.

> r they imp for kundalini awakening

> -shiva

>

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